Patents by Inventor Juan-Cheng YANG

Juan-Cheng YANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use Of ADAM9 Inhibitor As Immunomodulator
    Publication number: 20220202783
    Abstract: The present disclosure relates to a use of an ADAM9 inhibitor in manufacture of an immunomodulator. The immunomodulator can change the distribution of immune cells in a tumor and increase the infiltration of the immune cells, thereby increasing the efficacy of cancer immunotherapy. Furthermore, the immunomodulator can be used to enhance an effectiveness of a cancer immunotherapy, and the ADAM9 inhibitor can be a compound of Formula (I), or a pharmaceutically acceptable salt or stereoisomer thereof.
    Type: Application
    Filed: April 24, 2020
    Publication date: June 30, 2022
    Applicant: China Medical University
    Inventors: Yuh-Pyng Sher, Juan-Cheng Yang, Jing-Pei Liu, Yu-Kai Huang
  • Composition including ADAM9 inhibitor and the use thereof
    Patent number: 11357759
    Abstract: The present disclosure relates to an ADAM9 inhibitor compound of formula (I), including salts, hydrates and stereoisomers thereof, compositions thereof, and methods of use therefor, including treating a person in need thereof with an effective amount of the compound or composition, and detecting a resultant improvement in the person's health or condition.
    Type: Grant
    Filed: October 29, 2018
    Date of Patent: June 14, 2022
    Assignee: CHINA MEDICAL UNIVERSITY
    Inventors: Yuh-Pyng Sher, Yang-Chang Wu, Juan-Cheng Yang, Ting-Ting Kuo, Chia-Chien Lo
  • Composition Including ADAM9 Inhibitor And The Use Thereof
    Publication number: 20210052562
    Abstract: The present disclosure relates to an ADAM9 inhibitor compound of formula (I), including salts, hydrates and stereoisomers thereof, compositions thereof, and methods of use therefor, including treating a person in need thereof with an effective amount of the compound or composition, and detecting a resultant improvement in the person's health or condition.
    Type: Application
    Filed: October 29, 2018
    Publication date: February 25, 2021
    Applicant: China Medical University
    Inventors: Yuh-Pyng Sher, Yang-Chang Wu, Juan-Cheng Yang, Ting-Ting Kuo, Chia-Chien Lo
  • Use of compound for inhibiting glutathione s-transferase omega 1 activity and method for synthesizing the same
    Patent number: 8969406
    Abstract: A compound for inhibiting activity of glutathione s-transferase omega 1 is provided and is represented by the following Formula 1: in which A is p-quino, and R is selected from the group consisting of the following Formula 1a and Formula 1b, where n in Formula 1 is 1 or 2, m in Formula 1b is 1 or 2, and n? in Formula 1b is 1, 2, or 3:
    Type: Grant
    Filed: March 18, 2013
    Date of Patent: March 3, 2015
    Assignee: China Medical University
    Inventors: Yang-Chang Wu, Kuo-Hsiung Lee, Fang-Rong Chang, Da-Wei Chuang, Juan-Cheng Yang
  • COMPOUND FOR INHIBITING GLUTATHIONE S-TRANSFERASE OMEGA 1 ACTIVITY, PHARMACEUTICAL COMPOSITION CONTAINING THEREOF, AND METHOD FOR SYNTHESIZING THE SAME
    Publication number: 20140221470
    Abstract: A compound for inhibiting activity of glutathione s-transferase omega 1 is provided and is represented by the following Formula 1: in which A is p-quino, and R is selected from the group consisting of the following Formula 1a and Formula 1b, where n in Formula 1 is 1 or 2, m in Formula 1b is 1 or 2, and n? in Formula 1b is 1, 2, or 3:
    Type: Application
    Filed: March 18, 2013
    Publication date: August 7, 2014
    Applicant: CHINA MEDICAL UNIVERSITY
    Inventors: Yang-Chang WU, Kuo-Hsiung LEE, Fang-Rong CHANG, Da-Wei CHUANG, Juan-Cheng YANG