Patents by Inventor Julie M Pratt

Julie M Pratt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Artificial protein, method for absolute quantification of proteins and uses thereof
    Publication number: 20090137050
    Abstract: The invention provides an artificial protein for quantitative analysis of the proteome of a sample, cell or organism, comprising at least two consecutive peptides linked by a cleavage sequence for separating the peptides; a singular marker on one or more peptide for determination of the absolute amount of this fragment; and N-terminal and C-terminal extensions for protection of the peptides; wherein each peptide represents one single protein of the sample, cell or organism and each peptide is in a defined stoichiometry. The invention further provides a collection of peptides, a vector and a kit comprising the artificial protein and a method for quantitative analysis of the proteome.
    Type: Application
    Filed: November 18, 2005
    Publication date: May 28, 2009
    Applicant: PolyQuant GmbH
    Inventors: Julie M. Pratt, Robert Beynon, Simon Gaskell
  • Compounds
    Patent number: 7422749
    Abstract: This invention relates to newly identified Staphylococcal polynucleotides, polypeptides encoded by such polynucleotides, the uses of such polynucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides and recombinant host cells transformed with the polynucleotides. This invention also relates to inhibiting the biosynthesis or action of such polynucleotides or polypeptides and to the use of such inhibitors in therapy.
    Type: Grant
    Filed: January 25, 2007
    Date of Patent: September 9, 2008
    Assignee: Affinium Pharmaceuticals, Inc.
    Inventors: Michael T. Black, Martin K. Burnham, Jason C. Fedon, John E. Hodgson, David J. Knowles, Michael A. Lonetto, Richard O. Nicholas, Leslie M. Palmer, Julie M. Pratt, Raymond W. Reichard, Martin Rosenberg, Christopher M. Traini, Judith Ward, Richard L. Warren
  • Compounds
    Patent number: 7176299
    Abstract: This invention relates to newly identified Staphylococcal polynucleotides, polypeptides encoded by such polynucleotides, the uses of such polynucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides and recombinant host cells transformed with the polynucleotides. This invention also relates to inhibiting the biosynthesis or action of such polynucleotides or polypeptides and to the use of such inhibitors in therapy.
    Type: Grant
    Filed: June 23, 2005
    Date of Patent: February 13, 2007
    Assignee: Affinium Pharmaceuticals, Inc.
    Inventors: Michael Terence Black, Martin Karl Russell Burnham, Jason Craig Fedon, John Edward Hodgson, David Justin Charles Knowles, Michael Arthur Lonetto, Richard Oakley Nicholas, Leslie Marie Palmer, Julie M. Pratt, Raymond Winfield Reichard, Martin Rosenberg, Christopher Michael Traini, Judith M. Ward, Richard Lloyd Warren
  • ribG
    Publication number: 20040265872
    Abstract: The invention provides ribG polypeptides and polynucleotides encoding ribG polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ribG polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: April 14, 2004
    Publication date: December 30, 2004
    Applicant: SmithKline Beecham Corporation
    Inventors: Michael Terence Black, Martin Karl Russell Burnham, Jason Craig Fedon, John Edward Hodgson, David Justin Charles Knowles, Michael Arthur Lonetto, Richard Oakley Nicholas, Leslie Marie Palmer, Julie M. Pratt, Raymond Winfield Reichard, Martin Rosenberg, Christopher Michael Traini, Judith M. Ward, Richard Lloyd Warren
  • Compounds
    Patent number: 6465621
    Abstract: The invention provides ERA polypeptides and DNA (RNA) encoding ERA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ERA polypeptide for the protection against infection, particularly bacterial infections.
    Type: Grant
    Filed: August 3, 2000
    Date of Patent: October 15, 2002
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard O Nicholas, Martin Karl Russel Burnham, Julie M Pratt, Martin Rosenberg, Judith M Ward
  • ribB
    Patent number: 6448036
    Abstract: The invention provides ribB polypeptides and polynucleotides encoding ribB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ribB polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: November 25, 1997
    Date of Patent: September 10, 2002
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Michael Terence Black, Martin Karl Russell Burnham, Jason Craig Fedon, John Edward Hodgson, David Justin Charles Knowles, Michael Arthur Lonetto, Richard Oakley Nicholas, Leslie Marie Palmer, Julie M Pratt, Raymond Winfield Reichard, Martin Rosenberg, Christopher Michael Traini, Judith M Ward, Richard Lloyd Warren
  • Member of ATP dependent protease family, clpL
    Patent number: 6447773
    Abstract: The invention provides clpL polypeptides and DNA (RNA) encoding clpL polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: October 13, 1999
    Date of Patent: September 10, 2002
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard Oakley Nicholas, Martin Karl Russel Burnham, Julie M Pratt, Martin Rosenberg, Judith M Ward, Andrew Fosberry, Elizabeth J Lawlor
  • Novel prokaryotic polynucleotides, polypeptides and their uses
    Publication number: 20020082234
    Abstract: The invention provides novel polypeptides and polynucleotides encoding such polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing such polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: August 27, 2001
    Publication date: June 27, 2002
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard O. Nicholas, Martin Karl Russel Burnham, Julie M. Pratt, Martin Rosenberg, Judith M. Ward, Michael Arthur Lonetto
  • Novel glucosaminidase
    Publication number: 20020076766
    Abstract: The invention provides glucosaminidase polypeptides and DNA (RNA) encoding glucosaminidase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing glucosaminidase polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: January 25, 2001
    Publication date: June 20, 2002
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard O. Nicholas, Martin Karl Russel Burnham, Julie M. Pratt, Martin Rosenberg, Judith M. Ward, Simon J. Foster
  • Novel histidinol dehydrogenase
