Patents by Inventor Joseph W. Sassani

Joseph W. Sassani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for treatment of epithelial wounds
    Patent number: 9974783
    Abstract: The invention relates to treatment of epithelial wounds. In particular, the invention relates to methods and formulations for treating epithelial wounds based on application of an opioid antagonist such as naltrexone.
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: May 22, 2018
    Assignee: The Penn State Research Foundation
    Inventors: Ian S. Zagon, Patricia J. McLaughlin, Joseph W. Sassani
  • METHODS AND COMPOSITIONS FOR TREATMENT OF DERMAL AND EPIDERMAL WOUNDS
    Publication number: 20180055838
    Abstract: This disclosure relates to compositions and methods for the treatment of dermal and epidermal wounds. In particular, the disclosure relates to treating dermal and epidermal wounds based on application of a composition comprising an opioid receptor antagonist, a pharmaceutically acceptable carrier, and an enkephalinase. In some cases, the enkephalinase comprises aminopeptidase N (APN), neprilysin, dipeptidyl peptidase 3 (DPP3), carboxypeptidase A6 (CPA6), leucyl/cystinyl aminopeptidase (LNPEP), angiotensin-converting enzyme (ACE), endothelin-converting enzyme-2 (ECE-2), a peroxin (PEX), damage induced neuronal endopeptidase (DINE), Kell protein, or a combination thereof.
    Type: Application
    Filed: October 31, 2017
    Publication date: March 1, 2018
    Inventors: Ian S. ZAGON, Patricia J. MCLAUGHLIN, Joseph W. SASSANI
  • METHODS AND COMPOSITIONS FOR TREATMENT OF EPITHELIAL WOUNDS
    Publication number: 20160250206
    Abstract: The invention relates to treatment of epithelial wounds. In particular, the invention relates to methods and formulations for treating epithelial wounds based on application of an opioid antagonist such as naltrexone.
    Type: Application
    Filed: March 11, 2016
    Publication date: September 1, 2016
    Inventors: Ian S. ZAGON, Patricia J. MCLAUGHLIN, Joseph W. SASSANI
  • Methods and compositions for treatment of epithelial wounds
    Patent number: 9283175
    Abstract: This invention relates to treatment of epithelial wounds. In particular, the invention relates to methods and formulations for treating epithelial wounds based on application of an opioid antagonist such as naltrexone.
    Type: Grant
    Filed: July 26, 2012
    Date of Patent: March 15, 2016
    Inventors: Ian S. Zagon, Patricia J. McLaughlin, Joseph W. Sassani
  • METHODS AND COMPOSITIONS FOR TREATMENT OF EPITHELIAL WOUNDS
    Publication number: 20140171460
    Abstract: This invention relates to treatment of epithelial wounds. In particular, the invention relates to methods and formulations for treating epithelial wounds based on application of an opioid antagonist such as naltrexone.
    Type: Application
    Filed: July 26, 2012
    Publication date: June 19, 2014
    Inventors: Ian S. Zagon, Patricia J. Mclaughlin, Joseph W. Sassani
  • Methods and compositions for treating dry eye
    Patent number: 8314118
    Abstract: This invention relates to treatment of dry eye. In particular, the invention relates to methods and formulations for treating dry eye based on topical application of opioid antagonists such as naltrexone.
    Type: Grant
    Filed: April 15, 2010
    Date of Patent: November 20, 2012
    Inventors: Ian S. Zagon, Patricia J. McLaughlin, Joseph W. Sassani
  • METHODS AND COMPOSITIONS FOR TREATING DRY EYE
    Publication number: 20100273821
    Abstract: This invention relates to treatment of dry eye. In particular, the invention relates to methods and formulations for treating dry eye based on topical application of opioid antagonists such as naltrexone.
    Type: Application
    Filed: April 15, 2010
    Publication date: October 28, 2010
    Inventors: Ian S. Zagon, Patricia J. McLaughlin, Joseph W. Sassani