Patents by Inventor Julien Reboud
Julien Reboud has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11771846Abstract: A device is disclosed for the preparation of nebulised droplets, for inhalation. The device has: a surface acoustic wave (SAW) transmission surface; a SAW transducer adapted to generate and propagate SAWs along the SAW transmission surface; and an array of cavities opening at the SAW transmission surface for containing a liquid. In operation, SAWs propagating along the SAW transmission surface interact with the liquid in the cavities to produce nebulised droplets of the liquid. Operation of the device results in a nebulised plume of droplets of average diameter in the range 1-5 ?m.Type: GrantFiled: April 1, 2022Date of Patent: October 3, 2023Assignee: The University Court of the University of GlasgowInventors: Julien Reboud, Robert Wilson, Jonathan Cooper
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Publication number: 20220288329Abstract: A device is disclosed for the preparation of nebulised droplets, for inhalation. The device has: a surface acoustic wave (SAW) transmission surface; a SAW transducer adapted to generate and propagate SAWs along the SAW transmission surface; and an array of cavities opening at the SAW transmission surface for containing a liquid. In operation, SAWs propagating along the SAW transmission surface interact with the liquid in the cavities to produce nebulised droplets of the liquid. Operation of the device results in a nebulised plume of droplets of average diameter in the range 1-5 ?m.Type: ApplicationFiled: April 1, 2022Publication date: September 15, 2022Inventors: Julien Reboud, Robert Wilson, Jonathan Cooper
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Patent number: 11311686Abstract: A device is disclosed for the preparation of nebulised droplets, for inhalation. The device has: a surface acoustic wave (SAW) transmission surface; a SAW transducer adapted to generate and propagate SAWs along the SAW transmission surface; and an array of cavities opening at the SAW transmission surface for containing a liquid. In operation, SAWs propagating along the SAW transmission surface interact with the liquid in the cavities to produce nebulised droplets of the liquid. Operation of the device results in a nebulised plume of droplets of average diameter in the range 1-5 ?m.Type: GrantFiled: November 11, 2015Date of Patent: April 26, 2022Assignee: The University Court of the University of GlasgowInventors: Julien Reboud, Robert Wilson, Jonathan Cooper
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Publication number: 20190390250Abstract: Disclosed are methods and devices for fragmenting chains of nucleic acids (such as DNA) in a liquid sample. A liquid sample is provided, comprising chains of nucleic acids. A sample treatment device has a sample treatment zone. The liquid sample is contacted with the sample treatment zone. Surface acoustic waves (SAWs) are propagated along a surface of the sample treatment zone, or more generated acoustic waves are propagated to couple with the sample, and/or the sample is subjected to freeze-thaw cycling, in order to cause fragmentation of said chains of nucleic acids in the sample.Type: ApplicationFiled: October 10, 2017Publication date: December 26, 2019Inventors: Robert WILSON, Jonathan M. COOPER, Julien REBOUD
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Publication number: 20170333644Abstract: A device is disclosed for the preparation of nebulised droplets, for inhalation. The device has: a surface acoustic wave (SAW) transmission surface; a SAW transducer adapted to generate and propagate SAWs along the SAW transmission surface; and an array of cavities opening at the SAW transmission surface for containing a liquid. In operation, SAWs propagating along the SAW transmission surface interact with the liquid in the cavities to produce nebulised droplets of the liquid. Operation of the device results in a nebulised plume of droplets of average diameter in the range 1-5 ?m.Type: ApplicationFiled: November 11, 2015Publication date: November 23, 2017Inventors: Julien Reboud, Robert Wilson, Jonathan Cooper
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Patent number: 9751057Abstract: A method of using a fluidics apparatus for lysing a cell. In the method, the cell is placed in a fluid sample contacting a substrate surface. The method further includes providing surface acoustic waves (SAWs) at the substrate surface, causing cell lyses.Type: GrantFiled: May 27, 2016Date of Patent: September 5, 2017Assignee: The University Court of the University of GlasgowInventors: Rab Wilson, Jonathan M. Cooper, Julien Reboud
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Publication number: 20160325248Abstract: A fluidics apparatus is disclosed for manipulation of at least one fluid sample, typically in the form of a droplet. The apparatus has a substrate surface with a sample manipulation zone for location of the fluid sample. A transducer arrangement such as an interdigitated electrode structure on a piezoelectric body provides surface acoustic waves at the substrate surface for manipulation of the fluid sample. The substrate surface has an arrangement of surface acoustic wave scattering elements forming a phononic crystal structure for affecting the transmission, distribution and/or behaviour of surface acoustic waves at the substrate surface. Also disclosed is a method for lysing a cell. In this method, the cell is comprised in a fluid sample contacting a substrate surface, the method comprising providing surface acoustic waves at the substrate surface, such that the cell lyses.Type: ApplicationFiled: May 27, 2016Publication date: November 10, 2016Inventors: Rab Wilson, Jonathan M. Cooper, Julien Reboud
