Patents by Inventor Joseph T. Delaney, Jr.
Joseph T. Delaney, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240139097Abstract: The present disclosure relates to injectable compositions sterile injectable fluid compositions comprising a polysaccharide having a color in the visible spectrum, methods of forming the same, kits containing the same, and methods for performing agent-assisted procedures in a patient using the same.Type: ApplicationFiled: January 5, 2024Publication date: May 2, 2024Applicant: Boston Scientific Scimed, Inc.Inventors: Joseph T. Delaney, JR., Samuel Raybin, John Kummailil, Matthew B. Hollyer
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Publication number: 20240117121Abstract: In some aspects, the present disclosure pertains to multi-arm polymers that comprise a core and a plurality of polymer segments having a first end that is covalently attached to the core and (a) a second end comprising a moiety that comprises a reactive end group, wherein the polymer segments comprise one or more hydrophilic aprotic NMP-polymerizable monomers, and wherein the reactive multi-arm polymer comprises nitroxide radicals or (b) a second end comprising a moiety that comprises an alkoxyamine group, wherein the core is a polyol residue, and wherein the polymer segments comprise one or more NMP-polymerizable monomers. In some aspects, the present disclosure pertains to a multifunctional alkoxyamine molecule comprising a core and a plurality of alkoxyamine groups covalently attached to the core, wherein the core is a polyol residue.Type: ApplicationFiled: October 18, 2023Publication date: April 11, 2024Applicant: Boston Scientific Scimed, Inc.Inventors: Joseph T. Delaney, JR., Paul V. Grosso, John Kummailil, Tatyana Dyndikova, Carey Rehder
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Patent number: 11938216Abstract: The present disclosure relates to injectable compositions sterile injectable fluid compositions comprising a polysaccharide having a color in the visible spectrum, methods of forming the same, kits containing the same, and methods for performing agent-assisted procedures in a patient using the same.Type: GrantFiled: July 20, 2017Date of Patent: March 26, 2024Assignee: Boston Scientific Scimed, Inc.Inventors: Joseph T. Delaney, Jr., Samuel Raybin, John Kummailil, Matthew B. Hollyer
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Publication number: 20240026081Abstract: In some aspects, the present disclosure pertains to a multi-arm polymer comprising a core and a plurality of polyoxazoline segments (or arms) having a first end that is covalently attached to the core and a second end comprising a moiety that comprises a reactive group. In some aspects, systems are provided that comprise a first composition comprising such a multi-arm polymer and a second composition comprising a multifunctional compound that comprises functional groups that are reactive with the reactive groups of the multi-arm polymer. In some aspects, systems are provided that comprise crosslinked reaction products of such a multi-arm polymer and such a multifunctional compound.Type: ApplicationFiled: September 27, 2023Publication date: January 25, 2024Applicant: Boston Scientific Scimed Inc.Inventors: Joseph T. Delaney, JR., Paul V. Grosso, John Kummailil, Tatyana Dyndikova, Carey Rehder
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Patent number: 11851522Abstract: A polymeric material includes a polyisobutylene-polyurethane block copolymer. The polyisobutylene-polyurethane block copolymer includes soft segments, hard segments, and end groups. The soft segments include a polyisobutylene diol residue. The hard segments include a diisocyanate residue. The end groups are bonded by urea bonds to a portion of the diisocyanate residue. The end groups include a residue of a mono-functional amine.Type: GrantFiled: September 23, 2022Date of Patent: December 26, 2023Assignee: CARDIAC PACEMAKERS, INC.Inventors: Joseph T. Delaney, Jr., Andrew J. Ro, David R. Wulfman, Niraj Gurung, Patrick Willoughby
