Abstract: In one embodiment, a catheter apparatus is configured to be inserted into a body part of a living subject, and including an elongated deflectable element including a distal end, an expandable basket assembly disposed at the distal end and comprising a plurality of splines and a plurality of electrodes disposed on the splines, an irrigation channel disposed in the elongated deflectable element, and an inflatable balloon disposed in the expandable basket assembly and including a plurality of irrigation holes in fluid connection with the irrigation channel.

Abstract: The present disclosure relates to a drawing device for creating a pattern, wherein the drawing device comprises a gear assembly that rotates upon movement of the device, the gear assembly being operatively coupled to a cam and a cam follower, such that rotation of the gear assembly rotates the cam and causes the cam to bear against the cam follower. Movement of the cam follower thereby causes lateral movement of a marker carriage housing at least one writing instrument.

Abstract: A strengthened cover glass or glass-ceramic sheet or article as well as processes and systems for making the strengthened glass or glass-ceramic sheet or article is provided for use in consumer electronic devices. The process comprises cooling the cover glass sheet by non-contact thermal conduction for sufficiently long to fix a surface compression and central tension of the sheet. The process results in thermally strengthened cover glass sheets for use in or on consumer electronic products.

Abstract: The system and method for characterizing a tissue of interest may include navigating a needle device in proximity to the tissue of interest. The needle device can comprise a member including a plurality of electroconductive segments. The plurality of electroconductive segments can be electrically insulated from one another. The device can also include a first conductive path electrically coupled to a first electroconductive segment. A second conductive path can be coupled to a second electroconductive segment. The method can include contacting the tissue of interest with the first electrode and determining a tissue impedance of the tissue of interest from an electrical signal from the first electrode. The method can also include characterizing the tissue of interest as malignant or benign based on the tissue impedance.

Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, thereof: which inhibit the cellular entry of hepatitis B virus (HBV) and/or hepatitis D virus (HDV) or interfere with the function of the life cycle of HBV and/or HDV and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HBV and/or HDV infection. The invention also relates to methods of treating an HBV and/or HDV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

Abstract: The present disclosure is generally directed to an anucleated cell-based platforms for encapsulation and delivery of agricultural compounds. Disclosed herein are compositions for the stable and targeted delivery of agricultural compounds within achromosomal and/or anucleated cells. The present disclosure also provides methods of improving encapsulation and retention of agricultural compounds in achromosomal and/or anucleated cells.

Abstract: Systems for producing articles from glass tube include a converter having a base with a plurality of processing stations and a turret moveable relative to the base. The turret indexes a plurality of holders for holding the glass tubes successively through the processing stations. The systems further include a gas flow system or a suction system for producing a flow of gas through the glass tube during one or more heating, forming, separating or piercing operations. The flow of gas through the glass tube produced by the gas flow system or suction system may be sufficient to evacuate or purge volatile constituents of the glass from the glass tube and/or pierce a meniscus formed on the glass tube during separation, thereby reducing the Surface Hydrolytic Response (SHR) of the interior surface of the glass tube and articles made therefrom.

Abstract: A bone material dispensing system is provided. The bone material dispensing system comprises a loading device having a perimeter surrounding a base plane and a rim, the perimeter comprising a side wall extending along a longitudinal axis and a bar joining the side wall at a corner of the perimeter and extending in a direction transverse to the longitudinal axis, the base plane comprising a loading surface bordered by the side wall along the longitudinal axis, the loading surface having an end edge extending in a direction transverse to the longitudinal axis such that the side wall, the bar and the end edge form a rim adjacent to the loading surface and the bar. A method of loading bone material with the bone material dispensing system is also provided.

Abstract: An excess flow valve (EFV) is disclosed that has an efficient and durable construction. The EFV is efficient in terms of both size and cost. It is durable partly due to a design with few parts and also because of optional all metal construction. In some embodiments, an intumescent material is included that expands to close off the valve by pressing the valve plug into sealing engagement with the valve seat and permanently stopping the flow of gas when a pressure differential or flow velocity threshold is exceeded.

Abstract: The present disclosure is generally directed to an agricultural formulation comprising an anucleated minicells and an anucleated cell-based platforms for encapsulation and scalable delivery of biologically active compounds. Disclosed herein are compositions for the stable and targeted delivery of biologically active compounds within achromosomal and/or anucleated cells onto and/or into a target cell. The present disclosure also provides methods of improving encapsulation and retention of biologically active compounds in achromosomal and/or anucleated cells and delivering biologically active compounds into a target cell.

