Abstract: A method of controlling cooling fluid flow through a radiator system having multiple radiator cores comprises flowing cooling fluid through the radiator system, the radiator system comprising a first radiator core and a second radiator core, sensing a first temperature of ambient air, comparing the first temperature to a first threshold temperature and reducing flow through the first radiator core if the first temperature is below the first threshold temperature. The first radiator core has a first valve, and the second radiator core can have a second valve. The first valve can be opened to allow for parallel flow of cooling fluid through the first radiator core and the second radiator core between an inlet manifold and an outlet manifold and closed to interrupt flow of cooing fluid through the first radiator core between the inlet manifold and the outlet manifold.

Abstract: The presently disclosed systems and methods provide monitoring systems and methods for assessing risk based on individual risk control categories. In an embodiment, the risk is assessed based on data for a particular control category. A subset of the data is weighted according to a first weighting function, and a different subset of the data is weighted according to a second weighting function. The weighted data is combined to generate a control health index that may be used to assess risk.

Abstract: Provided herein are methods, systems, and devices for occluding the LAA of a patient's heart. The methods, systems, and devices can be used to percutaneously occlude the LAA, decreasing the risk of thromboembolic events associated with AF.

Abstract: The present disclosure relates to heterobifunctional molecules, referred to as cytotoxicity targeting chimeras (CyTaCs) or antibody recruiting molecules (ARMs) that are able to simultaneously bind a target cell-surface protein as well as an exogenous antibody protein. The present disclosure also relates to agents capable of binding to a receptor on a surface of a pathogenic cell and inducing the depletion of the pathogenic cell in a subject for use in the treatment of cancer, inflammatory diseases, autoimmune diseases, viral infection, or bacterial infection.

Abstract: An object processing system is disclosed that includes a mobile system for moving from a proximal base toward a plurality of objects to be processed, and a programmable motion device supported on the mobile unit at a proximal end of the programmable motion device, the programmable motion device including an end-effector at a distal end thereof, the end-effector including a first stationary portion that remains stationary with respect to the distal end of the programmable motion device, and a second movable portion that moves with respect to the first stationary portion, the second movable portion for contacting at least one object of the plurality of objects for urging the at least one object from the plurality of objects toward the mobile system.

Abstract: An object processing system is disclosed that includes a mobile unit for moving from a proximal location toward a plurality of objects in a trailer of a tractor trailer, the mobile unit including at least one conveyor section for transporting any objects on the at least one conveyor section out of the trailer, the at least one conveyor section including a leading edge at a front of the mobile unit as the mobile unit moves toward the plurality of objects in the trailer, and a kicker roller adjacent the leading edge of the at least one conveyor section, the kicker roller being positioned in front of the at least one conveyor section for urging the plurality of objects onto the at least one conveyor section.

Abstract: The efficient storage of transformation information in a switch is provided. A respective port of the switch can include a memory device capable of storing transformation information. During operation, the switch can apply a selection mechanism to the transformation information learned at the switch for identifying a target port. The switch can then store the information in the memory device of the target port. Upon receiving a packet, the ingress port can apply the selection mechanism to the header information of the packet for determining a location of a first piece of transformation information associated with the packet. The ingress port can obtain the first piece of transformation information by looking up the header information in the location and storing it in a local memory device. The ingress port can then transform the packet based on the first piece of transformation information for determining an egress port for the packet.

Abstract: Systems and methods for electronic pressure control of pumps in a dual pump system. The system may include a controller, a primary pump operated by the controller to maintain a system pressure in a flow path at a first pressure setpoint; a pressure transducer reading the system pressure and providing the system pressure to the controller; and a secondary pump operated by the controller to maintain the system pressure at a second pressure setpoint, the second pressure setpoint being less that the first pressure setpoint.