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Patent number: 11820868Abstract: In some aspects, the present disclosure pertains to multi-arm polymers that comprise a core and a plurality of polymer segments having a first end that is covalently attached to the core and (a) a second end comprising a moiety that comprises a reactive end group, wherein the polymer segments comprise one or more hydrophilic aprotic NMP-polymerizable monomers, and wherein the reactive multi-arm polymer comprises nitroxide radicals or (b) a second end comprising a moiety that comprises an alkoxyamine group, wherein the core is a polyol residue, and wherein the polymer segments comprise one or more NMP-polymerizable monomers. In some aspects, the present disclosure pertains to a multifunctional alkoxyamine molecule comprising a core and a plurality of alkoxyamine groups covalently attached to the core, wherein the core is a polyol residue.Type: GrantFiled: August 21, 2020Date of Patent: November 21, 2023Assignee: Boston Scientific Scimed, Inc.Inventors: Joseph T. Delaney, Jr., Paul V. Grosso, John Kummailil, Tatyana Dyndikova, Carey Rehder
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Patent number: 11807720Abstract: In some aspects, the present disclosure pertains to a multi-arm polymer comprising a core and a plurality of polyoxazoline segments (or arms) having a first end that is covalently attached to the core and a second end comprising a moiety that comprises a reactive group. In some aspects, systems are provided that comprise a first composition comprising such a multi-arm polymer and a second composition comprising a multifunctional compound that comprises functional groups that are reactive with the reactive groups of the multi-arm polymer. In some aspects, systems are provided that comprise crosslinked reaction products of such a multi-arm polymer and such a multifunctional compound.Type: GrantFiled: August 21, 2020Date of Patent: November 7, 2023Assignee: Boston Scientific Scimed, Inc.Inventors: Joseph T. Delaney, Jr., Paul V. Grosso, John Kummailil, Tatyana Dyndikova, Carey Rehder
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Patent number: 11660379Abstract: An implantable medical device includes a polymer substrate and at least one nanofiber. The polymer substrate includes a surface portion extending into the polymer substrate from a surface of the substrate. The at least one nanofiber includes a first portion and a second portion. The first portion is interpenetrated with the surface portion of the substrate, and mechanically fixed to the substrate. The second portion projects from the surface of the substrate.Type: GrantFiled: March 22, 2022Date of Patent: May 30, 2023Assignee: Cardiac Pacemakers, Inc.Inventors: David R. Wulfman, Danielle Frankson, Adeniyi O. Aremu, Angelo Fruci, Gregory J. Sherwood, Mary M. Byron, Joseph T. Delaney, Jr., Adam McGraw
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Publication number: 20230149974Abstract: Methods of treating a substrate, e.g., forming a coating on the substrate, are described. The method may include applying a solution comprising a multifunctional molecule or a multifunctional-polymer molecule to at least a portion of a surface of the substrate. The surface may comprise a metal or metal alloy and the multifunctional molecule or a multifunctional-polymer molecule may bond to the surface via at least one sulfur group of a plurality of sulfur groups of the multifunctional molecule. The method may include combining the multifunctional molecule with a polymer molecule to form the multifunctional polymer molecule before or after applying the solution. The polymer molecule may bond to an internal carbon group or a terminal sulfur group of the multifunctional molecule.Type: ApplicationFiled: November 10, 2022Publication date: May 18, 2023Applicant: Boston Scientific Scimed, Inc.Inventors: Joseph T. DELANEY, JR., John KUMMAILIL, Paul V. GROSSO, Yen-Hao HSU
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Publication number: 20230127824Abstract: In some embodiments, the present disclosure pertains to systems for forming a hydrogel that comprise (a) a first composition that comprises a polyiodinated polyamino compound and (b) a second composition that comprises a reactive multi-arm polymer that comprises a plurality of hydrophilic polymer arms having reactive end groups that are reactive with the amino groups of the polyiodinated polyamino compound. In some embodiments, the present disclosure pertains to medical hydrogels that are formed by reacting a polyiodinated polyamino compound and a reactive multi-arm polymer that comprises a plurality of hydrophilic polymer arms having reactive end groups that are reactive with the amino groups of the polyiodinated polyamino compound. In some embodiments, the present disclosure pertains to methods of making polyiodinated polyamino compounds.Type: ApplicationFiled: October 24, 2022Publication date: April 27, 2023Applicant: Boston Scientific Scimed Inc.Inventors: Joseph T. Delaney, JR., Kolbein Kolste, Tatyana Dyndikova, Yen-Hao Hsu
