Abstract: Learned workload synthesis is disclosed. In an aspect of the present disclosure, a time series dataset corresponding to a target workload is received. A set of performance characteristics is determined from the time series dataset. A call is provided to a prediction model to determine a candidate query sequence based on the determined set of performance characteristics. A synthetic workload is generated based on the determined candidate query sequence. A synthetic workload is generated based on the determined candidate query sequence. A first similarity between a first performance profile of the synthetic workload and a second performance profile of the target workload meets a workload performance threshold condition. A performance insight is determined based on the synthetic workload. In a further aspect, the prediction model is trained to predict performance profiles based on workload profiles generated by executing benchmark queries using hardware and/or software configurations.

Abstract: Compositions and methods for treating breast cancer. The disclosed peptides bind to EGFR and enhance the trafficking of EGFR to lysosomes for destruction. These peptides and small molecule analogs thereof can be used for treating cancer by reducing EGFR levels and/or by activating immune cells.

Abstract: Ingredient containers for use in a beverage carbonation system are provided. The ingredient container includes a container body defining an interior hollow chamber, and a cap coupled to the opening of the container body. The container body has an opening leading to the interior hollow chamber and a cross-section with a major axis defining a width that is greater than a minor axis defining a depth. The cap has an inlet that is sealed to retain fluid within the container and that is configured to open to allow gas to be injected into the interior hollow chamber. The cap has an outlet that is sealed to retain fluid within the container and that is configured to open to allow fluid within the container to flow out through the outlet valve. The inlet and the outlet are aligned along a first axis that extends parallel to the minor axis of the container body.

Abstract: A charger for an electronic nicotine delivery systems (“ENDS”) device, which may include aerosol delivery devices provides functionality for authentication, including age verification. Such devices may be restricted based on age or other factors that require some form of authentication, verification, and/or identification to satisfy the restriction. The accessory or charger may provide or connect with a verification system for confirming an age of a user. If the authentication or verification is not satisfied, the charger or accessory will not charge the device, rendering it unusable.

Abstract: One or more video gateway devices configured to: access pre-configured criteria including at least a first condition, a second condition, and a first event; access video content captured by cameras configured to capture video of areas of a manufacturing facility; determine, based on an analysis of the video content, that the first condition is satisfied; access sensor data from one or more sensors; determine, based on an analysis of the sensor data, that the second condition is satisfied; and based on determining that the first and second conditions are satisfied, cause the first event to be executed.

Abstract: A data dictionary generation system automatically populates and updates a data dictionary for listings offering shared data. A data dictionary includes metadata describing the shared data, including the individual objects, such as the individual tables, schemas, views, and functions. The shared data and each individual data object may be described in the data dictionary by a set of data fields that corresponds to the shared dataset or the object type of the individual object. The data dictionary can be presented to data consumers along with the description of the listing to provide data consumers with a comprehensive description of the shared data provided by a listing, including a high-level summary of the shared data and description of each individual object included in the shared data. The data dictionary allows data consumers to understand the contents of the shared data and how to use the shared data.

Abstract: Systems and methods are described for classification of interference for GNSS receivers. One or more neural networks are utilized to classify RF signal data received by a GNSS receiver. The classification associates the RF signal data with an RF environment. Appropriate interference mitigation techniques can be implemented by the receiver based on the classification.

Abstract: The present invention relates to processes for producing fermentation products from starch-containing material, wherein an alpha-amylase and optionally a thermostable protease, pullulanase and/or glucoamylase are present and/or added during liquefaction, wherein a cellulolytic composition is present and/or added during fermentation or simultaneous saccharification and fermentation. The invention also relates to a composition suitable for use in a process of the invention.

Abstract: A surgical stapling device includes a visualization device that extends through a body of the stapling device to facilitate visualization of tissue that surrounds an end effector of the stapling device. An anvil assembly of the surgical stapling device is adapted to facilitate passage of the visualization device through the anvil assembly.

Abstract: A lead autonomous vehicle (AV) includes a sensor configured to observe a field of view in front of the lead AV. Following AVs are on the same road behind the lead AV. A processor of the lead AV is configured to detect a road structural change on the particular road. The processor updates driving instructions of the lead AV to navigate through the structural change using driving instructions related to the structural change. The processor sends a first message to the operation server indicating that the structural change is detected. The operation server updates the first portion of the map data, reflecting the structural change. The operation server sends the updated map data to the one or more following AVs.

Abstract: Unsupervised object detection from lidar point clouds includes forecasting a set of new positions of a set of objects in a geographic region based on a first set of object tracks to obtain a set of forecasted object positions, and obtaining a new LiDAR point cloud of the geographic region. A detector model processes the new LiDAR point cloud to obtain a new set of bounding boxes around the set of objects detected in the new LiDAR point cloud. Object detection further includes matching the new set of bounding boxes to the set of forecasted object positions to generate a set of matches, updating the first set of object tracks with the new set of bounding boxes according to the set of matches to obtain an updated set of object tracks, and filtering, after updating, the updated set of object tracks to remove object tracks failing to satisfy a track length threshold, to generate a training set of object tracks.

