Patents by Inventor Joyce A. Sutcliffe

Joyce A. Sutcliffe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bifunctional heterocyclic compounds and methods of making and using same
    Publication number: 20050197334
    Abstract: The invention provides a family of bifunctional heterocyclic compounds useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. The invention also provides methods of making the bifunctional heterocyclic compounds, and methods of using such compounds as anti-infective, anti-proliferative agents, anti-inflammatory, and/or prokinetic agents.
    Type: Application
    Filed: September 25, 2003
    Publication date: September 8, 2005
    Inventors: Deping Wang, Joyce Sutcliffe, Adegboyega Oyelere, Timothy McConnell, Joseph Ippolito, John Abelson, Dane M. Springer, Joseph M. Salvino, Rongliang Lou, Joel A. Goldberg, Jay J. Farmer, Erin M. Duffy, Ashoke Bhattacharjee
  • RIBOSOME STRUCTURE AND PROTEIN SYNTHESIS INHIBITORS
    Publication number: 20050036997
    Abstract: The invention provides methods for producing high resolution crystals of ribosomes and ribosomal subunits as well as crystals produced by such methods. The invention also provides high resolution structures of ribosomal subunits either alone or in combination with protein synthesis inhibitors. The invention provides methods for identifying ribosome-related ligands and methods for designing ligands with specific ribosome-binding properties as well as ligands that may act as protein synthesis inhibitors. Thus, the methods and compositions of the invention may be used to produce ligands that are designed to specifically kill or inhibit the growth of any target organism.
    Type: Application
    Filed: August 2, 2002
    Publication date: February 17, 2005
    Applicants: Yale University, Rib-X Pharmaceuticals, Inc.
    Inventors: Thomas Steitz, Peter Moore, Joyce Sutcliffe, Adegboyega Oyelere, Joseph Ippolito
  • Use of heteroaryl substituted N-(indole-2-carbonyl-) amides for treatment of infection
    Patent number: 6555569
    Abstract: A pharmaceutical composition containing a glycogen phosphorylase inhibitor of Formula I or IA as defined herein is administered to a mammal to treat infection.
    Type: Grant
    Filed: February 16, 2001
    Date of Patent: April 29, 2003
    Assignee: Pfizer Inc.
    Inventors: Joyce A. Sutcliffe, Judith Lee Treadway
  • Use of heteroaryl substituted N-(indole-2-carbonyl-) amides for treatment of infection
    Publication number: 20010046985
    Abstract: A pharmaceutical composition containing a glycogen phosphorylase inhibitor of Formula I or IA as defined herein is administered to a mammal to treat infection.
    Type: Application
    Filed: February 16, 2001
    Publication date: November 29, 2001
    Inventors: Joyce A. Sutcliffe, Judith Lee Treadway
  • 4-hydroxy coumarin derivatives
    Patent number: 5985912
    Abstract: Compounds of the formula The compounds are useful in the treatment of bacterial infections.
    Type: Grant
    Filed: September 18, 1998
    Date of Patent: November 16, 1999
    Assignee: Pfizer Inc.
    Inventors: Bingwei Yang, Joyce Sutcliffe, Chris J. Dutton
  • 4-hydroxy coumarin derivatives with antibacterial activity
    Patent number: 5624951
    Abstract: A compound of formula V: ##STR1## wherein all the R's groups are as defined in the specification, is useful in the treatment of bacterial infections.
    Type: Grant
    Filed: March 1, 1995
    Date of Patent: April 29, 1997
    Assignee: Pfizer Inc.
    Inventors: Bingwei Yang, Joyce Sutcliffe, Chris J. Dutton