Patents by Inventor Juan C. Chachques

Juan C. Chachques has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of enhancing myogenesis by electrical stimulation
    Patent number: 7483749
    Abstract: The present invention provides a method for enhancing regeneration of the myocardium. The method comprises the steps of applying electrical stimulation to an injury site in the myocardium. The method can be used in combination with implantation of myogenic cells into the injury site. The electrical stimulation may be applied before or after the implantation.
    Type: Grant
    Filed: March 28, 2005
    Date of Patent: January 27, 2009
    Assignee: Bioheart, Inc.
    Inventors: Howard J. Leonhardt, Juan C. Chachques
  • Method of providing a dynamic cellular cardiac support
    Patent number: 7341062
    Abstract: The present invention provides a method for repairing damaged myocardium. The method comprises using a combination of cellular cardiomyoplasty and electrostimulation for myogenic predifferentiation of stem cells and to synchronize the contractions of the transplanted cells with the cardiac cells. The method comprises the steps of obtaining stem or myogenic cells from a donor, culturing and electrostimulating the isolated cells in vitro, and implanting the cells into the damaged myocardium.
    Type: Grant
    Filed: May 17, 2004
    Date of Patent: March 11, 2008
    Assignee: Bioheart, Inc.
    Inventors: Juan C. Chachques, Howard J. Leonhardt
  • Method of providing a dynamic cellular cardiac support
    Publication number: 20020124855
    Abstract: The present invention provides a method for repairing damaged myocardium. The method comprises using a combination of cellular cardiomyoplasty and electrostimulation to synchronize the contractions of the transplanted cells with the cardiac cells. The method comprises the steps of obtaining myogenic cells from a donor and implanting the myogenic cells into the damaged myocardium. Electrical stimulation can be applied to the cells in vitro during culturing of the cells, after implantation of the cells into the myocardium or both.
    Type: Application
    Filed: March 11, 2002
    Publication date: September 12, 2002
    Inventor: Juan C. Chachques
  • Method and apparatus including a sliding insulation lead for cardiac assistance
    Patent number: 4735205
    Abstract: A method and apparatus for providing muscle stimulation in the field of Function Electrical Stimulation, particularly electrical stimulation to a muscle employed as a myocardial substitute. The Latissimus Dorsi muscular flap is divided into two parts to cover the surfaces of the heart and inserted into a thoracic cavity by means of a segmental resection of the second rib. After or before positioning the muscle in this fashion, first and second stimulating electrodes are threaded into the muscle at desired locations to effect contraction of the muscle around the heart upon application of electrical stimulating pulses between the two electrodes. Stimulating pulses having suitable parameters chosen to effect the desired functional contraction of the muscle are generated in synchrony with natural or stimulated heart contractions.
    Type: Grant
    Filed: February 24, 1986
    Date of Patent: April 5, 1988
    Assignee: Medtronic, Inc.
    Inventors: Juan C. Chachques, Pierre A. Grandjean, Karel Smits