Patents by Inventor Joseph W. Burns

Joseph W. Burns has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TRICYCLIC UREA COMPOUNDS AS JAK2 V617F INHIBITORS
    Publication number: 20240150354
    Abstract: The present application provides tricyclic urea compounds that modulate the activity of the V617F variant of JAK2, which are useful in the treatment of various diseases, including cancer.
    Type: Application
    Filed: August 24, 2023
    Publication date: May 9, 2024
    Inventors: Yanran Ai, Onur Atasoylu, Yu Bai, Joseph Barbosa, David M. Burns, Daniel Levy, Brent Douty, Hao Feng, Leah C. Konkol, Cheng-Tsung Lai, Xun Liu, Song Mei, Jun Pan, Haisheng Wang, Liangxing Wu, Wenqing Yao, Eddy W. Yue
  • Automated polysomnographic assessment for rapid eye movement sleep behavior disorder
    Patent number: 7996076
    Abstract: Methods and systems for diagnosing or assessing rapid eye movement sleep behavior disorder (RBD). Muscle tone or activity variance during rapid eye movement (REM) and non-rapid eye movement (NREM) sleep intervals of a polysomnogram are compared. A threshold based on the NREM data is used to identify a subject-specific threshold for abnormality in the REM variance. A metric that includes the percentage of REM variance exceeding the threshold relates to RBD.
    Type: Grant
    Filed: April 2, 2008
    Date of Patent: August 9, 2011
    Assignees: The Regents of the University of Michigan, Michigan Technological University
    Inventors: Joseph W. Burns, Ronald D. Chervin
  • Automated polysomnographic assessment for rapid eye movement sleep behavior disorder
    Publication number: 20080262373
    Abstract: Methods and systems for diagnosing or assessing rapid eye movement sleep behavior disorder (RBD). Muscle tone or activity variance during rapid eye movement (REM) and non-rapid eye movement (NREM) sleep intervals of a polysomnogram are compared. A threshold based on the NREM data is used to identify a subject-specific threshold for abnormality in the REM variance. A metric that includes the percentage of REM variance exceeding the threshold relates to RBD.
    Type: Application
    Filed: April 2, 2008
    Publication date: October 23, 2008
    Inventors: Joseph W. Burns, Ronald D. Chervin
  • System and method for analysis of respiratory cycle-related EEG changes in sleep-disordered breathing
    Patent number: 7190995
    Abstract: A system and method for determining respiratory cycle-related EEG changes (RCREC) for a subject with sleep-disordered breathing are provided. The method includes receiving an EEG signal from the subject using at least one sensor, and defining at least two respiratory cycle segments within each respiratory cycle. The method further includes determining an EEG power of the EEG signal during each of the at least two respiratory cycle segments, and determining RCREC by calculating a difference between a maximum EEG segment power and a minimum EEG segment power.
    Type: Grant
    Filed: June 14, 2004
    Date of Patent: March 13, 2007
    Assignees: The Regents of the University of Michigan, Altarum Institute
    Inventors: Ronald D. Chervin, Joseph W. Burns, Nikolas S. Subotic, Christopher Roussi
  • System and method for analysis of respiratory cycle-related EEG changes in sleep-disordered breathing
    Publication number: 20040254493
    Abstract: A system and method for determining respiratory cycle-related EEG changes (RCREC) for a subject with sleep-disordered breathing are provided. The method includes receiving an EEG signal from the subject using at least one sensor, and defining at least two respiratory cycle segments within each respiratory cycle. The method further includes determining an EEG power of the EEG signal during each of the at least two respiratory cycle segments, and determining RCREC by calculating a difference between a maximum EEG segment power and a minimum EEG segment power.
    Type: Application
    Filed: June 14, 2004
    Publication date: December 16, 2004
    Applicants: The Regents of the University of Michigan, Altarum Institute
    Inventors: Ronald D. Chervin, Joseph W. Burns, Nikolas S. Subotic, Christopher Roussi