Patents by Inventor Judes Poirier

Judes Poirier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THIENOPYRIMIDINE INHIBITORS OF FARNESYL AND/OR GERANYLGERANYL PYROPHOSPHATE SYNTHASE
    Publication number: 20150307532
    Abstract: The present invention relates to novel compounds, compositions containing same and methods for inhibiting human farnesyl pyrophosphate synthase or for the treatment or prevention of disease conditions using said compounds;
    Type: Application
    Filed: November 19, 2013
    Publication date: October 29, 2015
    Applicant: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
    Inventors: Youla S. TSANTRIZOS, Judes POIRIER, Michael SEBAG, Albert BERGHUIS, Jaeok PARK, Joris WIM DE SCHUTTER
  • Apolipoprotein E polymorphism and treatment of alzheimer's disease
    Patent number: 7049078
    Abstract: Disclosed herein are methods for identifying a patient for the treatment of cognitive impairments.
    Type: Grant
    Filed: June 29, 1999
    Date of Patent: May 23, 2006
    Inventor: Judes Poirier
  • Pharmacogenetic methods for use in the treatment of nervous system diseases
    Patent number: 7001736
    Abstract: The present invention provides a method for the determining the appropriate therapy and/or prognosis for a patient diagnosed with a non-Alzheimer's disease (AD) neurological disease based upon the patient's apoE allele load. The invention also provides a method for the identification of human subjects with a non-AD neurological disease that are likely to respond in clinical trials that test pharmaceuticals useful in the treatment of neurological diseases.
    Type: Grant
    Filed: February 8, 2000
    Date of Patent: February 21, 2006
    Inventor: Judes Poirier
  • 3-Hydroxymethylglutaryl coenzyme a reductase and diagnosis and prognostication of dementia
    Publication number: 20050069881
    Abstract: The invention relates to methods and commercial packages for the diagnosis and/or prognostication of a dementia. The methods are based upon the assessment of a feature or features relating to 3-hydroxymethylglutaryl coenzyme A reductase (HMGR) gene, a polymorphism associated with the gene, the nature of mRNA transcripts produced, and/or HMGR protein activity. Applicants have determined that a decrease in HMGR activity correlates with Alzheimer disease. Applicants have further determined that the presence of a polymorphism in the HMGR gene correlates with Alzheimer disease. Applicants have identified two abnormal HMGR mRNA transcripts and have shown that their presence correlates with Alzheimer disease.
    Type: Application
    Filed: August 29, 2002
    Publication date: March 31, 2005
    Inventors: Judes Poirier, Louise Theroux-Lamarre, Doris Dea, Nicole Aumont
  • Methods for increasing ApoE levels for the treatment of neurodegenerative disease
    Publication number: 20010051602
    Abstract: Disclosed herein is a method for reducing neurodegenerative disease in patients by administration of a therapeutically-effective amount of a compound which can increase ApoE levels.
    Type: Application
    Filed: June 22, 2001
    Publication date: December 13, 2001
    Inventor: Judes Poirier
  • Methods for increasing ApoE levels for the treatment of neurodegenerative disease
    Patent number: 6274603
    Abstract: Disclosed herein is a method for reducing neurodegenerative disease in patients by administration of a therapeutically-effective amount of a compound which can increase ApoE levels.
    Type: Grant
    Filed: September 24, 1998
    Date of Patent: August 14, 2001
    Assignee: McGill University
    Inventor: Judes Poirier
  • APOLIPOPROTEIN E POLYMORPHISM AND TREATMENT OF ALZHEIMER'S DISEASE
    Publication number: 20010006784
    Abstract: Disclosed herein are methods for identifying a patient for the treatment of cognitive impairments.
    Type: Application
    Filed: June 29, 1999
    Publication date: July 5, 2001
    Inventor: JUDES POIRIER
  • Methods for assessing the prognosis of a patient with a neurodegenerative disease
    Patent number: 6022683
    Abstract: The present invention provides a method for the determining the appropriate therapy and/or prognosis for a patient diagnosed with a non-Alzheimer's disease (AD) neurological disease based upon the patient's apoE allele load. The invention also provides a method for the identification of human subjects with a non-AD neurological disease that are likely to respond in clinical trials that test pharmaceuticals useful in the treatment of neurological diseases.
    Type: Grant
    Filed: December 16, 1996
    Date of Patent: February 8, 2000
    Assignee: Nova Molecular Inc.
    Inventor: Judes Poirier
  • Apolipoprotein E polymorphism and treatment of Alzheimer's disease
    Patent number: 5935781
    Abstract: The present invention relates to a method for the identification of human subjects to be responsive to cholinomimetic therapy comprising determining the absence of apolipoprotein E4 (apoE4) alleles in a biological sample of the patient where the absence of at least one apoE4 allele indicates a predisposition to respond to cholinomimetic therapy and methods of administering cholinomimetics to such identified subjects.
    Type: Grant
    Filed: February 21, 1997
    Date of Patent: August 10, 1999
    Assignee: McGill University
    Inventor: Judes Poirier