Abstract: A medical product includes a bladder, a filtration device, and a sterile product concentrate. The bladder has a perimeter seal and defining a sterile chamber. The filtration device includes a stem and a filter membrane disposed in line with the stem. The stem extends through the perimeter seal and has an inlet end accessible from outside of the perimeter seal and an outlet end in fluid communication with the sterile chamber. The filter membrane can have a nominal pore size in a range of approximately 0.1 ?m to approximately 0.5 ?m, wherein the filter membrane is shaped as a hollow fiber with a wall and pores residing in the wall of the fiber. The sterile product concentrate is disposed in the sterile chamber and adapted to be reconstituted by the introduction of a pharmaceutical fluid into the chamber through the filtration device.

Abstract: A frame for engaging at least two fluid containers includes: a first engagement member configured to secure at least a portion of one of the at least two fluid containers; a second engagement member configured to secure at least a portion of another one of the at least two fluid containers; and a body structure connected to the first engagement member and the second engagement member. The body structure is sized and shaped to index the at least two fluid containers with a powered injector system such that the at least two fluid injectors are held in an orientation and distance relative to each other for insertion into at least two pressure jackets associated with the powered injector system.

Abstract: A medical product includes a bladder, a filtration device, and a sterile product concentrate. The bladder has a perimeter seal and defining a sterile chamber. The filtration device includes a stem and a filter membrane disposed in line with the stem. The stem extends through the perimeter seal and has an inlet end accessible from outside of the perimeter seal and an outlet end in fluid communication with the sterile chamber. The filter membrane can have a nominal pore size in a range of approximately 0.1 ?m to approximately 0.5 ?m, wherein the filter membrane is shaped as a hollow fiber with a wall and pores residing in the wall of the fiber. The sterile product concentrate is disposed in the sterile chamber and adapted to be reconstituted by the introduction of a pharmaceutical fluid into the chamber through the filtration device.

Abstract: An improved apparatus, method and system are provided for medical liquid administration, including in particular liquid medication and/or flush solution infusions. The inventive apparatus includes a barrel, a plunger slidably disposed within the barrel and extending from a distal end thereof, and at least one medical liquid delivery line having a proximal end fixedly positioned relative to the barrel, wherein the medical delivery line is fluidly interconnectable proximal to the plunger and extends along at least a portion of the barrel and in a direction distally away from the distal end thereof. To accommodate the administration of both a liquid medication and flush solution, two coincidentally-positioned medical liquid delivery lines may be included, each of which may extend through the plunger to the valve. The valve may be positionable to accommodate the selective administration of a desired medical liquid through an interconnected catheter interconnection line.

Abstract: A medical liquid filling system and associated methods are provided, the system comprising a disposable and a drive system. The disposable includes a tubular member and a piston slidably disposed within the tubular member for retraction and advancement within at least a first portion of the tubular member. The disposable may include a seal member for sealing the first portion of the tubular member and may be interconnected to the piston for co-movement therewith. The drive system may include a piston drive member selectively interconnectable to the piston for driven advancement and retraction of the piston within the tubular member. The drive system may be interconnected to a controller, which may be operable to automate or semi-automate various filling operations. A user interface may be interconnected to the controller for providing input of various system operation parameters, which may be communicated to the controller to facilitate automated or semi-automated operation of the filling system.

Abstract: An improved apparatus, method and system are provided for medical liquid administration, including in particular liquid medication and/or flush solution infusions. The inventive apparatus includes a barrel, a plunger slidably disposed within the barrel and extending from a distal end thereof, and at least one medical liquid delivery line having a proximal end fixedly positioned relative to the barrel, wherein the medical delivery line is fluidly interconnectable proximal to the plunger and extends along at least a portion of the barrel and in a direction distally away from the distal end thereof. To accommodate the administration of both a liquid medication and flush solution, two coincidentally-positioned medical liquid delivery lines may be included, each of which may extend through the plunger to the valve. The valve may be positionable to accommodate the selective administration of a desired medical liquid through an interconnected catheter interconnection line.

Abstract: The present invention provides an inventive apparatus and method for docking of a male luer connector fluidly interconnected or interconnectable to a medical liquid source during one or repeated periods. As such, the invention has particular application to multiple-dose medication therapy procedures. The docking apparatus comprises a holding receptacle having a single access opening and a depressible member disposed in the holding receptacle. The holding receptacle is adapted for retentive engagement with a male luer connector (e.g. via complementary threading), wherein upon docking a nozzle of the male luer connector is isolated within the holding receptacle. An anti-bacterial material may be readily applied to a top surface of the depressible member prior to docking so that the forward edge of the nozzle of the male luer connector contacts the anti-bacterial material when docked. The docking apparatus may be provided with lateral and rearward handling members to facilitate docking procedures.

Abstract: An improved sterile docking apparatus for a medical-liquid, male connectors includes a holding member having an opening for matably receiving a nozzle end of a medical-liquid, male connector therethrough, and a deformable member disposed across the opening, wherein the deformable member is deformable to envelop and thereby isolate a nozzle end of a medical-liquid, male connector that is inserted into the opening of the holding member. The deformable member may be resilient, wherein it substantially returns to an initial configuration after removal of a nozzle end of a medical-liquid, male connector from the opening of the holding member. An interconnection surface may be provided on the holding member of the docking apparatus to interface with a complimentary interconnection surface of a medical-liquid, male connector so as to maintain the nozzle end of the medical-liquid, male connector in an enveloped position during docking.

Abstract: An improved sterile docking apparatus for a medical-liquid, male connectors includes a holding member having an opening for matably receiving a nozzle end of a medical-liquid, male connector therethrough, and a film member disposed across the opening, wherein the film member is stretchable to envelope and thereby isolate a nozzle end of a medical-liquid, male connector that is inserted into the opening of the holding member. The film member may be elastic, wherein it substantially returns to an initial configuration after removal of a nozzle end of a medical-liquid, male connector from the opening of the holding member. An interconnection surface may be provided on the holding member of the docking apparatus to interface with a complimentary interconnection surface of a medical-liquid, male connector so as to maintain the nozzle end of the medical-liquid, male connector in an enveloped position during docking.

Abstract: An inventive method, system and apparatus are provided for syringe handling, and more particularly, for syringe labeling, filling and capping operations. To facilitate syringe handling, an inventive apparatus includes a plurality of syringe bodies interconnected in a predetermined orientation by a belt. Such belt may be of pliable construction and may define a predetermined spacing in between adjacent ones of the syringe bodies. The syringe handling apparatus may provide for the placement of contents-related information on belt segments between adjacent syringe bodies and for separating the belt segments, wherein a flap is left interconnected to each syringe body. The syringe handling apparatus may provide for automated filling of the syringe bodies wherein cap removal, filling and cap replacement operations are completed free from manual handling. An improved cap and method for capping medical male luer fittings is also provided.