Patents by Inventor Juliana Ruiz Caro

Juliana Ruiz Caro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds and methods for the treatment of viruses and cancer
    Patent number: 9018209
    Abstract: The present invention relates to compounds according to the formula I: Where Ra is H or an optionally OH-substituted C1-C3 alkyl; R1 is OR1, an optionally substituted C4-12 carbocyclic group which may be saturated or unsaturated (including aromatic) or an optionally substituted heterocyclic group; R1 is an optionally substituted C1-C14 hydrocarbyl group or an optionally substituted heterocyclic group; R2, R3 and R4 are each independently H, an optionally substituted C1-C4 alkyl group (preferably CH3, CH2CH3 or CF3), halogen (preferably F, Cl, Br), OR, CN, NO2, a C1-C6 thioether, a C1-C6 thioester group, an optionally substituted CO2R group, an optionally substituted COR group or an optionally substituted OCOR group (preferably R4 is H); R is H or an optionally substituted C1-C6 alkyl group; RHET is an optionally substituted heterocyclic group; and pharmaceutically acceptable salts, solvates or polymorphs thereof.
    Type: Grant
    Filed: September 25, 2006
    Date of Patent: April 28, 2015
    Assignee: Yale University
    Inventors: William L. Jorgensen, Juliana Ruiz-Caro, Andrew D. Hamilton
  • Substituted benzimidazolone derivatives, medicaments comprising them and their use
    Patent number: 8791148
    Abstract: The present invention relates to novel benzimidazolone derivatives of the general formula (I) in which the substituents R1, R2, R3, A1, A2, and B are as defined in claim 1, medicaments comprising these, and the use thereof for the prophylaxis and/or treatment of vasopressin-dependent diseases.
    Type: Grant
    Filed: November 22, 2011
    Date of Patent: July 29, 2014
    Assignee: AbbVie Deutschland GmbH & Co. KG
    Inventors: Torsten Arndt, Thorsten Oost, Wilfried Lubisch, Wilfried Homberger, Liliane Unger, Juliana Ruiz Caro, Alfred Hahn
  • SUBSTITUTED BENZIMIDAZOLONE DERIVATIVES, MEDICAMENTS COMPRISING THEM AND THEIR USE
    Publication number: 20120172335
    Abstract: The present invention relates to novel benzimidazolone derivatives of the general formula (I) in which the substituents R1, R2, R3, A1, A2, and B are as defined in claim 1, medicaments comprising these, and the use thereof for the prophylaxis and/or treatment of vasopressin-dependent diseases.
    Type: Application
    Filed: November 22, 2011
    Publication date: July 5, 2012
    Inventors: Torsten Arndt, Thorsten Oost, Wilfried Lubisch, Wilfried Homberger, Liliane Unger, Juliana Ruiz Caro, Wolfgang Wernet, ALfred Hahn
  • Substituted benzimidazolone derivatives, medicaments comprising them and their use
    Patent number: 8119676
    Abstract: The present invention relates to novel benzimidazolone derivatives of the general formula (I) in which the substituents R1, R2, R3, A1, A2, and B are as defined in claim 1, medicaments comprising these, and the use thereof for the prophylaxis and/or treatment of vasopressin-dependent diseases.
    Type: Grant
    Filed: August 24, 2007
    Date of Patent: February 21, 2012
    Assignee: Abbott GmbH & Co. HG
    Inventors: Torsten Arndt, Thorsten Oost, Wilfried Lubisch, Wolfgang Wernet, Alfred Hahn, legal representative, Wilfried Hornberger, Liliane Unger, Juliana Ruiz Caro
  • Compounds and Methods for the Treatment of Viruses and Cancer
    Publication number: 20100222352
    Abstract: The present invention relates to compounds according to the formula I: Where Ra is H or an optionally OH-substituted C1-C3 alkyl; R1 is OR1, an optionally substituted C4-12 carbocyclic group which may be saturated or unsaturated (including aromatic) or an optionally substituted heterocyclic group; R1 is an optionally substituted C1-C14 hydrocarbyl group or an optionally substituted heterocyclic group; R2, R3 and R4 are each independently H, an optionally substituted C1-C4 alkyl group (preferably CH3, CH2CH3 or CF3), halogen (preferably F, Cl, Br), OR, CN, NO2, a C1-C6 thioether, a C1-C6 thioester group, an optionally substituted CO2R group, an optionally substituted COR group or an optionally substituted OCOR group (preferably R4 is H); R is H or an optionally substituted C1-C6 alkyl group; RHET is an optionally substituted heterocyclic group; and pharmaceutically acceptable salts, solvates or polymorphs thereof.
    Type: Application
    Filed: September 25, 2006
    Publication date: September 2, 2010
    Applicant: YALE UNIVERSITY
    Inventors: William L. Jorgensen, Juliana Ruiz-Caro, Andrew D. Hamilton
  • SUBSTITUTED BENZIMIDAZOLONE DERIVATIVES, MEDICAMENTS COMPRISING THEM AND THEIR USE
    Publication number: 20100152168
    Abstract: The present invention relates to novel benzimidazolone derivatives of the general formula (I) in which the substituents R1, R2, R3, A1, A2, and B are as defined in claim 1, medicaments comprising these, and the use thereof for the prophylaxis and/or treatment of vasopressin-dependent diseases.
    Type: Application
    Filed: August 24, 2007
    Publication date: June 17, 2010
    Applicant: ABBOTT GMBH & CO. KG
    Inventors: Torsten Arndt, Thorsten Oost, Wilfried Lubisch, Wolfgang Wernet, Wilfried Hornberger, Liliane Unger, Juliana Ruiz Caro