Patents by Inventor Judith L. Treadway

Judith L. Treadway has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating diabetic cardiomyopathy using glycogen phosphorylase inhibitors
    Patent number: 6867184
    Abstract: The present invention provides methods of treating diabetic cardiomyopathy, the methods comprising administering to a patient having or at risk of having diabetic cardiomyopathy a therapeutically effective amount of a glycogen phosphorylase inhibitor.
    Type: Grant
    Filed: January 23, 2001
    Date of Patent: March 15, 2005
    Assignee: Pfizer, Inc.
    Inventor: Judith L. Treadway
  • Substituted N-(indole-2-carbonyl) -amides and derivatives as glycogen phosphorylase inhibitors
    Patent number: 6846820
    Abstract: This invention relates to certain indole-2-carboxamides of formula (I) and the pharmaceutically acceptable salts and prodrugs thereof, wherein R6 is carboxy, (C1-C8)alkoxycarbonyl, C(O)NR8R9 or C(O)R12, useful as inhibitors of glycogen phosphorylase, methods of treating glycogen phosphorylase dependent diseases or conditions with such compounds and pharmaceutical compositions comprising such compounds.
    Type: Grant
    Filed: June 17, 2003
    Date of Patent: January 25, 2005
    Assignee: Pfizer Inc.
    Inventors: Dennis J. Hoover, Bernard Hulin, William H. Martin, Judith L. Treadway
  • Methods of treating infection using anitbiotics and glycogen phosphorylase inhibitors
    Publication number: 20040082614
    Abstract: The invention provides methods of treating infection, such as Chlamydia pneumoniae infection, in a mammal comprising administering to a mammal effective amounts of azithromycin and a glycogen phosphorylase inhibitor. The invention also provides methods of treating atherosclerosis by administration of effective amounts of azithromycin and a glycogen phosphorylase inhibitor. Pharmaceutical compositions and kits are also provided.
    Type: Application
    Filed: July 16, 2003
    Publication date: April 29, 2004
    Applicant: Pfizer Inc.
    Inventors: Judith L. Treadway, Joyce Anne Sutcliffe
  • Substituted N-(indole-2-carbonyl) -amides and derivatives as glycogen phosphorylase inhibitors
    Publication number: 20040006088
    Abstract: 1
    Type: Application
    Filed: June 17, 2003
    Publication date: January 8, 2004
    Applicant: Pfizer Inc.
    Inventors: Dennis J. Hoover, Bernard Hulin, William H. Martin, Judith L. Treadway
  • Substituted N-( indole-2-carbonyl-) amides and derivatives as glycogen phosphorylase inhibitors
    Patent number: 6649634
    Abstract: This invention relates to certain indole-2-carboxamides of formula (I) and the pharmaceutically acceptable salts and prodrugs thereof, wherein R6 is carboxy, (C1-C8)alkoxycarbonyl, C(O)NR8R9 or C(O)R12, useful as inhibitors of glycogen phosphorylase, methods of treating glycogen phosphorylase dependent diseases or conditions with such compounds and pharmaceutical compositions comprising such compounds.
    Type: Grant
    Filed: June 14, 2001
    Date of Patent: November 18, 2003
    Assignee: Pfizer, Inc.
    Inventors: Dennis J. Hoover, Bernard Hulin, William H. Martin, Judith L. Treadway
  • Treatment of diabetes and diabetic complications with NHE-1 inhibitors
    Publication number: 20030212104
    Abstract: This invention relates to methods of treating or preventing type 2 diabetes, diabetic neuropathy, diabetic cardiomyopathy, cataracts, diabetic retinopathy, foot ulcers, diabetic microangiopathy, diabetic macroangiopathy, diabetic ischemia reperfusion injury, diabetic cardiac ischemia reperfusion injury and/or insulin resistance syndrome (IRS) in mammals, particularly in humans, by administering a sodium-hydrogen exchanger type 1 (NHE-1) inhibitor or a pharmaceutical composition containing such an inhibitor. This invention also relates to combinations comprising NHE-1 inhibitors and a second pharmaceutical agent, said combinations being useful in treating type 2 diabetes, IRS, diabetic neuropathy, diabetic cardiomyopathy, cataracts, diabetic retinopathy, foot ulcers, diabetic ischemia reperfusion injury, diabetic cardiac ischemia reperfusion injury, diabetic microangiopathy and/or diabetic macroangiopathy.
    Type: Application
    Filed: May 1, 2003
    Publication date: November 13, 2003
    Applicant: Pfizer Inc.