Abstract: Disclosed herein are glass pharmaceutical vials having sidewalls of reduced thickness. In embodiments, the glass pharmaceutical vial may include a glass body comprising a sidewall enclosing an interior volume. An outer diameter D of the glass body is equal to a diameter d1 of a glass vial of size X as defined by ISO 8362-1, wherein X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1. However, the sidewall of the glass pharmaceutical vial comprises an average wall thickness Ti that is less than or equal to 0.85*s1, wherein s1 is a wall thickness of the glass vial of size X as defined by ISO 8362-1 and X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1.

Abstract: Disclosed herein are glass pharmaceutical vials having sidewalls of reduced thickness. In embodiments, the glass pharmaceutical vial may include a glass body comprising a sidewall enclosing an interior volume. An outer diameter D of the glass body is equal to a diameter d1 of a glass vial of size X as defined by ISO 8362-1, wherein X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1. However, the sidewall of the glass pharmaceutical vial comprises an average wall thickness Ti that is less than or equal to 0.85*s1, wherein s1 is a wall thickness of the glass vial of size X as defined by ISO 8362-1 and X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1.

Abstract: Integrated multiple actuator electro-hydraulic systems as well as their methods of use are described. Depending on the particular application, the integrated electro-hydraulic systems may exhibit different frequency responses and/or may be integrated into a single combined unit.

Abstract: Disclosed herein are hydraulic actuators and methods for the operation of actuators having variable relative pressure ratios. Further disclosed are methods for designing and/or operating a hydraulic actuator such that the actuator exhibits a variable relative pressure ratio. In certain embodiments, the relative pressure ratio of the hydraulic actuator may be dependent on one or more characteristics (such as, for example, frequency or rate of change) of an oscillating input to the hydraulic actuator.

Abstract: A bearing module that supports adjacent ends of coaxial shafts, includes an outer ring having first and second axially adjacent raceways and first and second flanges located at the respective ends. A first group of rolling elements rolls on the first raceway, and a second group of rolling elements rolls on the second raceway. A first cage retains the first group of rolling elements circumferentially spaced apart from one another, and a second cage retains the second group of rolling elements. An axial bearing is retained axially between the first and second groups of rolling elements, and has axial bearing rolling elements that are configured for rolling contact with (a) facing axial side raceways on first and second inner rings supported respectively on the first and second groups of rolling elements, (b) the adjacent ends of the two coaxial shafts, or (c) integral washers of the axial bearing.

Abstract: An iron-air battery including an iron electrode in contact with an anode current collector, wherein the iron electrode includes a plurality of channels; an oxygen reduction reaction electrode having a first surface facing the plurality of channels and an opposing second surface in contact with air; an oxygen evolution reaction electrode interdigitated with the plurality of channels of the iron electrode, wherein at least a portion of the oxygen evolution reaction electrode is disposed within the plurality of channels in a direction perpendicular to a plane of the oxygen reduction reaction electrode; and an electrolyte in contact with the iron electrode, the first surface of the oxygen reduction reaction electrode, the plurality of channels, and the oxygen evolution reaction electrode.

Abstract: Some embodiments of the disclosure include inventive compounds (e.g., compounds of Formula (I)) and compositions (e.g., pharmaceutical compositions) which inhibit IRAK and/or FLT3 and which can be used for treating, for example, certain diseases. Some embodiments include methods of using the inventive compound (e.g., in compositions or in pharmaceutical compositions) for administering and treating (e.g., diseases such as hematopoietic cancers, myelodysplastic syndromes (MDS), acute myeloid leukemia (AML), etc.), Additional embodiments provide disease treatment using combinations of the inventive IRAK and/or FLT3 inhibiting compounds with other therapies, such as cancer therapies.

Abstract: In some aspects, the present disclosure pertains to a system for forming a radiopaque product that comprises an iodinated compound comprising one or more diene containing moieties and a multi-arm polymer comprising a plurality of dienophile containing moieties, wherein the diene containing moieties of the iodinated compound couple with the dienophile containing moieties of the multi-arm polymer through a Diels-Alder reaction. Other aspects of the disclosure pertain to crosslinked networks that are formed by combining such an iodinated compound with such a multi-arm polymer, whereupon the diene containing moieties couple with the dienophile containing moieties through a Diels-Alder reaction.

Abstract: Components for articles of footwear and athletic equipment including a foam are provided. The foam portion of the components and articles include a composition which includes a thermoplastic copolyester, the composition having a foam structure. A polymer layer is provided on at least on surface of the foam portion. The polymer layer can control or reduce the water uptake of the foam portion. Methods of making the compositions, foams, and components are provided, as well as methods of making an article of footwear including one of the foam components. In some aspects, the foams and foam components can be made by injection molding, or injection molding followed by compression molding.

Abstract: A stator vane assembly for a compressor of an aircraft turbine engine includes an inner shroud, an outer shroud and stator vanes. The stator vanes are attached only to the inner shroud and are in non-immobilizing mechanical contact with the outer shroud.