Patents by Inventor Juan Gonzalez
Juan Gonzalez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240141060Abstract: The invention generally relates to dosage regimes of anti-Cluster of Differentiation 73 (CD73) antibodies and/or anti-ectoenzyme ectonucleoside triphosphate diphosphohydrolase 2 (ENTPD2) antibodies, used in methods of treatment of cancer in a subject, as well as dosage regimes of anti-CD73 antibodies for use in treating cancer. The invention further generally relates to dosage regimes of combinations of agents, such as combinations comprising anti-CD73 antibodies and/or anti-ENTPD2 antibodies and at least one or more of a PD-1 inhibitor, and an adenosine A2AR antagonist.Type: ApplicationFiled: January 27, 2022Publication date: May 2, 2024Inventors: Juan Gonzalez-Maffe, Randi Ellen Isaacs, Jaeyeon Kim, Lisa Nardi, Javier Alberto Otero, Nehal Parikh, Michael John Roy, Kulandayan Kasi Subramanian, Tingting Zhai
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Publication number: 20240139105Abstract: Pharmaceutical composition comprising growth-hormone releasing peptide 6 (GHRP-6), tartrate buffer at pH 5.0-6.0, and trehalose as stabilizing agent, as well as the use of said composition for the manufacture of a medicament. The invention also provides a kit of parts comprising said pharmaceutical composition and a method of treatment of an individual in need thereof, which entails the administration of a therapeutically effective amount of the pharmaceutical composition comprising of GHRP-6, tartrate buffer at pH 5.0-6.0 and trehalose.Type: ApplicationFiled: January 27, 2022Publication date: May 2, 2024Inventors: Jesús Hector SANTANA MILIAN, Francisco HERNANDEZ BERNAL, Sonia GONZALEZ BLANCO, Yasser ZARATE RIVERA, Mercedes Dania BACARDÍ FERNÁNDEZ, Diana GARCIA DEL BARCO HERRERA, Yaima GONZÁLEZ GONZÁLEZ, Raúl Fidel CASTRO ODIO, Jorge Amador BERLANGA ACOSTA, Gerardo Enrique GUILLEN NIETO, Juan VALIENTE MUSTELIER
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Patent number: 11952170Abstract: The present invention relates to a container with an inner decorative figure and its manufacturing method. The container has a container body having a top cover. The top cover has an outlet neck projecting from the central portion to engage a cap; and, a geometric or amorphous through-peripheral wall in the lower part of the container body. The through-peripheral wall has an external peripheral wall and an internal peripheral wall. The external peripheral wall has as a threaded section. A figure includes an upper section with the desired figure and a lower section. The lower section has a stop section to delimit the entrance of the figure towards the inside of the container; and, a lower cap that is coupled to the lower part of the container body to retain and maintain fixed the position of the lower section of the decorative figure.Type: GrantFiled: April 10, 2019Date of Patent: April 9, 2024Assignee: Vitro, S.A.B. de C.V.Inventors: Humberto González Popoca, Miguel Ángel Proa Pérez, Braulio Rosas Fernández, Gustavo Bobadilla Cortés, Guillermo Perales Aldaco, Juan Picazo Ortega, Miguel Ángel Ortiz Caravantes
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Patent number: 11937625Abstract: The invention relates to a nutraceutical formulation of blueberry extract, fish oil (omega-3 and omega-6), recombinant human lactoferrin, vitamin A and vitamin E, for human oral consumption. The invention belongs to the field of ophthalmology and has been developed as a coadjuvant for preserving the health of the precorneal film and of the eye surface. This formulation contains an extract of natural origin (Vaccinium myrtillus L) with antioxidant and anti-inflammatory properties; it also uses eicosapentaenoic acid (EPA), omega-6, and docosahexaenoic acid (DHA), omega-3, obtained from fish oil and which, together with lactoferrin, vitamin A and vitamin E, improves tear quality, since these compounds have anti-microbial and anti-inflammatory effects. This formulation has been designed as a coadjuvant for preserving the health of the precorneal film.Type: GrantFiled: December 18, 2018Date of Patent: March 26, 2024Inventors: Arturo Santos Garcia, Juan Carlos Altamirano Vallejo, Jose Alonso Chavez Garcia, Alejandro Gonzalez De La Rosa
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Publication number: 20240083320Abstract: A table assembly for a vehicle includes a first mounting bracket attachable on a first fixed vehicle component and a table body. The table body has a plurality of rigid segments joined together by a corresponding plurality of flexible joints. A first one of the flexible joints extends in a first direction and at least another of the flexible joints extends in a second direction perpendicular to the first direction. The table body is configured to be removably coupled with the first mounting bracket such that the first mounting bracket supports the table body in a generally horizontal position with the table body in a first configuration folded along the first flexible joint such that the at least another of the flexible joints is positioned to extend along one of the plurality of rigid segments.Type: ApplicationFiled: September 9, 2022Publication date: March 14, 2024Applicant: Ford Global Technologies, LLCInventors: Oscar Martinez, Juan Carlos Aquino Bustamante, Misael Gonzalez, Raul Ezequiel Alvarez Ruiz, Jorge Flores Corona