    Inventors: W. Ross Tracey, Judith L. Treadway
  • Use of glycogen phosphorylase inhibitors
    Publication number: 20030004162
    Abstract: The invention provides methods of treating prophylactically an individual in whom Type 2 diabetes mellitus has not yet presented, but in whom there is an increased risk of developing such condition, which methods comprise administering to an individual in need thereof an effective amount of a glycogen phosphorylase inhibitor; effective amounts of a glycogen phosphorylase inhibitor and a non-glycogen phosphorylase inhibiting anti-diabetic agent; or effective amounts of a glycogen phosphorylase inhibitor and an anti-obesity agent.
    Type: Application
    Filed: March 20, 2001
    Publication date: January 2, 2003
    Inventor: Judith L. Treadway
  • Substituted N-( indole-2-carbonyl-) amides and derivatives as glycogen phosphorylase inhibitors
    Publication number: 20020028810
    Abstract: This invention relates to certain indole-2-carboxamides of formula (I) and the pharmaceutically acceptable salts and prodrugs thereof, wherein R6 is carboxy, (C1-C8)alkoxycarbonyl, C(O)NR8R9 or C(O)R12, useful as inhibitors of glycogen phosphorylase, methods of treating glycogen phosphorylase dependent diseases or conditions with such compounds and pharmaceutical compositions comprising such compounds.
    Type: Application
    Filed: June 14, 2001
    Publication date: March 7, 2002
    Inventors: Dennis J. Hoover, Bernard Hulin, William H. Martin, Judith L. Treadway
  • Methods of treating diabetic cardiomyopathy using glycogen phosphorylase inhibitors
    Publication number: 20010046958
    Abstract: The present invention provides methods of treating diabetic cardiomyopathy, the methods comprising administering to a patient having or at risk of having diabetic cardiomyopathy a therapeutically effective amount of a glycogen phosphorylase inhibitor.
    Type: Application
    Filed: January 23, 2001
    Publication date: November 29, 2001
    Inventor: Judith L. Treadway
  • Substituted n-(indole-2-carbonyl-) amides and derivatives as glycogen phosphorylase inhibitors
    Patent number: 6297269
    Abstract: Compounds of the formula I: and their compositions are useful as glycogen phosphorylase inhibitors.
    Type: Grant
    Filed: December 2, 1997
    Date of Patent: October 2, 2001
    Assignee: Pfizer Inc.
    Inventors: Bernard Hulin, Dennis J. Hoover, Judith L. Treadway, William H. Martin
  • Substituted n-(indole-2-carbonyl)glycinamides and derivates as glycogen phosphorylase inhibitors
    Patent number: 6277877
    Abstract: Compounds of Formula (I) wherein R6 is carboxy, (C1-C8)alkoxycarbonyl, benzyloxycarbonyl, C(O)NR8R9 or C(O)R12 as glycogen phosphorylase inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat diabetes, hyperglycemia, hypercholesterolemia, hypertension, hyperisulinemia, hyperlipidemia, atherosclerosis and myocardial ischemia in mammals.
    Type: Grant
    Filed: August 15, 2000
    Date of Patent: August 21, 2001
    Assignee: Pfizer, Inc.
    Inventors: Dennis J. Hoover, Bernard Hulin, William H. Martin, Douglas Phillips, Judith L. Treadway
  • Substituted n-(indole-2-carbonyl)-glycinamides and derivatives as glycogen phosphorylase inhibitors
    Patent number: 6107329
    Abstract: Compounds of Formula (1) wherein R.sub.6 is carboxy, (C.sub.1 -C.sub.8)alkoxycarbonyl, benzyloxycarbonyl, C(O)NR.sub.8 R.sub.9 or C(O)R.sub.12 as glucogen phosphorylase inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat diabetes, hyperglycemia, hypercholesterolemia, hypertension, hyperinsulinemia, hyperlipidemia, atherosclerosis and myocardial ischemia in mammals.
    Type: Grant
    Filed: December 2, 1997
    Date of Patent: August 22, 2000
    Assignee: Pfizer, Inc.
    Inventors: Dennis J. Hoover, Bernard Hulin, William H. Martin, Douglas Phillips, Judith L. Treadway
  • Method of reducing tissue damage associated with non-cardiac ischemia using glycogen phosphorylase inhibitors
    Patent number: 5952322
    Abstract: A method of preventing non-cardiac tissue damage resulting from ischemia and/or hypoxia, comprising administering to a patient in need of such treatment an effective amount of an glycogen phosphorylase inhibitor.
    Type: Grant
    Filed: November 25, 1997
    Date of Patent: September 14, 1999
    Assignee: Pfizer Inc.
    Inventors: Dennis J. Hoover, William H. Martin, Judith L. Treadway, W. Ross Tracey