    Publication number: 20020064848
    Abstract: The invention provides histidinol dehydrogenase polypeptides and DNA (RNA) encoding histidinol dehydrogenase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing histidinol dehydrogenase polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: March 14, 2001
    Publication date: May 30, 2002
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard O. Nicholas, Martin Karl Russel Burnham, Julie M. Pratt, Martin Rosenberg, Judith M. Ward, Michael Arthur Lonetto, Patrick Vernon Warren
  • ama
    Publication number: 20020052472
    Abstract: The invention provides ama polypeptides and polynucleotides encoding ama polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ama polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: January 12, 2001
    Publication date: May 2, 2002
    Inventors: David T. Beattie, Robert L. Deresiewicz, Adrian M. Lowe, Michael A. Lonetto, John E. Hodgson, Richard O. Nicholas, Leslie Marie Palmer, Julie M. Pratt
  • Prokaryotic polynucleotides polypeptides and their uses
    Patent number: 6348582
    Abstract: The invention provides novel polypeptides and polynucleotides encoding such polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing such polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: September 23, 1997
    Date of Patent: February 19, 2002
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard O Nicholas, Martin Karl Russel Burnham, Julie M Pratt, Martin Rosenberg, Judith M Ward, Michael Arthur Lonetto
  • PAI
    Patent number: 6344540
    Abstract: The invention provides pai polypeptides and DNA (RNA) encoding pai polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pai polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: July 28, 1999
    Date of Patent: February 5, 2002
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard Oakley Nicholas, Martin Karl Russel Burnham, Julie M Pratt, Martin Rosenberg, Judith M Ward, Michael Arthur Lonetto, Patrick Vernon Warren
  • PhoH homolog
    Patent number: 6323336
    Abstract: The invention provides phoH homolog polypeptides and DNA (RNA) encoding phoH homolog polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing phoH homolog polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: May 28, 1999
    Date of Patent: November 27, 2001
    Assignee: SmithKline Beecham Corp.
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard Oakley Nicholas, Martin Karl Russel Burnham, Julie M Pratt, Martin Rosenberg, Judith M Ward, Michael Arthur Lonetto, Patrick Vernon Warren
  • GbpA
    Patent number: 6320036
    Abstract: The invention provides gbpA polypeptides and DNA (RNA) encoding gbpA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gbpA polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: May 13, 1999
    Date of Patent: November 20, 2001
    Assignee: SmithKline Beecham Corp.
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard Oakley Nicholas, Martin Karl Russel Burnham, Julie M Pratt, Martin Rosenberg, Judith M Ward, Michael Arthur Lonetto, Patrick Vernon Warren
  • Novel glucosaminidase
    Publication number: 20010039038
    Abstract: The invention provides glucosaminidase polypeptides and DNA (RNA) encoding glucosaminidase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing glucosaminidase polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: January 25, 2001
    Publication date: November 8, 2001
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard O. Nicholas, Martin Karl Russel Burnham, Julie M. Pratt, Martin Rosenberg, Judith M. Ward, Simon J. Foster
  • ribG
    Patent number: 6280735
    Abstract: The invention provides ribG polypeptides and polynucleotides encoding ribG polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ribG polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: August 6, 1999
    Date of Patent: August 28, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beechman plc
    Inventors: Michael Terence Black, Martin Karl Russell Burnham, Jason Craig Fedon, John Edward Hodgson, David Justin Charles Knowles, Michael Arthur Lonetto, Richard Oakley Nicholas, Leslie Marie Palmer, Julie M Pratt, Raymond Winfield Reichard, Martin Rosenberg, Christopher Michael Traini, Judith M Ward, Richard Lloyd Warren
  • Polynucleotides encoding GTP cyclohydrolase II (RIBA)
    Patent number: 6280971
    Abstract: The invention provides ribA polypeptides and polynucleotides encoding ribA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ribA polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: January 11, 1999
    Date of Patent: August 28, 2001
    Assignees: SmithKline Beecham Corporatiion, SmithKline Beecham plc
    Inventors: Min Wang, Judith M Ward, Richard Lloyd Warren, Richard Oakley Nicholas, Leslie Marie Palmer, Julie M Pratt, David Justin Charles Knowles, Michael Arthur Lonetto, Jeffrey Mooney, Michael Terence Black, Martin Karl Russell Burnham, Christine Debouck, Jason Craig Fedon, John Edward Hodgson, Deborah Dee Jaworski, Raymond Winfield Reichard, Martin Rosenberg, Christopher Michael Traini, Yi Y Zhong
  • ClpL
    Patent number: 6274376
    Abstract: The invention provides clpL polypeptides and DNA (RNA) encoding clpL polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing clpL polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: September 4, 1997
    Date of Patent: August 14, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard Oakley Nicholas, Martin Karl Russel Burnham, Julie M Pratt, Martin Rosenberg, Judith M Ward, Andrew Fosberry, Elizabeth J Lawlor
  • Ferrichrome transport ATP-binding protein
    Patent number: 6264955
    Abstract: The invention provides Ferrichrome transport ATP-Binding Protein polypeptides and DNA (RNA) encoding Ferrichrome transport ATP-Binding Protein polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Ferrichrome transport ATP-Binding Protein polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: December 31, 1998
    Date of Patent: July 24, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Julie M Pratt, Martin Rosenberg, Judith M Ward, Michael Arthur Lonetto, Patrick Vernon Warren, Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard O Nicholas, Martin Karl Russel Burnham