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Patent number: 11491338Abstract: A method of making a feed-thru connector assembly includes inserting a conductor within an opening within a housing of a pulse generator and dispensing a sealant in a gap between the conductor and portions of the housing adjacent to the conductor that define the opening of the housing and curing the sealant to form a seal comprising a polyisobutylene cross-linked network.Type: GrantFiled: November 30, 2018Date of Patent: November 8, 2022Assignee: Cardiac Pacemakers, Inc.Inventors: Michael J. Kane, Joseph T. Delaney, Jr., Kasyap Seethamraju
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Patent number: 11472911Abstract: A polymeric material includes a polyisobutylene-polyurethane block copolymer. The polyisobutylene-polyurethane block copolymer includes soft segments, hard segments, and end groups. The soft segments include a polyisobutylene diol residue. The hard segments include a diisocyanate residue. The end groups are bonded by urea bonds to a portion of the diisocyanate residue. The end groups include a residue of a mono-functional amine.Type: GrantFiled: January 15, 2019Date of Patent: October 18, 2022Assignee: Cardiac Pacemakers, Inc.Inventors: Joseph T. Delaney, Jr., Andrew J. Ro, David R. Wulfman, Niraj Gurung, Patrick Willoughby
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Publication number: 20220211919Abstract: An implantable medical device includes a polymer substrate and at least one nanofiber. The polymer substrate includes a surface portion extending into the polymer substrate from a surface of the substrate. The at least one nanofiber includes a first portion and a second portion. The first portion is interpenetrated with the surface portion of the substrate, and mechanically fixed to the substrate. The second portion projects from the surface of the substrate.Type: ApplicationFiled: March 22, 2022Publication date: July 7, 2022Inventors: David R. Wulfman, Danielle Frankson, Adeniyi O. Aremu, Angelo Fruci, Gregory J. Sherwood, Mary M. Byron, Joseph T. Delaney, JR., Adam McGraw
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Publication number: 20220204655Abstract: The present disclosure pertains to iodinated polysaccharide compounds that comprise a polysaccharide backbone that comprises a plurality of carboxyl groups and a plurality of iodinated side groups. The present disclosure also pertains iodinated polysaccharide compounds in which at least a portion of carboxyl groups that are present in a carboxyl-containing polysaccharide chain are functionalized with a plurality of iodinated side groups. Other aspects of the present disclosure pertain to methods of forming iodinated polysaccharide compounds, medical compositions comprising iodinated polysaccharide compounds, medical procedures comprising introducing such medical compositions into or between tissue of a patient, and medical kits that comprise such medical compositions.Type: ApplicationFiled: December 20, 2021Publication date: June 30, 2022Inventors: Joseph T. Delaney, JR., Kolbein Kolste, Tatyana Dyndikova
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Patent number: 11324860Abstract: An implantable medical device includes a polymer substrate and at least one nanofiber. The polymer substrate includes a surface portion extending into the polymer substrate from a surface of the substrate. The at least one nanofiber includes a first portion and a second portion. The first portion is interpenetrated with the surface portion of the substrate, and mechanically fixed to the substrate. The second portion projects from the surface of the substrate.Type: GrantFiled: August 9, 2017Date of Patent: May 10, 2022Assignee: Cardiac Pacemakers, Inc.Inventors: David R. Wulfman, Danielle Frankson, Adeniyi O. Aremu, Angelo Fruci, Gregory J. Sherwood, Mary M. Byron, Joseph T. Delaney, Jr., Adam McGraw
