Abstract: Methods and apparatus for correcting the gaze direction and the origin (entrance pupil) in gaze tracking systems. During enrollment after an eye model is obtained, the pose of the eye when looking at a target prompt is determined. This information is used to estimate the true visual axis of the eye. The visual axis may then be used to correct the point of view (PoV) with respect to the display during use. If a clip-on lens is present, a corrected gaze axis may be calculated based on the known optical characteristics and pose of the clip-on lens. A clip-on corrected entrance pupil may then be estimated by firing two or more virtual rays through the clip-on lens to determine the intersection between the rays and the corrected gaze axis.

Abstract: Disclosed are a method of treating cancer and/or other proliferative diseases comprising orally administering N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)-1-piperazinyl)-2-methyl-4-pyrimidinyl)amino)-1,3 -thiazole-5-carboxamide or a salt thereof, and pharmaceutical compositions comprising N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)-1-piperazinyl)-2-methyl-4 -pyrimidinyl)amino)-1,3-thiazole-5-carboxamide or a salt thereof. Also disclosed are N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)-1-piperazinyl)-2-methyl-4-pyrimidinyl)amino)-1,3-thiazole-5-carboxamide salts, as well as crystalline forms thereof.

Abstract: The invention relates to pharmaceutical compositions of ?N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide, and to methods of using the pharmaceutical compositions in the treatment of oncological and immunological disorders

Abstract: The present invention provides an efavirenz tablet formulation which, when administered as a single dose to a subject, provides a mean maximum plasma concentration (Cmax) of about 4 ?M to about 14 ?M, a mean time of maximum plasma concentration (Tmax) of about 2 hours to about 5 hours, and a mean area under the plasma concentration versus time curve from time zero to time infinity (AUC) of about 190 ?Mhour to about 470 ?Mhour.