Abstract: The present disclosure provides methods and diagnostic tools comprising classifiers and indicator cells that respond differentially to a sample derived from a subject having a disease or cancer, such as lung cancer, as compared to a control or normal sample. Also disclosed herein are methods of detecting a multicomponent gene expression readout from a genetically identical population of cells.

Abstract: Systems and methods for determining vehicle vocation are provided. The method involves operating at least one processor to: retrieve telematics data associated with a vehicle, the telematics data originating from a telematics device installed in the vehicle; process the telematics data to extract a plurality of feature datasets, the plurality of feature datasets including: a first dataset associated with distances traveled by the vehicle; a second dataset associated with stops completed by the vehicle; and a third dataset associated with round trips performed by the vehicle; apply a plurality of trained cluster models to the plurality of feature datasets to determine a plurality of vocation probabilities; and determine the vocation of the vehicle based on the plurality of vocation probabilities.

Abstract: This invention relates to a core for hollow door manufacture comprising a method whereby the mechanical arrangement of the core glue applicators produces multi sized closed cell filler material once severed and expanded wherein a combination of both contracting and expanding cells presents as a centrally aligned column of contracting cells while other cells expand utilizing adhesively affixed non rigid flexible single face corrugated material.

Abstract: The invention provides a method to detect an abnormal condition or disease state by assessing a characteristic response pattern of responder cells to indicators contained in a biological fluid of a subject. A characteristic disease-associated pattern can be obtained by determining the response pattern of responder cells to that of bodily fluids or fractions thereof from subjects known to exhibit a particular abnormal condition optionally comparing said pattern to such pattern elicited by fluids or fractions from normal subjects and identifying elements that differ. The identified elements constitute a characteristic or differential pattern which can then be used to identify the presence or stage of a disease in a test subject.

Abstract: Methods to detect amyotrophic lateral sclerosis (ALS) or presymptomatic Alzheimer's disease (PSAD) using an indicator cell assay platform (iCAP) in a test subject are described. Specifically, the disclosure provides a method comprising contacting a biological fluid of said test subject with indicator cells and assessing said indicator cells for the level of expression of an exon of CKIgamma2 that encodes the C-terminal palmitoylated region of said CKIgamma2, to determine the probability that a test subject is afflicted with amyotrophic lateral sclerosis (ALS). Further disclosed are methods of using indicator cells that are pan neuronal populations of glutamatergic (and/or GABAergic) neurons to determine the probability of the presence of presymptomatic or symptomatic Alzheimer's disease (PSAD) in a test subject.

Abstract: Implementations of a method for treating an affected area of an epidermis having a blister or rash caused by shingles, psoriasis, acne, eczema, bug bits, bee stings, and poison oak comprising applying topically to the affected area of an epidermis a composition comprises eugenol and sesame oil.

Abstract: Dispensing units for dispensing items, such as in a healthcare facility, are linked in a network. The dispensing units use a fingerprint to authenticate users. The fingerprints on a short list reflect recent authorization, and permit access without other identifying information. Dispensing units in the network may use different fingerprint scanning technologies, but are made compatible by enrolling fingerprints using the different technologies. Two or more reference fingerprints may be stored at a dispensing unit, permitting either a primary fingerprint or alternate fingerprint to gain access to that dispensing unit. During enrollment of a user, fingerprints for a user may be “fast tracked” for registration based upon a quality determination.

Abstract: The invention provides a method to detect an abnormal condition or disease state by assessing a characteristic response pattern of responder cells to indicators contained in a biological fluid of a subject. A characteristic disease-associated pattern can be obtained by determining the response pattern of responder cells to that of bodily fluids or fractions thereof from subjects known to exhibit a particular abnormal condition optionally comparing said pattern to such pattern elicited by fluids or fractions from normal subjects and identifying elements that differ. The identified elements constitute a characteristic or differential pattern which can then be used to identify the presence or stage of a disease in a test subject.

Abstract: A service multiplexer (2) for connecting a plurality of signal sources to a public switched communication network transfers data in the form of a synchronously transferred data cells from a plurality of inputs (4) to an output (6) for connection to the network. The multiplexer (2) includes a bandwidth control unit which receives a bandwidth control signal from the network representative of available bandwidth for transmission of cells to the network and generates feedback control signals for transmission to the signal sources to cause them to alter their data transmission rates in accordance with the available bandwidth. An activity detector coupled to the bandwidth control unit monitors the bandwidth of data received at the inputs. The multiplexer allows ABR (available bit rate)—commandable signal sources to be linked to a single port of a public network operating on an ABR basis to provide an efficient and fair allocation of bandwidth for each source.

Abstract: A network for ATM signals includes source end systems SES1, SES3 connected by a permanent virtual connection PVC1 through switch SW1 . . . SWN. Dynamic bandwidth controllers DBC1, DBC2 operate as virtual source/virtual destinations. The individual switches, such as switch SW2 have associated rate controllers RC1 which determine the available bandwidth for the signal path PVC1. Dynamic bandwidth controller DBC1 interrogates the rate controller RC1, RC2 using resource management RM signals which cascade from switching node to switching node along the path in a forward direction and then in a backward direction. The DBC's communicate with the SES's using RM signals which may be of a different format to the RM signals which pass from switching node to switching node.

Abstract: A broadband switching system and method switches asynchronously transferred cells of data using a dynamic bandwidth controller to control application of data cells from a number of transmitting end systems to an input port of the system. The dynamic bandwidth controller provides cell buffering from each source and controls output of data cells to the system according to a current cell rate assigned to cells from the respective end system. When an end system begins transmitting data cells, the controller detects the presence of incoming cells and requests bandwidth from a connection admission control forming part of the system. A default cell rate is provided for the end system so that transmission can continue until an appropriate bandwidth is allocated. The controller contains a buffer for buffering cells in this situation.