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Patent number: 11919967Abstract: An antibody or fragment thereof, against presenilin, and more specifically against the luminal loop 1 of presenilin, for use in the treatment of cancer, by way of administrating a therapeutically effective quantity of the antibody or a fragment thereof, or a pharmaceutical composition comprising thereof, to a subject who suffers from cancer.Type: GrantFiled: August 3, 2018Date of Patent: March 5, 2024Assignees: ALZHEIMUR 2012 S.L., FUNDACION UNIVERSITARIA SAN ANTONIO, IBSAL (INSTITUTO DE INVESTIGACION BIOMEDICA DE SALAMANC, UNIVERSIDAD DE SALAMANCAInventors: Rogelio Gonzalez Sarmiento, Miguel Rodriguez Manotas, Javier Fernandez Mateos, Juan Carlos Gallar Ruiz, David Florenciano Gomez
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Patent number: 11882855Abstract: A reduced calorie nutrient enriched food product is produced by converting sucrose to monosaccharides and by selectively separating high molecular weight nutrients and sucrose in a food product such as a juice. The sucrose may be converted to non-digestible oligosaccharides. The process may also include separating a feed juice into a solids-rich fraction and a clarified juice fraction; treating the clarified juice fraction to form a high molecular weight-rich and oligosaccharide-rich fraction that can be combined with the solids-rich fraction to form a reduced calorie nutrient enriched liquid.Type: GrantFiled: July 5, 2022Date of Patent: January 30, 2024Assignee: Tropicana Products, Inc.Inventors: Johnny Casasnovas, Yongsoo Chung, Juan Gonzalez, Steven Havlik, Jeffrey D. Mathews, Taehyung Yi
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Publication number: 20220330582Abstract: A reduced calorie nutrient enriched food product is produced by converting sucrose to monosaccharides and by selectively separating high molecular weight nutrients and sucrose in a food product such as a juice. The sucrose may be converted to non-digestible oligosaccharides. The process may also include separating a feed juice into a solids-rich fraction and a clarified juice fraction; treating the clarified juice fraction to form a high molecular weight-rich and oligosaccharide-rich fraction that can be combined with the solids-rich fraction to form a reduced calorie nutrient enriched liquid.Type: ApplicationFiled: July 5, 2022Publication date: October 20, 2022Inventors: Johnny Casasnovas, Yongsoo Chung, Juan Gonzalez, Steven Havlik, Jeffrey D. Mathews, Taehyung Yi
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Patent number: 11412764Abstract: A reduced calorie nutrient enriched food product is produced by converting sucrose to monosaccharides and by selectively separating high molecular weight nutrients and sucrose in a food product such as a juice. The sucrose may be converted to non-digestible oligosaccharides. The process may also include separating a feed juice into a solids-rich fraction and a clarified juice fraction; treating the clarified juice fraction to form a high molecular weight-rich and oligosaccharide-rich fraction that can be combined with the solids-rich fraction to form a reduced calorie nutrient enriched liquid.Type: GrantFiled: August 29, 2019Date of Patent: August 16, 2022Assignee: Tropicana Products, Inc.Inventors: Johnny Casasnovas, Yongsoo Chung, Juan Gonzalez, Steven Havlik, Jeffrey D. Mathews, Taehyung Yi
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Publication number: 20220220772Abstract: Lock device (1) which incorporates a closure assembly (2) that can move between an open position and a closed position, a locking device to lock said closure assembly (2) in the closed position, a first actuator (3, 31) and a second actuator (4, 41), both the first actuator (3, 31) and the second actuator (4, 41) having a locked position, in which a locking or retention action is applied, and an unlocked position, both the first and the second actuators having respective control devices which allow orders to be given to change the position of each respective actuator, wherein the first actuator and the second actuator are arranged in such a way that unlocking the locking device requires that both control devices place their respective actuator in the unlocked position.Type: ApplicationFiled: March 29, 2022Publication date: July 14, 2022Inventors: PABLO IBAÑEZ ROIG, JUAN GONZALEZ SISTERNAS
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Patent number: 11339586Abstract: Lock device (1) which incorporates a closure assembly (2) that can move between an open position and a closed position, a locking device to lock said closure assembly (2) in the closed position, a first actuator (3, 31) and a second actuator (4, 41), both the first actuator (3, 31) and the second actuator (4, 41) having a locked position, in which a locking or retention action is applied, and an unlocked position, both the first and the second actuators having respective control devices which allow orders to be given to change the position of each respective actuator, wherein the first actuator and the second actuator are arranged in such a way that unlocking the locking device requires that both control devices place their respective actuator in the unlocked position.Type: GrantFiled: August 12, 2019Date of Patent: May 24, 2022Assignee: MONTAJES ELECTRONICOS DORCAS, S.LInventors: Pablo Ibañez Roig, Juan Gonzalez Sisternas
