Patents by Inventor Josephine Juettner

Josephine Juettner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYNP1, A PROMOTER FOR THE SPECIFIC EXPRESSION OF GENES IN INTERNEURONS
    Publication number: 20190376083
    Abstract: The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 1000 bp having at least 80% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in interneurons of a gene when operatively linked to a nucleic acid sequence coding for said gene.
    Type: Application
    Filed: November 29, 2017
    Publication date: December 12, 2019
    Inventors: Josephine JUETTNER, Botond ROSKA, Miguel TEIXEIRA
  • SYNP107, A PROMOTER FOR THE SPECIFIC EXPRESSION OF GENES IN INTERNEURONS
    Publication number: 20190376082
    Abstract: The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 700 bp having at least 80% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in interneurons of a gene when operatively linked to a nucleic acid sequence coding for said gene.
    Type: Application
    Filed: November 29, 2017
    Publication date: December 12, 2019
    Inventors: Josephine JUETTNER, Botond ROSKA, Miguel TEIXEIRA
  • SynP198, a promoter for the specific expression of genes in direction selective retinal ganglion cells
    Publication number: 20190276847
    Abstract: The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 400 bp having at least 80% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in direction selective retinal ganglion cells of a gene when operatively linked to a nucleic acid sequence coding for said gene.
    Type: Application
    Filed: November 1, 2017
    Publication date: September 12, 2019
    Inventors: Dominik HARTL, Josephine JUETTNER, Arnaud KREBS, Botond ROSKA, Dirk SCHUEBELER
  • SYNP161, A PROMOTER FOR THE SPECIFIC EXPRESSION OF GENES IN ROD PHOTORECEPTORS
    Publication number: 20190054191
    Abstract: The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 150 bp having at least 80% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in rod photoreceptors of a gene when operatively linked to a nucleic acid sequence coding for said gene.
    Type: Application
    Filed: December 1, 2016
    Publication date: February 21, 2019
    Applicant: Friedrich Miescher Institute for Biomedical Research
    Inventors: Dominik HARTL, Josephine JUETTNER, Arnaud KREBS, Botond ROSKA, Dirk SCHUEBELER
  • Muller cell-specific promoter
    Patent number: 10179917
    Abstract: The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 400 bp having at least 80% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in Muller cells of a gene when operatively linked to a nucleic acid sequence coding for said gene.
    Type: Grant
    Filed: February 10, 2015
    Date of Patent: January 15, 2019
    Assignee: FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH
    Inventors: Botond Roska, Josephine Juettner
  • SYNP159, A PROMOTER FOR THE SPECIFIC EXPRESSION OF GENES IN ROD PHOTORECEPTORS
    Publication number: 20180355377
    Abstract: The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 400 bp having at least 80% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in rod photoreceptors of a gene when operatively linked to a nucleic acid sequence coding for said gene.
    Type: Application
    Filed: December 1, 2016
    Publication date: December 13, 2018
    Applicant: Friedrich Miescher Institute for Biomedical Research
    Inventors: Dominik HARTL, Josephine JUETTNER, Arnaud KREBS, Botond ROSKA, Dirk SCHUEBELER
  • SYNP160, A PROMOTER FOR THE SPECIFIC EXPRESSION OF GENES IN ROD PHOTORECEPTORS
    Publication number: 20180353617
    Abstract: The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 300 bp having at least 80% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in rod photoreceptors of a gene when operatively linked to a nucleic acid sequence coding for said gene.
    Type: Application
    Filed: December 1, 2016
    Publication date: December 13, 2018
    Applicant: Friedrich Miescher Institute for Biomedical Research
    Inventors: Dominik HARTL, Josephine JUETTNER, Arnaud KREBS, Botond ROSKA, Dirk SCHUEBELER
  • SYNP162, A PROMOTER FOR THE SPECIFIC EXPRESSION OF GENES IN ROD PHOTORECEPTORS
    Publication number: 20180346529
    Abstract: The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 300 bp having at least 80% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in rod photoreceptors of a gene when operatively linked to a nucleic acid sequence coding for said gene.
    Type: Application
    Filed: December 1, 2016
    Publication date: December 6, 2018
    Applicant: Friedrich Miescher Institute for Biomedical Research
    Inventors: Dominik HARTL, Josephine JUETTNER, Arnaud KREBS, Botond ROSKA, Dirk SCHUEBELER
  • PROMOTER FOR THE SPECIFIC EXPRESSION OF GENES IN RETINAL ENDOTHELIAL CELLS
    Publication number: 20180298378
    Abstract: The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 600 bp having at least 80% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in retinal endothelial cells of a gene when operatively linked to a nucleic acid sequence coding for said gene.
