Patents by Inventor Juan Carlos Murciano

Juan Carlos Murciano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for prevention and treatment of uncontrolled formation of intravascular fibrin clots
    Patent number: 7837997
    Abstract: Compositions and methods for prevention and treatment of uncontrolled formation of intravascular fibrin clots are provided wherein fibrinolytic or anticoagulant drugs are biocompatibly coupled to red blood cell carriers.
    Type: Grant
    Filed: December 18, 2006
    Date of Patent: November 23, 2010
    Assignees: Trustees of the University of Pennsylvania, University of Virginia Patent Foundation
    Inventors: Vladimir R. Muzykantov, Abd Al-Roof Higazi, Juan Carlos Murciano, Douglas Cines, Ronald P. Taylor
  • Targeting and prolonging association of drugs to the luminal surface of the pulmonary vascular endothelial cells using antibodies that bind to ICAM-1
    Patent number: 7674466
    Abstract: Methods for targeting and prolonging association of a selected drug to the luminal surface of pulmonary vascular endothelium of an animal are provided wherein a selected drug is administered to an animal in combination with a non-internalizable ICAM-1 antibody which binds to an antigen on the luminal surface of the pulmonary vasculature. This method is particularly useful in dissolution of fibrin clots or prevention of the intravascular coagulation in the pulmonary vasculature.
    Type: Grant
    Filed: September 23, 2005
    Date of Patent: March 9, 2010
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Vladimir R. Muzykantov, Juan Carlos Murciano, D. Neil Granger
  • Compositions and methods for prevention and treatment of uncontrolled formation of intravascular fibrin clots
    Patent number: 7172760
    Abstract: Compositions and methods for prevention and treatment of uncontrolled formation of intravascular fibrin clots are provided wherein fibrinolytic or anticoagulant drugs are biocompatibly coupled to red blood cell carriers.
    Type: Grant
    Filed: September 23, 2002
    Date of Patent: February 6, 2007
    Assignees: Trustees of the University of Pennsylvania, University of Virginia Patent Foundation
    Inventors: Vladimir R. Muzykantov, Abd Al-Roof Higazi, Juan Carlos Murciano, Douglas Cines, Ronald P. Taylor
  • Compositions and methods for selective dissolution of nascent intravascular blood clots
    Patent number: 7041287
    Abstract: Compositions and methods for prevention and treatment of uncontrolled formation of intravascular fibrin clots, which are capable of selective dissolution of pathological nascent clots formed intravascularly, with minimal risk of unwanted dissolution of pre-existing hemostatic clots, are provided wherein fibrinolytic or anticoagulant drugs are biocompatibly coupled to red blood cell carriers.
    Type: Grant
    Filed: July 1, 2003
    Date of Patent: May 9, 2006
    Assignee: Trustees of the University of Pennsylvania
    Inventors: Vladimir R. Muzykantov, Juan Carlos Murciano, Douglas Cines
  • Compositions and methods for selective dissolution of nascent intravascular blood clots
    Publication number: 20040053408
    Abstract: Compositions and methods for prevention and treatment of uncontrolled formation of intravascular fibrin clots, which are capable of selective dissolution of pathological nascent clots formed intravascularly, with minimal risk of unwanted dissolution of pre-existing hemostatic clots, are provided wherein fibrinolytic or anticoagulant drugs are biocompatibly coupled to red blood cell carriers.
    Type: Application
    Filed: July 1, 2003
    Publication date: March 18, 2004
    Inventors: Vladimir R. Muzykantov, Juan Carlos Murciano, Douglas Cines
  • Compositions and methods for prevention and treatment of uncontrolled formation of intravascular fibrin clots
    Publication number: 20030152563
    Abstract: Compositions and methods for prevention and treatment of uncontrolled formation of intravascular fibrin clots are provided wherein fibrinolytic or anticoagulant drugs are biocompatibly coupled to red blood cell carriers.
    Type: Application
    Filed: September 23, 2002
    Publication date: August 14, 2003
    Inventors: Vladimir R. Muzykantov, Abd Al-Roof Higazi, Juan Carlos Murciano, Douglas Cines, Ronald P. Taylor
  • Compositions and methods for prevention and treatment of uncontrolled formation of intravascular fibrin clots
    Patent number: 6488927
    Abstract: Compositions and methods for prevention and treatment of uncontrolled formation of intravascular fibrin clots are provided wherein fibrinolytic or anticoagulant drugs are biocompatibly coupled to red blood cell carriers.
    Type: Grant
    Filed: December 3, 1999
    Date of Patent: December 3, 2002
    Assignee: Trustees of the University of Pennsylvania
    Inventors: Vladimir R. Muzykantov, Abd Al-Roof Higazi, Juan Carlos Murciano, Douglas Cines
  • COMPOSITIONS AND METHODS FOR PREVENTION AND TREATMENT OF UNCONTROLLED FORMATION OF INTRAVASCULAR FIBRIN CLOTS
    Publication number: 20020099000
    Abstract: Compositions and methods for prevention and treatment of uncontrolled formation of intravascular fibrin clots are provided wherein fibrinolytic or anticoagulant drugs are biocompatibly coupled to red blood cell carriers.
    Type: Application
    Filed: December 3, 1999
    Publication date: July 25, 2002
    Inventors: VLADIMIR R. MUZYKANTOV, ABD AL-ROOF HIGAZI, JUAN CARLOS MURCIANO, DOUGLAS CINES