Abstract: Disclosed herein are systems and methods for eardrum acoustic pressure estimation for hearing device applications. A receiver signal is produced through a receiver of a hearing device, or a physical extension of the receiver, placed inside an ear canal of a user. A microphone signal is sensed, in response to the receiver signal, using a microphone placed outside the ear canal. Based on the receiver signal and the microphone signal, a reliability signal of the microphone signal and a feedback-path signal are computed. A spectral representation signal of the feedback-path signal is computed, and a real-ear response signal is computed using a mathematical combination of the spectral-representation signal and the reliability signal. The computed real-ear response signal is used to modify an operational characteristic of the hearing device, or to make a recommendation for modification of an operational characteristic or a physical characteristic of the hearing device.

Abstract: Disclosed are Respiratory Syncytial Virus (RSV) antigens including a recombinant RSV F protein stabilized in a prefusion conformation. Also disclosed are nucleic acids encoding the antigens and methods of producing the antigens. Methods for generating an immune response in a subject are also disclosed. In some embodiments, the method is a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the antigen to the subject.

Abstract: A thermal management system for an aircraft comprises a first gas turbine engine, a first thermal bus, a first heat exchanger, and a chiller. The first thermal bus comprises a first heat transfer fluid, with the first heat transfer fluid being in fluid communication, in a closed loop flow sequence, between the first gas turbine engine, the first heat exchanger, and the chiller. Waste heat energy generated by the first gas turbine engine, is transferred to the first heat transfer fluid. The chiller is configured to lower a temperature of the first heat transfer fluid prior to the first heat transfer fluid being circulated through the gas turbine engine. The first heat exchanger is configured to transfer the waste heat energy from the first heat transfer fluid to a dissipation medium.

Abstract: A head-mounted display device includes a first set of one or more lenses and a first display configured to provide visual data through the first set of one or more lenses. The head-mounted display device further includes a first stepper motor mechanically coupled to the first display, and the first stepper motor is configured to move the first display along a first axis by rotating a rotatable component of the first stepper motor. The head-mounted display device further includes a first electronic controller configured to (i) determine a first position of the first display, (ii) receive information identifying a second position of the first display, and (iii) generate one or more electrical signals that cause the first stepper motor to move the first display from the first position to the second position along the first axis.

Abstract: A lower body garment with an integrated resistance band is an apparatus that provides constant resistance for the lower body of a user throughout a workout. The apparatus includes a lower body garment and a resistance band. The lower body garment covers the lower body of the user and positions the resistance band around the thighs. The resistance band applies resistance throughout each movement and position of the legs. The lower body garment may extend to the ankles, the knees, or just above the knees. The apparatus further includes an inner left piece and an inner right piece to completely surround and enclose the legs while positioned within both the lower body garment and the resistance band. The apparatus may further include a skirt portion in order to appear as if a user is only wearing a skirt or to further accent the lower body garment.

Abstract: A watershed autonomous robotic data recorder maps subsurface topography and obtains water quality data for bodies of water. The device is capable of fully autonomous, manual, or hybrid navigation and includes a modular hull design which enables customization to accommodate both large and small bodies of water. A tangle-proof propulsion system is provided, to propel the hull(s). A deployable sensor pod includes a water sensor for determining if the sensor pod is in water, a pressure sensor for determining depth of the sensor pod, and a plurality of sensors for measuring water conditions. An onboard controller operates a winch that raises and lowers the sensor pod while the controller and a GPS receiver log positions of the sensor pod. This three-dimensional environmental, physical and chemical water quality attribute data collection creates a digital twin of the body of water to establish a common data environment for water modeling and analysis.

Abstract: Methods and systems are configured to determine a semantic meaning for data and generate data processing rules based on the semantic meaning of the data. The semantic meaning includes syntactical or contextual meaning for the data that is determined, for example, by profiling, by the data processing system, values stored in a field included in data records of one or more datasets; applying, by the data processing system, one or more classifiers to the profiled values; identifying, based on applying the one or more classifiers, one or more attributes indicative of a logical or syntactical characteristic for the values of the field, with each of the one or more attributes having a respective confidence level that is based on an output of each of the one or more classifiers. The attributes are associated with the fields and are used for generating data processing rules and processing the data.

Abstract: Disclosed are methods and apparatuses for classifier evaluation. The evaluation involves constructing a ground truth refinement having a degree of error within specified bounds from a malware reference dataset as an approximate ground truth refinement. The evaluation further involves using the approximate ground truth refinement to determine at least one of: a lower bound on precision or an upper bound on recall and accuracy. The evaluation further involves evaluating a classifier by evaluating at least one of a classification method or clustering method by examining changes to the upper bound and/or the lower bound produced by the approximate ground truth refinement.