    Type: Application
    Filed: October 13, 2016
    Publication date: October 18, 2018
    Applicant: Friedrich Miescher Institute for Biomedical Research
    Inventors: Josephine JUETTNER, Botond ROSKA
  • NOVEL THERAPEUTICAL TOOLS AND METHODS FOR TREATING BLINDNESS BY TARGETING PHOTORECEPTORS
    Publication number: 20180256753
    Abstract: The present invention relates to an isolated nucleic acid molecule comprising a nucleotide sequence coding for a depolarizing light-gated ion channel functionally linked to a promoter leading to the specific expression of said depolarizing light-gated ion channel in a retinal photoreceptor, or the nucleotide sequence complementary to said nucleotide sequence, for use in treating or ameliorating blindness. The present invention also relates to methods of using such nucleic acid molecules in the treatment of blindness.
    Type: Application
    Filed: September 13, 2016
    Publication date: September 13, 2018
    Applicant: Friedrich Miescher Institute for Biomedical Research
    Inventors: Josephine JUETTNER, Dasha NELIDOVA, Botond ROSKA
  • AII retinal amacrine cell-specific promoter
    Patent number: 9999685
    Abstract: The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO: 1 or a nucleic acid sequence of at least 200 bp having at least 70% identity to the sequence of SEQ ID NO: 1, wherein the isolated nucleic acid molecule specifically leads to the expression in retinal amacrine bipolar cells of a gene when operatively linked to a nucleic acid sequence coding for the gene.
    Type: Grant
    Filed: February 9, 2015
    Date of Patent: June 19, 2018
    Assignee: FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH
    Inventors: Botond Roska, Josephine Juettner
  • PROMOTER FOR THE SPECIFIC EXPRESSION OF GENES IN MÜLLER CELLS
    Publication number: 20180127778
    Abstract: The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 400 bp having at least 80% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in Müller cells of a gene when operatively linked to a nucleic acid sequence coding for said gene.
    Type: Application
    Filed: April 29, 2016
    Publication date: May 10, 2018
    Inventors: Botond BOSKA, Josephine JUETTNER
  • AII RETINAL AMACRINE CELL-SPECIFIC PROMOTER
    Publication number: 20170119905
    Abstract: The present invention provides an isolated nucleic acid molecule comprising, or consisting of the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 200 by having at least 70% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in retinal amacrine bipolar cells of a gene when operatively linked to a nucleic acid sequence coding for said gene.
    Type: Application
    Filed: February 9, 2015
    Publication date: May 4, 2017
    Applicant: Friedrich Miesher Institute for Biomedical Research
    Inventors: Botond ROSKA, Josephine JUETTNER
  • Retinal OFF circuit-specific promoter
    Patent number: 9579399
    Abstract: The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 200 bp having at least 70% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in cones and/or OFF bipolar cells of a gene when operatively linked to a nucleic acid sequence coding for said gene.
    Type: Grant
    Filed: August 26, 2013
    Date of Patent: February 28, 2017
    Assignee: FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH
    Inventors: Botond Roska, Josephine Juettner
  • MULLER CELL-SPECIFIC PROMOTER
    Publication number: 20170022520
    Abstract: The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 400 bp having at least 80% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in Muller cells of a gene when operatively linked to a nucleic acid sequence coding for said gene.
    Type: Application
    Filed: February 10, 2015
    Publication date: January 26, 2017
    Inventors: Botond ROSKA, Josephine JUETTNER
  • Retinal OFF circuit-specific promoter
    Publication number: 20150344907
    Abstract: The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 200 bp having at least 70% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in cones and/or OFF bipolar cells of a gene when operatively linked to a nucleic acid sequence coding for said gene.
    Type: Application
    Filed: August 26, 2013
    Publication date: December 3, 2015
    Applicant: FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH
    Inventors: Botond ROSKA, Josephine JUETTNER
  • Rod cell-specific promoter
    Publication number: 20140287510
    Abstract: The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 200 bp having at least 70% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in rod cells of a gene when operatively linked to a nucleic acid sequence coding for said gene.
    Type: Application
    Filed: November 7, 2012
    Publication date: September 25, 2014
    Applicant: NOVARTIS FORSCHUNGSSTIFTUNG, ZWEIGNIEDERLASSUNG FRIEDRICH MIESCHER INSTITUTE
    Inventors: Sandra Siegert, Josephine Juettner, Botond Roska