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Publication number: 20210189822Abstract: A wellhead assembly with an external test port for testing a primary seal at an interface of a wellhead and a base. The assembly includes unique architecture with a secondary seal provided adjacent the primary. In this manner, testing of the primary seal from an external location may proceed without concern over a false indication of primary seal failure. That is, for circumstances where a more interior side of the seal fails under pressure testing even though an outer face of the seal might remain in sealing engagement, the secondary seal would ensure that the outer sealing engagement is detected. As a result, a practical manner of testing the wellhead seal from an external location without the need of plugging the wellbore is provided.Type: ApplicationFiled: December 15, 2020Publication date: June 24, 2021Inventors: Edward Ganzinotti, III, Craig Cotton, Pheng Aun Soh, Juan Gonzalez
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Publication number: 20210059279Abstract: A reduced calorie nutrient enriched food product is produced by converting sucrose to monosaccharides and by selectively separating high molecular weight nutrients and sucrose in a food product such as a juice. The sucrose may be converted to non-digestible oligosaccharides. The process may also include separating a feed juice into a solids-rich fraction and a clarified juice fraction; treating the clarified juice fraction to form a high molecular weight-rich and oligosaccharide-rich fraction that can be combined with the solids-rich fraction to form a reduced calorie nutrient enriched liquid.Type: ApplicationFiled: August 29, 2019Publication date: March 4, 2021Inventors: Johnny Casasnovas, Yongsoo Chung, Juan Gonzalez, Steven Havlik, Jeffrey D. Mathews, Taehyung Yi
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Patent number: 10719903Abstract: Methods for dynamically executing computer code across multiple disparate processing unit architectures are disclosed. During execution of a first portion of computer code on a first processing unit, it is determined that a first dynamic hardware behavior of a plurality of dynamic hardware behaviors will occur at a subsequent point in time, based on a second dynamic hardware behavior that is occurring. The methods include determining to execute code corresponding to the first dynamic hardware behavior on a second processing unit, rather than the first processing unit, and scheduling computer program code corresponding to the first dynamic hardware behavior to execute on the second processing unit rather than the first processing unit. Upon completion of execution of the computer code corresponding to the first dynamic hardware behavior, a remaining portion of the computer code is scheduled to execute on the first processing unit.Type: GrantFiled: December 22, 2017Date of Patent: July 21, 2020Assignee: International Business Machines CorporationInventors: Fausto Artico, Jose R. Brunheroto, Juan Gonzalez Garcia, Nelson Mimura Gonzalez
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Publication number: 20200048930Abstract: Lock device (1) which incorporates a closure assembly (2) that can move between an open position and a closed position, a locking device to lock said closure assembly (2) in the closed position, a first actuator (3, 31) and a second actuator (4, 41), both the first actuator (3, 31) and the second actuator (4, 41) having a locked position, in which a locking or retention action is applied, and an unlocked position, both the first and the second actuators having respective control devices which allow orders to be given to change the position of each respective actuator, wherein the first actuator and the second actuator are arranged in such a way that unlocking the locking device requires that both control devices place their respective actuator in the unlocked position.Type: ApplicationFiled: August 12, 2019Publication date: February 13, 2020Inventors: PABLO IBAÑEZ ROIG, JUAN GONZALEZ SISTERNAS