Abstract: Various embodiments are directed to processing conversions of digital assets to other digital assets. An example method includes determining a source exchange rate for a source digital asset and a fiat currency, determining a target exchange rate for a target digital asset and a fiat currency, and generating an aggregated conversion rate for the source digital asset and the target digital asset using the source exchange rate and the target exchange rate. The method further includes executing a digital asset conversion, which includes causing source digital asset units to be debited from a source digital asset user account and causing target digital asset units to be credited to a target digital asset user account, and subsequently executing fiat currency transactions (e.g., settlements) with a first digital asset exchange system associated with the source digital asset and a second digital asset exchange system associated with the target digital asset.

Abstract: Systems and methods for manual gesture recognition to control prosthetic devices. Low encumbrance systems utilizing glove-based recognition to control prosthetic devices. Prosthetic control systems and methods are also provided utilizing elements for application on the user's fingernails.

Abstract: A method for maintaining a tube heat exchanger includes: obtaining measurement signals resulting from the passage of a measurement probe in the tubes of the heat exchanger, determining a reference time series corresponding to an average, at each instant, of the measurement signals, synchronising each measurement signal with the reference time series by applying a dynamic time warping, DTW, to said measurement signal and the reference time series, and searching for a potential anomaly by measuring a potential local deviation of a measurement signal with respect to the other measurement signals.

Abstract: Provided is a semi-active seat suspension system that minimizes vibration and energy transmission from a vibration/energy source, such as a motor vehicle, to a seated occupant by means of a spring and computer-controlled damper suspension system. Using a variety of sensors to determine an ideal damping rate at a given point in time, the system adjusts the damping rate in real time to provide the best possible ride to the occupant given the constraints of the system.

Abstract: The disclosure includes a doorbell having a visitor detection system that can comprise at least one of a camera, a microphone, and a motion detector. The method for using the doorbell can comprise recording, via the camera, video data that represents a video. The method can also comprise recording, via the microphone, audio data that represents audio. The method of using the doorbell can comprise transmitting at least a portion of the video data and at least a portion of the audio data, to a remote computing device that is communicatively coupled to the doorbell. The method can also comprise transmitting the video data and the audio data to a remote server that is communicatively coupled to the doorbell.

Abstract: The present disclosure relates to methods of inducing a pan-sarbecoronavirus variant immune response for the treatment and prevention of coronavirus infections.

Abstract: The present disclosure is based in part on probes, compositions, methods, and kits for simultaneous, multiplexed spatial detection and quantification of protein and/or nucleic acid expression in a user-defined region of a tissue, user-defined cell, and/or user-defined subcellular structure within a cell.

Abstract: An adapted die carrier assembly for a gripping device includes a conventional die carrier, a die adapter, and an alternate die that is not configured to directly engage die receptacles of the conventional die carrier. The die adapter is secured to the conventional die carrier, and the alternate die is secured to the die adapter. The die adapter includes a receiving slot and one or more lobes. Each lobe is slidingly secured within one of the die receptacles of the conventional die carrier. Each lobe has an outer surface that is reciprocal to the die receptacles. The alternate die is slidingly secured within the receiving slot of the die adapter. The alternate die includes a gripping surface.

Abstract: The present disclosure relates to a nucleic acid molecule comprising 5?-UTR and/or 3?-UTR sequences that yield high translation levels. Aspects of the disclosure further relate to nucleic acid molecules suitable for use as a vaccine in the treatment and prevention of infectious diseases, including those caused by a coronavirus, compositions comprising said nucleic acid molecules and methods of treating or preventing infectious diseases.

Abstract: The present invention provides novel antigen binding peptides, such as an antibody or antibody fragment, that specifically bind to selective FXIa inhibitors and/or dual inhibitors of FXIa, and plasma kallikrein. The present invention further relates to methods of reducing the antithrombotic effect of FXIa inhibitors by administering to a subject a pharmaceutically effective dose of the antigen binding peptides provided herein. In addition, the present invention provides detection reagents and methods for detecting the level of the inhibitors of FXIa in a biological sample.