Patents by Inventor Joseph R. Williamson

Joseph R. Williamson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5837738
    Abstract: A method is disclosed for inhibiting nitric oxide formation in a warm blooded mammal afflicted with an acute or chronic inflammatory disease which comprises administering to said mammal an effective nitric oxide inhibitory amount of methyl-, or 1,1-dimethyl-, or amino-substituted guanidines.
    Type: Grant
    Filed: February 5, 1997
    Date of Patent: November 17, 1998
    Assignee: Washington University
    Inventors: Joseph R. Williamson, John A. Corbett, Michael L. McDaniel, Ronald G. Tilton
  • Patent number: 5710181
    Abstract: A method is disclosed for inhibiting nitric oxide formation in a warm blooded mammal afflicted with inflammatory bowel disease which comprises administering to said mammal an effective nitric oxide inhibitory amount of aminoguanidine.
    Type: Grant
    Filed: March 25, 1996
    Date of Patent: January 20, 1998
    Assignee: Washington University
    Inventors: Joseph R. Williamson, John A. Corbett, Michael L. McDaniel, Ronald G. Tilton
  • Patent number: 5358969
    Abstract: A method is disclosed for inhibiting nitric oxide formation in a warm blooded mammal afflicted with an acute or chronic inflammatory disease which comprises administering to said mammal an effective nitric oxide inhibitory amount of methyl-, or 1,1-dimethyl-, or amino-substituted guanidines.
    Type: Grant
    Filed: August 24, 1993
    Date of Patent: October 25, 1994
    Assignee: Washington University
    Inventors: Joseph R. Williamson, John A. Corbett, Michael L. McDaniel, Ronald G. Tilton
  • Patent number: 5246970
    Abstract: A method is disclosed for inhibiting nitric oxide formation in a warm blooded mammal which comprises administering to said mammal an effective nitric oxide inhibitory amount of aminoguanidine.
    Type: Grant
    Filed: June 30, 1992
    Date of Patent: September 21, 1993
    Assignee: Washington University
    Inventors: Joseph R. Williamson, John A. Corbett, Michael L. McDaniel, Ronald G. Tilton
  • Patent number: 5246971
    Abstract: A method is disclosed for inhibiting nitric oxide formation in a warm blooded mammal which comprises administering to said mammal an effective nitric oxide inhibitory amount of methylguanidine or dimethylguanidine.
    Type: Grant
    Filed: February 28, 1992
    Date of Patent: September 21, 1993
    Assignee: Washington University
    Inventors: Joseph R. Williamson, John A. Corbett, Michael L. McDaniel, Ronald G. Tilton
  • Patent number: 5047427
    Abstract: The invention provides a method to ameliorate or prevent the secondary damaging effects of diabetes by affecting oxidation of sorbitol in insulin-independent cells. Pyruvate salts and/or NAD.sup.+ precursors administered in a repetitive protocol provide protection against these secondary effects.
    Type: Grant
    Filed: October 31, 1988
    Date of Patent: September 10, 1991
    Assignee: Washington University
    Inventor: Joseph R. Williamson
  • Patent number: 4358003
    Abstract: A floating-caliper disc brake (10) includes a non-rotating torque member (36). A caliper (22) straddles the brake disc (12) and is carried in fixed radial and circumferential position by the torque member (36). Axial movement of the caliper (22) relative to the brake disc (22) is provided for by roller members (58) between the caliper (22) and the torque member (36). The torque member (36) and the caliper (22) both have axially-extending grooves (52, 54) which in registry cooperate to define axially-extending apertures (56) between the caliper and the torque member. The roller members (58) are received in the axially-extending apertures (56) between the caliper (22) and the torque member (36). The roller members (58) are the sole torque-transmitting structure between the caliper (22) and the torque member (36). Rolling of the caliper (22) on the roller members (58) provides for axial movement of the caliper (22) relative to the brake disc (12) and the torque member (36).
    Type: Grant
    Filed: July 30, 1980
    Date of Patent: November 9, 1982
    Assignee: The Bendis Corporation
    Inventors: Donald D. Johannesen, Joseph R. Williamson
  • Patent number: 3965969
    Abstract: A convertible food service cart including a cold tray compartment and a conversion compartment, both of which are insulated and cooled by respective refrigeration systems. The conversion compartment is provided with a plurality of electrical plugs which connect in parallel and which are vertically spaced within the conversion compartment to receive electrical plug receptacles affixed to the hot food conversion trays. The conversion trays include a conductive, flat, heating element which is sandwiched between two sheets of thin, insulating material and provides uniform temperature throughout. The warm food is originally placed in the conversion compartment in refrigerated condition. An automatic programmer is provided to terminate the refrigeration action in the conversion compartment and to activate the tray heating plugs in predetermined time to properly heat the warm food immediately prior to serving.
    Type: Grant
    Filed: June 11, 1973
    Date of Patent: June 29, 1976
    Inventor: Joseph R. Williamson