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Patent number: 10540737Abstract: Methods for estimating accelerator performance for dynamic hardware behaviors are disclosed. Computer program code to be executed on a first processing unit is received, and an execution of the computer code on the first processing unit is monitored to determine a plurality of performance characteristics. A plurality of dynamic hardware behaviors is determined by applying a clustering algorithm to the performance characteristics, and an equivalent accelerator portion of computer code to be executed on a second processing unit is generated by translating a set of instructions in a first portion of computer code corresponding to a first one of the plurality of dynamic hardware behaviors to an equivalent set of instructions to be executed on the second processing unit. An estimated measure of performance for executing the equivalent accelerator portion on the second processing unit is determined for the first one of the plurality of dynamic hardware behaviors.Type: GrantFiled: December 22, 2017Date of Patent: January 21, 2020Assignee: International Business Machines CorporationInventors: Fausto Artico, Jose R. Brunheroto, Juan Gonzalez Garcia, Nelson Mimura Gonzalez
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Publication number: 20190388480Abstract: A pre-conditioned probiotic composition and method of forming the pre-conditioned probiotic composition comprises introducing thawed probiotic cells into a pre-conditioning environment having sufficient nutrients and conditions to prepare the thawed probiotic cells for surviving and successfully thriving in a targeted food product. Thawed probiotic cells are then provided with an incubation period of at least 2 hours to produce inoculation pre-treated probiotic cells with improved shelf life in a food product.Type: ApplicationFiled: June 22, 2018Publication date: December 26, 2019Inventors: Zeinab ALI, Varadharajan Radhamani BASKER, Yumin CHEN, Cordula FRANKRONE, Juan GONZALEZ, Prabhakar KASTURI, Yih Jennifer LEE, Tracy MUI, Elizabeth Gutierrez PRICE, James D. SCHUMAN, Kelly VAN DYKE
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Patent number: 10370157Abstract: The invention relates to a self-extracting stopper which can be accommodated inside the neck of the bottle, and which does not require a corkscrew or any other tool for the extraction thereof, formed by an assembly of parts preferably made of a plastic material and which, once assembled, permit a bottle or container to be stoppered. The face of the drum (8) and the surface of revolution of the flexible cylinder (4) can also carry marks that are engraved or in shallow relief. In this way, the assembly of the self-extracting stopper is formed by six elements and a cork cover (1), a nut (2), a flexible cylinder (5), a drum (8), a screw (12) and a wing nut (15), all of which are disposed and assembled according to their axial geometry, and which permit a method and process to be provided whereby bottles and/or containers can be stoppered or opened manually or automatically, and said self-extracting stopper being reusable.Type: GrantFiled: August 6, 2015Date of Patent: August 6, 2019Assignee: TAPOINTEL S.L.Inventors: Juan Gonzalez Valencia, Jose Andres Vidal Martinez, Jose Gomez Vietes, Jesus Vidal Iglesias, Julio David Vidal Iglesias
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Publication number: 20190197652Abstract: Methods for dynamically executing computer code across multiple disparate processing unit architectures are disclosed. During execution of a first portion of computer code on a first processing unit, it is determined that a first dynamic hardware behavior of a plurality of dynamic hardware behaviors will occur at a subsequent point in time, based on a second dynamic hardware behavior that is occurring. The methods include determining to execute code corresponding to the first dynamic hardware behavior on a second processing unit, rather than the first processing unit, and scheduling computer program code corresponding to the first dynamic hardware behavior to execute on the second processing unit rather than the first processing unit. Upon completion of execution of the computer code corresponding to the first dynamic hardware behavior, a remaining portion of the computer code is scheduled to execute on the first processing unit.Type: ApplicationFiled: December 22, 2017Publication date: June 27, 2019Inventors: Fausto ARTICO, Jose R. BRUNHEROTO, Juan Gonzalez GARCIA, Nelson Mimura GONZALEZ
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Publication number: 20190197653Abstract: Methods for estimating accelerator performance for dynamic hardware behaviors are disclosed. Computer program code to be executed on a first processing unit is received, and an execution of the computer code on the first processing unit is monitored to determine a plurality of performance characteristics. A plurality of dynamic hardware behaviors is determined by applying a clustering algorithm to the performance characteristics, and an equivalent accelerator portion of computer code to be executed on a second processing unit is generated by translating a set of instructions in a first portion of computer code corresponding to a first one of the plurality of dynamic hardware behaviors to an equivalent set of instructions to be executed on the second processing unit. An estimated measure of performance for executing the equivalent accelerator portion on the second processing unit is determined for the first one of the plurality of dynamic hardware behaviors.Type: ApplicationFiled: December 22, 2017Publication date: June 27, 2019Inventors: Fausto ARTICO, Jose R. Brunheroto, Juan Gonzalez Garcia, Nelson Mimura Gonzalez