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Patent number: 9410873Abstract: A fluidics apparatus for manipulation of at least one fluid sample is disclosed. A manipulation surface locates the fluid sample. A surface acoustic wave (SAW) generation material layer is provided. This is a polycrystalline material, textured polycrystalline material, biaxially textured polycrystalline material, microcrystalline material, nanocrystalline material, amorphous material or composite material. A transducer electrode structure arranged at the SAW generation material layer provides SAWs at the manipulation surface for interaction with the fluid sample. The manipulation surface has a phononic structure, for affecting the transmission, distribution and/or behavior of SAWs at the manipulation surface. The apparatus is typically manufactured by reel-to-reel processes, to reduce the unit cost to a level at which the apparatus can be considered to be disposable after a single use.Type: GrantFiled: February 24, 2012Date of Patent: August 9, 2016Assignee: The University Court of the University of GlasgowInventors: Rab Wilson, Jonathan M. Cooper, Julien Reboud
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Patent number: 9375690Abstract: A fluidics apparatus is disclosed for manipulation of at least one fluid sample, typically in the form of a droplet. The apparatus has a substrate surface with a sample manipulation zone for location of the fluid sample. A transducer arrangement such as an interdigitated electrode structure on a piezoelectric body provides surface acoustic waves at the substrate surface for manipulation of the fluid sample. The substrate surface has an arrangement of surface acoustic wave scattering elements forming a phononic crystal structure for affecting the transmission, distribution and/or behavior of surface acoustic waves at the substrate surface. Also disclosed is a method for lysing a cell. In this method, the cell is comprised in a fluid sample contacting a substrate surface, the method comprising providing surface acoustic waves at the substrate surface, such that the cell lyses.Type: GrantFiled: August 24, 2010Date of Patent: June 28, 2016Assignee: The University Court of the University of GlasgowInventors: Rab Wilson, Jonathan M. Cooper, Julien Reboud
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Publication number: 20140083174Abstract: A device for generating a nebulized sample for detection of an analyte. The device includes a surface acoustic wave (SAW) transducer and a superstrate. The superstrate has a first surface for coupling with the SAW transducer and a second surface for receiving a fluid sample incorporating the analyte. The fluid sample is nebulized from the second surface. The superstrate is provided with an electrical connection extending from the second surface of the superstrate to provide a conducting path from a charge source to the second surface of the superstrate. The charge source may be the surface of the transducer or an external voltage source.Type: ApplicationFiled: May 18, 2012Publication date: March 27, 2014Inventors: Julien Reboud, Robert Wilson, Jonathan Cooper
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Publication number: 20130330247Abstract: A fluidics apparatus for manipulation of at least one fluid sample is disclosed. A manipulation surface locates the fluid sample. A surface acoustic wave (SAW) generation material layer is provided. This is a polycrystalline material, textured polycrystalline material, biaxially textured polycrystalline material, microcrystalline material, nanocrystalline material, amorphous material or composite material. A transducer electrode structure arranged at the SAW generation material layer provides SAWs at the manipulation surface for interaction with the fluid sample. The manipulation surface has a phononic structure, for affecting the transmission, distribution and/or behaviour of SAWs at the manipulation surface. The apparatus is typically manufactured by reel-to-reel processes, to reduce the unit cost to a level at which the apparatus can be considered to be disposable after a single use.Type: ApplicationFiled: February 24, 2012Publication date: December 12, 2013Applicant: The University Courrt of the University of GlasgowInventors: Rab Wilson, Jonathan M. Cooper, Julien Reboud
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Patent number: 8372657Abstract: According to various embodiments, a microfluidic system for detecting a biological entity in a sample volume is provided. The microfluidic system may include: a chamber configured to receive the sample volume, wherein the chamber includes a detection region for detecting the biological entity; a first port in fluid communication with the chamber; and a second port including a filter in fluid communication with the chamber; and wherein a fluid provided to the first port or the second port flows between the first port and the second port through the chamber.Type: GrantFiled: October 20, 2010Date of Patent: February 12, 2013Assignee: Agency For Science, Technology, and ResearchInventors: Julien Reboud, Linus Tzu-Hsiang Kao, Andre Yao-Kuang Chung, Shin Yun Ng, Yu Chen, Yan Ping Wang, Janice Hao Yuan Liaw, Kum Cheong Tang
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Patent number: 8323572Abstract: A measuring device includes a first substrate; and a second substrate bonded on the first substrate. The second substrate has at least two inflow ports, at least two outflow ports, and an injection port. The two inflow ports, the two outflow ports, and the injection port penetrate the second substrate. The first substrate includes partition wall portions opposing to each other, and forming a first cavity between the partition wall portions, and forming at least two second cavities close against one of the partition wall portions. Each second cavity is provided adjacent to the first cavity. Through holes are provided in the respective partition wall portions to connect the first cavity and the second cavity to each other, and the through holes are adapted to capture an object to-be-tested introduced in the first cavity.Type: GrantFiled: April 12, 2012Date of Patent: December 4, 2012Assignees: Panasonic Corporation, Agency for Science Technology and ResearchInventors: Masaya Nakatani, Levent Yobas, Julien Reboud
