Patents by Inventor Juliana Blum

Juliana Blum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TISSUE-ENGINEERED CONSTRUCTS
    Publication number: 20210246419
    Abstract: The present invention provides constructs including a tubular biodegradable polyglycolic acid scaffold, wherein the scaffold may be coated with extracellular matrix proteins and substantially acellular. The constructs can be utilized as an arteriovenous graft, a coronary graft, a peripheral artery bypass conduit, or a urinary conduit. The present invention also provides methods of producing such constructs.
    Type: Application
    Filed: January 27, 2021
    Publication date: August 12, 2021
    Applicant: Humacyte, Inc.
    Inventors: Shannon L.M. DAHL, Laura E. NIKLASON, Justin T. STRADER, William E. TENTE, Joseph J. LUNDQUIST, Juliana Blum, Heather L. Prichard
  • Tubular tissue-engineered constructs
    Patent number: 9657265
    Abstract: The present invention provides constructs including a tubular biodegradable polyglycolic acid scaffold, wherein the scaffold may be coated with extracellular matrix proteins and substantially acellular. The constructs can be utilized as an arteriovenous graft, a coronary graft, a peripheral artery bypass conduit, or a urinary conduit. The present invention also provides methods of producing such constructs.
    Type: Grant
    Filed: September 24, 2014
    Date of Patent: May 23, 2017
    Assignee: Humacyte, Inc.
    Inventors: Shannon L. M. Dahl, Laura E. Niklason, Juliana Blum, Justin T. Strader, William E. Tente, Heather L. Prichard, Joseph J. Lundquist
  • TISSUE-ENGINEERED CONSTRUCTS
    Publication number: 20170135805
    Abstract: The present invention provides constructs including a tubular biodegradable polyglycolic acid scaffold, wherein the scaffold may be coated with extracellular matrix proteins and substantially acellular. The constructs can be utilized as an arteriovenous graft, a coronary graft, a peripheral artery bypass conduit, or a urinary conduit. The present invention also provides methods of producing such constructs.
    Type: Application
    Filed: January 31, 2017
    Publication date: May 18, 2017
    Inventors: Shannon L.M. DAHL, Laura E. NIKLASON, Juliana BLUM, Justin T. STRADER, William E. TENTE, Heather L. PRICHARD, Joseph J. LUNDQUIST
  • Tissue-engineered constructs
    Patent number: 9556414
    Abstract: The present invention provides constructs including a tubular biodegradable polyglycolic acid scaffold, wherein the scaffold may be coated with extracellular matrix proteins and substantially acellular. The constructs can be utilized as an arteriovenous graft, a coronary graft, a peripheral artery bypass conduit, or a urinary conduit. The present invention also provides methods of producing such constructs.
    Type: Grant
    Filed: January 6, 2012
    Date of Patent: January 31, 2017
    Assignee: HUMACYTE
    Inventors: Shannon L. M. Dahl, Laura E. Niklason, Juliana Blum, Justin T. Strader, William E. Tente, Heather L. Prichard, Joseph J. Lundquist
  • Tissue and organ graft bioreactor and method of operation
    Patent number: 9127242
    Abstract: A single-use, single or multiple tissue, organ, and graft bioreactor and environmental control system is designed to replicate the necessary conditions for growth of tissues, organs, or grafts, while addressing problems in scaling up the tissue growth; adaptation to a single-use or disposable format; and operation as a stand-alone unit that provides full environmental control of cell culture conditions.
    Type: Grant
    Filed: April 5, 2010
    Date of Patent: September 8, 2015
    Inventors: Patrick M. Guertin, Parrish M. Galliher, Michael Fisher, Joseph D. Crowell, Colin R. Tuohey, Laura A. Niklason, William E. Tente, Shannon M. Dahl, Juliana Blum, Justin Strader
  • TUBULAR TISSUE-ENGINEERED CONSTRUCTS
    Publication number: 20150012083
    Abstract: The present invention provides constructs including a tubular biodegradable polyglycolic acid scaffold, wherein the scaffold may be coated with extracellular matrix proteins and substantially acellular. The constructs can be utilized as an arteriovenous graft, a coronary graft, a peripheral artery bypass conduit, or a urinary conduit. The present invention also provides methods of producing such constructs.