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Patent number: 11326022Abstract: In some aspects, the present disclosure pertains to multi-arm polymers that comprise a core, a plurality of polymer segments having a first end that is covalently attached to the core and a second end comprising a moiety that comprises a reactive group, wherein the polymer segments comprise one or more free-radical-polymerizable monomers. In some aspects, systems are provided that comprise a first composition comprising such a multi-arm polymer and a second composition comprising a multifunctional compound that comprises functional groups that are reactive with the reactive groups of the multi-arm polymer. In some aspects, systems are provided that comprise crosslinked reaction products of such a multi-arm polymer and such a multifunctional compound.Type: GrantFiled: August 21, 2020Date of Patent: May 10, 2022Assignee: BOSTON SCIENTIFIC SCIMED, INC.Inventors: Joseph T. Delaney, Jr., Carey Rehder, Tatyana Dyndikova, John Kummailil
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Patent number: 11185615Abstract: A method of making a solution including poly(ethylene terephthalate). The method includes dissolving poly(ethylene terephthalate) in a solvent mixture to form a solution, the solvent mixture including two solvent components. A Hansen Solubility Parameter Distance between the solvent mixture and HSP coordinates having a dispersion HSP of 18.02 MPa0.5, a polar HSP of 5.56 MPa0.5, and a hydrogen bonding HSP of 14.27 MPa0.5 is less than about 2 MPa0.5.Type: GrantFiled: October 10, 2019Date of Patent: November 30, 2021Assignee: Cardiac Pacemakers, Inc.Inventors: Joseph T. Delaney, Jr., David R. Wulfman, Adeniyi O. Aremu, Adegbola O. Adenusi
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Patent number: 11155933Abstract: A medical electrical lead includes an insulative lead body extending from a distal region to a proximal region and a conductor disposed within the insulative lead body and extending from the proximal region to the distal region. An electrode is disposed on the insulative lead body and is in electrical contact with the conductor. The medical electrical lead also includes a cross-linked hydrophilic polymer coating disposed over at least a portion of the electrode. The cross-linked hydrophilic polymer coating includes a fibrous matrix comprising a plurality of discrete fibers and pores formed between at least a portion of the fibers and a hydrophilic polyethylene glycol-containing hydrogel network disposed within the pores of the fibrous matrix.Type: GrantFiled: December 27, 2018Date of Patent: October 26, 2021Assignee: Cardiac Pacemakers, Inc.Inventors: Joseph T. Delaney, Jr., Jeannette C. Polkinghorne, Adegbola O. Adenusi, David R. Wulfman, Kasyap Seethamraju
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Publication number: 20210236690Abstract: Described herein are injectable in vivo crosslinking materials for use as soft tissue filler comprising (a) a reactive multi-arm polymer that comprises a plurality of hydrophilic polymeric arms, at least a portion of the hydrophilic polymeric arms comprising one or more reactive end groups and (b) a multifunctional compound that comprises functional groups that are reactive with the reactive end groups of the reactive multi-arm polymer. Also described herein are systems and methods that are based on such materials.Type: ApplicationFiled: February 2, 2021Publication date: August 5, 2021Inventors: Joseph T. Delaney, Jr., Mark W. Boden, John Murphy, Viktoria Molnar, Tatyana Dyndikova, Allison Zipp, Kolbein K Kolste
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Publication number: 20210060183Abstract: In some aspects, the present disclosure pertains to a polymer that comprises a plurality of polymer arms, wherein a first portion of the polymer arms comprise a reactive end group and wherein a second portion of the polymer arms comprise a branched end group that comprise a plurality of covalently attached diagnostic and/or therapeutic groups, which may be, for example, radiocontrast groups or radioactive groups. Other aspects pertain to a system that comprises (a) a first composition comprising such a polymer and (b) a second composition comprising a multifunctional compound that comprises reactive functional groups that are reactive with the reactive end group of the multi-arm polymer. Still other aspects pertain to a crosslinked reaction product of (a) such a polymer and (b) a multifunctional compound that comprises functional groups that are reactive with the reactive end group of the multi-arm polymer.Type: ApplicationFiled: August 21, 2020Publication date: March 4, 2021Inventors: Joseph T. Delaney, JR., Kolbein K. Kolste, Tatyana Dyndikova