Abstract: A sterilizable pouch comprising first and second opposing webs sealed together along two peripheral side edges. An unsealed edge of the first web extending beyond the opposing lip edge of the second web to form a flap. One of the webs having sealing means disposed adjacent to and spaced from the lip edge of the second web. The sealing means having sufficient width to permit sealing of both (a) the space on the web with the sealing means defined by the border of the sealing means and the lip edge of the second web and (b) an area on the web without sealing means adjacent the lip edge sufficient to form a contaminant-proof seal when the flap is closed and sealed.

Abstract: A rotary plug valve having a plug member rotatable in a valve housing member between an open position and a closed position, the plug member carrying a sealing ring, such as an O-ring seal or the like, in a groove provided on its surface between its port openings, the O-ring seal being adapted to encircle one of the ports of the housing member when the plug member is in the closed position. The rotary plug valve is capable of two-way flow therethrough, and this is realized by providing means for equalizing the pressure across the unsupported portion or segment of the O-ring seal when the same is passing across one of the ports of the valve housing. By such an arrangement, the pressure across the O-ring seal may be equalized in certain situations such as when the plug member is rotated towards and approaches a position for closing the valve and when the plug member is rotated towards and approaches the full open position and this prevents clipping or shearing of the O-ring seal.