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Publication number: 20120213671Abstract: A measuring device includes a first substrate; and a second substrate bonded on the first substrate. The second substrate has at least two inflow ports, at least two outflow ports, and an injection port. The two inflow ports, the two outflow ports, and the injection port penetrate the second substrate. The first substrate includes partition wall portions opposing to each other, and forming a first cavity between the partition wall portions, and forming at least two second cavities close against one of the partition wall portions. Each second cavity is provided adjacent to the first cavity. Through holes are provided in the respective partition wall portions to connect the first cavity and the second cavity to each other, and the through holes are adapted to capture an object to-be-tested introduced in the first cavity.Type: ApplicationFiled: April 12, 2012Publication date: August 23, 2012Inventors: Masaya NAKATANI, Levent Yobas, Julien Reboud
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Publication number: 20120149126Abstract: A fluidics apparatus is disclosed for manipulation of at least one fluid sample, typically in the form of a droplet. The apparatus has a substrate surface with a sample manipulation zone for location of the fluid sample. A transducer arrangement such as an interdigitated electrode structure on a piezoelectric body provides surface acoustic waves at the substrate surface for manipulation of the fluid sample. The substrate surface has an arrangement of surface acoustic wave scattering elements forming a phononic crystal structure for affecting the transmission, distribution and/or behaviour of surface acoustic waves at the substrate surface. Also disclosed is a method for lysing a cell. In this method, the cell is comprised in a fluid sample contacting a substrate surface, the method comprising providing surface acoustic waves at the substrate surface, such that the cell lyses.Type: ApplicationFiled: August 24, 2010Publication date: June 14, 2012Applicant: THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOWInventors: Rab Wilson, Jonathan M. Cooper, Julien Reboud
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Publication number: 20110192726Abstract: There is presently provided a device for detecting an analyte particle in a sample. The device comprises a chamber having an interior surface upon which is located an electrode array. The electrode array comprises pairs of electrodes, each pair having an inner electrode and an outer electrode that substantially surrounds the inner electrode. Each pair of electrodes is coated with a capture molecule that recognises and binds the analyte particle that is to be identified and quantified. The device uses a combination of dielectrophoresis and impedance measurements to capture and measure analyte particles from a sample.Type: ApplicationFiled: September 1, 2009Publication date: August 11, 2011Inventors: Yu Chen, Julien Reboud, En Hou Philip Wong, Kyaw Thu Moe, Se Ngie Winston Shim, Qasem Ramadan, Kum Cheong Tang
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Publication number: 20110129931Abstract: According to various embodiments, a microfluidic system for detecting a biological entity in a sample volume is provided. The microfluidic system may include: a chamber configured to receive the sample volume, wherein the chamber includes a detection region for detecting the biological entity; a first port in fluid communication with the chamber; and a second port including a filter in fluid communication with the chamber; and wherein a fluid provided to the first port or the second port flows between the first port and the second port through the chamber.Type: ApplicationFiled: October 20, 2010Publication date: June 2, 2011Inventors: Julien Reboud, Linus Tzu-Hsiang Kao, Andre Yao-Kuang Chung, Shi Yun Ng, Yu Chen, Yan Ping Wang, Janice Hao Yuan Liaw
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Publication number: 20110117577Abstract: According to embodiments of the present invention, a microfluidic system for detecting a biological entity in a sample volume is provided. The microfluidic system includes: an inlet configured to receive the sample volume; at least one microchannel in fluid communication with the inlet; a magnetic trapping region comprising the at least one microchannel; at least one detection region in fluid communication with the magnetic trapping region for detecting the biological entity to be detected; and at least one outlet in fluid communication with the at least one detection region.Type: ApplicationFiled: October 20, 2010Publication date: May 19, 2011Inventors: Julien Reboud, Hongmiao Ji, Kokchuan Lee, Huimin Lim
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Patent number: 7785890Abstract: A method and device for analysis of reaction media containing one or more cells. This method and device can be used to perform an automated high-throughput analysis.Type: GrantFiled: July 9, 2004Date of Patent: August 31, 2010Assignee: Commissariat A L'Energie AtomiqueInventors: Julien Reboud, Béatrice Schaack, François Chatelain
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Publication number: 20070065946Abstract: The invention relates to a method and device for the analysis of reaction media comprising one or more cells, which can be used to perform an automated high-throughput analysis.Type: ApplicationFiled: July 9, 2004Publication date: March 22, 2007Applicant: COMMISSARIAT AL'FNERGIE ATOMIQUEInventors: Julien Reboud, Beatrice Schaack, Francois Chatelain