Abstract: Disclosed herein are devices and methods for creating a shunt between two vessels or lumens within a patient. While these devices and methods are generally described with regard to treatment of hypertension (e.g., pulmonary arterial hypertension) and/or right heart failure/disfunction, they can be used with a variety of different vessels and lumens for other purposes. The devices include puncturing guidewire embodiments that can more accurately pierce two vessels, as well as snare catheter designs that can prevent unwanted damage from a puncturing guidewire.

Abstract: Methods and devices for increasing oxygenation levels in the blood supply and thereby treating the condition of hypoxemia. Multiple approaches such as pressure reduction in the pulmonary circulatory system, reducing triggering mechanisms in the main pulmonary artery and restricting flow in the pulmonary circulatory system are disclosed. Interventions associated with those approaches can including shunting, restrictors, compliance devices, pharmacologic substances, etc.

Abstract: Methods and devices for increasing oxygenation levels in the blood supply and thereby treating the condition of hypoxemia. Multiple approaches such as pressure reduction in the pulmonary circulatory system, reducing triggering mechanisms in the main pulmonary artery and restricting flow in the pulmonary circulatory system are disclosed. Interventions associated with those approaches can including shunting, restrictors, compliance devices, pharmacologic substances, etc.

Abstract: Methods and techniques are disclosed for performing transcatheter procedures on a patient that result in similar blood flow changes to the surgical Blalock-Taussig procedure, the Glenn procedure, and the Fontan procedure. Since these transcatheter procedures do not necessarily involve open chest surgery, they tend to be less traumatic for the patient, quicker and easier to perform, and may result in better patient outcomes.

Abstract: Methods and devices for increasing oxygenation levels in the blood supply and thereby treating the condition of hypoxemia. Multiple approaches such as pressure reduction in the pulmonary circulatory system, reducing triggering mechanisms in the main pulmonary artery and restricting flow in the pulmonary circulatory system are disclosed. Interventions associated with those approaches can including shunting, restrictors, compliance devices, pharmacologic substances, etc.

Abstract: Devices and methods of treating conditions cause or exacerbated by excessive fluid pressures or retentions, such as pulmonary hypertension, that involves shunting excessive fluid pressure from one bodily chamber or vessel to another bodily chamber or vessel.

Abstract: Devices and methods of treating fluid retention caused by congestive heart failure or other conditions resulting in edema, lymphoedema, or significant fluid retention (e.g., deep vein thrombosis, cellulitis, venous stasis insufficiency, or damage to the lymphatic network) are described. Specifically, a treatment device is used to create a passage or cannula between the lymphatic system (or other area of the body) and an external drainage device. This device can be only temporarily located in the patient or can be implanted within the patient for longer periods of time. The physician can safely and reliably remove excess fluid from the body via the device and optionally inject other treatment agents.

Abstract: This disclosure provides marking implements for making radiopaque markings, and methods of using the same.

Abstract: This disclosure provides marking implements for making radiopaque markings, and methods of using the same.