Abstract: The present invention provides a tin-free, room temperature curable silicone elastomer composition, wherein the uncured composition is a putty. The silicone elastomer composition comprises a) an end-capped base polymer, wherein the base polymer comprises a polysiloxane or mixture of polysiloxanes, and wherein the end-capped base polymer comprises terminal di-(C1-4)alkoxy silyl groups; b) at least one amorphous filler; c) 15.1 to 60 parts by weight of at least one spherical filler for each 100 parts by weight of base polymer; and d) a curing catalyst consisting of one or more selected from the group consisting of organic titanates and organic zirconates. The terminal dialkoxy silyl groups of the base polymer can be dimethoxy silyl groups. The at least one amorphous filler can be selected from the group consisting of fumed silica, fumed alumina, carbon black, precipitated silica, precipitated calcium carbonate, surface-treated calcium carbonate and mixtures thereof.

Abstract: The present invention provides a tin-free, room temperature curable silicone elastomer composition, wherein the uncured composition is a putty.

Abstract: The present invention provides a tin-free, room temperature curable silicone elastomer composition, wherein the uncured composition is a putty.

Abstract: The present invention relates to methods of culturing adherent cells, in particular adherent stem cells, to confluency at a liquid-liquid interface. The invention also provides cell culture systems useful in the culture of cells at liquid-liquid interfaces. The cell culture systems generally comprise an aqueous cell culture medium and an oil phase, there being a conditioning layer disposed between the cell culture medium and the oil phase comprising a peptide or polymer layer and a surfactant that assists in the culture of the adherent cells (in particular stem cells) at the interface between the two phases.

Abstract: The present invention provides a tin-free, room temperature curable silicone elastomer composition, wherein the uncured composition is a putty.

Abstract: The present invention provides a tin-free, room temperature curable silicone elastomer composition, wherein the uncured composition is a putty.

Abstract: A polymer having a number average molecular weight (Mn) of about 10 000 g/mol comprising a monomeric rigid moiety R and a monomeric flexible moiety F, wherein R comprises a main-chain polycyclic core and F has a main chain comprising a number of atoms sufficient for the transition temperature of the polymer to be lower than the degradation temperature of the polymer is provided. A method of manufacturing of same is also provided. Biomedical devices, scaffolds and supports for tissue engineering, delivery devices, textiles, moulds, vehicle parts, tubes, active disassembly devices, microactuators, toys and inflatable membranes comprising same are also described.

Abstract: A polymer having a number average molecular weight (Mn) of about 10 000 g/mol comprising a monomeric rigid moiety R and a monomeric flexible moiety F, wherein R comprises a main-chain polycyclic core and F has a main chain comprising a number of atoms sufficient for the transition temperature of the polymer to be lower than the degradation temperature of the polymer is provided. A method of manufacturing of same is also provided. Biomedical devices, scaffolds and supports for tissue engineering, delivery devices, textiles, moulds, vehicle parts, tubes, active disassembly devices, microactuators, toys and inflatable membranes comprising same are also described.