    Type: Application
    Filed: September 24, 2014
    Publication date: January 8, 2015
    Inventors: Shannon L.M. Dahl, Laura E. Niklason, Juliana Blum, Justin T. Strader, William E. Tente, Heather L. Prichard, Joseph J. Lundquist
  • Compositions and Methods for Soft Tissue Augmentation
    Publication number: 20140356323
    Abstract: The present invention provides compositions comprising isolated human collagen, isolated human elastin and a pharmaceutically acceptable carrier wherein the human elastin is substantially insoluble in water with a molecular weight greater than 100 kDa. The present invention further provides methods and kits for soft tissue augmentation.
    Type: Application
    Filed: August 18, 2014
    Publication date: December 4, 2014
    Inventors: Laura E. Niklason, Yuling Li, Juliana Blum, Shannon L.M. Dahl, Geoffrey Erickson, Frank Zeigler
  • TISSUED-ENGINEERED CONSTRUCTS
    Publication number: 20130345824
    Abstract: The present invention provides constructs including a tubular biodegradable polyglycolic acid scaffold, wherein the scaffold may be coated with extracellular matrix proteins and substantially acellular. The constructs can be utilized as an arteriovenous graft, a coronary graft, a peripheral artery bypass conduit, or a urinary conduit. The present invention also provides methods of producing such constructs.
    Type: Application
    Filed: January 6, 2012
    Publication date: December 26, 2013
    Applicant: HUMACYTE
    Inventors: Shannon L.M. Dahl, Laura E. Niklason, Juliana Blum, Justin T. Strader, William E. Tente, Heather L. Prichard, Joseph Lundquist
  • Compositions and Methods for Soft Tissue Augmentation
    Publication number: 20120230950
    Abstract: The present invention provides compositions comprising isolated human collagen, isolated human elastin and a pharmaceutically acceptable carrier wherein the human elastin is substantially insoluble in water with a molecular weight greater than 100 kDa. The present invention further provides methods and kits for soft tissue augmentation.
    Type: Application
    Filed: May 21, 2012
    Publication date: September 13, 2012
    Applicant: Humacyte, Inc.
    Inventors: Laura Niklason, Yuling Li, Juliana Blum, Shannon Dahl, Geoffrey Erickson, Frank Zeigler
  • Compositions and methods for soft tissue augmentation
    Patent number: 8198245
    Abstract: The present invention provides compositions comprising isolated human collagen, isolated human elastin and a pharmaceutically acceptable carrier wherein the human elastin is substantially insoluble in water with a molecular weight greater than 100 kDa. The present invention further provides methods and kits for soft tissue augmentation.
    Type: Grant
    Filed: July 24, 2008
    Date of Patent: June 12, 2012
    Assignee: Humacyte, Inc.
    Inventors: Laura Niklason, Yuling Li, Juliana Blum, Shannon Dahl, Geoffrey Erickson, Frank Zeigler
  • TISSUE AND ORGAN GRAFT BIOREACTOR AND METHOD OF OPERATION
    Publication number: 20120028234
    Abstract: A single-use, single or multiple tissue, organ, and graft bioreactor and environmental control system is designed to replicate the necessary conditions for growth of tissues, organs, or grafts, while addressing problems in scaling up the tissue growth; adaptation to a single-use or disposable format; and operation as a stand-alone unit that provides full environmental control of cell culture conditions.
    Type: Application
    Filed: April 5, 2010
    Publication date: February 2, 2012
    Inventors: Patrick M. Guertin, Parrish M. Galliher, Michael Fisher, Joseph D. Crowell, Colin R. Tuohey, Laura A. Niklason, William E. Tente, Shannon M. Dahl, Juliana Blum, Justin Strader
  • ELASTIN FOR SOFT TISSUE AUGMENTATION
    Publication number: 20110020271
    Abstract: The present invention provides compositions comprising isolated elastin and a pharmaceutically acceptable carrier wherein the human elastin is substantially insoluble in water with a molecular weight greater than 100 kDa. The present invention further provides methods and kits for soft tissue augmentation.
    Type: Application
    Filed: May 20, 2010
    Publication date: January 27, 2011
    Applicant: Humacyte, Inc.
    Inventors: Laura E. Niklason, Yuling Li, Heather Prichard, Shannon Dahl, Juliana Blum
  • Compositions and methods for soft tissue augmentation
    Publication number: 20090028817
    Abstract: The present invention provides compositions comprising isolated human collagen, isolated human elastin and a pharmaceutically acceptable carrier wherein the human elastin is substantially insoluble in water with a molecular weight greater than 100 kDa. The present invention further provides methods and kits for soft tissue augmentation.
    Type: Application
    Filed: July 24, 2008
    Publication date: January 29, 2009
    Inventors: Laura Niklason, Yuling Li, Juliana Blum, Shannon Dahl, Geoffrey Erickson, Frank Zeigler