Patents by Inventor Jun Ok Moon

Jun Ok Moon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9200300
    Abstract: The present invention relates to microorganisms of corynebacterium which can utilize xylose and to a method for producing L-lysine using same. More particularly, the present invention relates to microorganisms of corynebacterium which are modified, in which genes encoding xylose isomerase and xylulokinase which are xylose synthases are introduced to express the xylose synthase. The present invention also relates to a method for producing L-lysine, comprising a step of culturing the modified microorganisms of corynebacterium using xylose as a carbon source, and recovering L-lysine from the culture.
    Type: Grant
    Filed: January 10, 2013
    Date of Patent: December 1, 2015
    Assignee: CJ CHEILJEDANG CORPORATION
    Inventors: So Yeon Rah, Lan Huh, Chang Gyeom Kim, Kwang Ho Lee, Jun Ok Moon, Kyung Han Lee, Jin Seok Sung, Hyung Joon Kim
  • Patent number: 9109242
    Abstract: A variant of Corynebacterium shows activity greater than the endogenous activity of aspartate aminotransferase, aspartate kinase, aspartate semialdehyde dehydrogenase, dihydrodipicolinate synthase, dihydropicolinate reductase and diaminopimelate dicarboxylase and additionally pyruvate carboxylase. The variant is used in a method of producing L-lysine.
    Type: Grant
    Filed: September 17, 2007
    Date of Patent: August 18, 2015
    Assignee: CJ CHEILJEDANG CORPORATION
    Inventors: Young Hoon Park, Sang Jo Lim, Jun Ok Moon, So Yeon Rah, Hee Jong Lee, Jae Woo Jang, Do Hyun Kwon, Hyo Jin Kim, Jin Suck Sung, Hyung Joon Kim
  • Publication number: 20150104836
    Abstract: Provided is a method of producing L-amino acids by using a recombinant coryneform microorganism in which the expression of a target gene is weakened by using a gene transcription inhibition method.
    Type: Application
    Filed: September 26, 2014
    Publication date: April 16, 2015
    Inventors: Jun Ok MOON, Sang Jo LIM, Do Hyun KWON, Kwang Ho LEE, Hyun Won BAE
  • Publication number: 20150104837
    Abstract: The present invention relates to a novel isolated gene (polynucleotide) which encodes a protein having a biofilm formation inhibitory activity derived from Coryneform bacteria, a L-lysine-producing strain in which the polynucleotide is inactivated, and a method for producing L-lysine using the same.
    Type: Application
    Filed: October 14, 2014
    Publication date: April 16, 2015
    Inventors: Un Hwan HA, Yong Jae KIM, Jung Hoon LEE, Hee Sung SHIN, Jun Ok MOON, Hyung Joon KIM, Kwang Ho LEE
  • Publication number: 20150099281
    Abstract: The present invention relates to a modified polynucleotide encoding aspartate kinase (EC:2.7.2.4; hereinafter, referred to as LysC), transketolase (EC:2.2.1.1; hereinafter, referred to as Tkt) or pyruvate carboxylase (EC:6.4.1.1; hereinafter, referred to as Pyc), in which the initiation codon is substituted with ATG, a vector including the same, a microorganism transformed with the vector, and a method for producing L-lysine using the same.
    Type: Application
    Filed: December 21, 2012
    Publication date: April 9, 2015
    Inventors: Kwang Ho Lee, Sang Jo Lim, Jun Ok Moon, Jae Woo Jang, Su Jin Park, Sang Hee Park
  • Patent number: 8932861
    Abstract: The present invention relates to a transformation vector comprising the partial fragments of a gene encoding transposase, a microorganism transformed with the vector, and a method of producing lysine using the microorganism.
    Type: Grant
    Filed: November 21, 2012
    Date of Patent: January 13, 2015
    Assignee: CJ Cheiljedang Corporation
    Inventors: Jae-Woo Jang, Sang-Jo Lim, Jong-Soo Choi, Chul-Ha Kim, Jun-Ok Moon
  • Publication number: 20140377816
    Abstract: The present invention relates to microorganisms of corynebacterium which can utilize xylose and to a method for producing L-lysine using same. More particularly, the present invention relates to microorganisms of corynebacterium which are modified, in which genes encoding xylose isomerase and xylulokinase which are xylose synthases are introduced to express the xylose synthase. The present invention also relates to a method for producing L-lysine, comprising a step of culturing the modified microorganisms of corynebacterium using xylose as a carbon source, and recovering L-lysine from the culture.
    Type: Application
    Filed: January 10, 2013
    Publication date: December 25, 2014
    Inventors: So Yeon Rah, Lan Huh, Chang Gyeom Kim, Kwang Ho Lee, Jun Ok Moon, Kyung Han Lee, Jin Seok Sung, Hyung Joon Kim
  • Publication number: 20140356518
    Abstract: The present invention relates to a method for producing highly-concentrated L-amino acid and riboflavin simultaneously, and a microorganism for simultaneously producing L-amino acid and riboflavin. Specifically, the present invention relates to a modified microorganism for producing L-lysine or L-threonine, and riboflavin simultaneously, wherein the microorganism belonging to Corynebacterium sp. capable of producing L-lysine or L-threonine is modified by enhancing the activity of an enzyme family expressed by a rib operon which contains riboflavin biosynthesis gene family. Also, the present invention relates to a method for the simultaneous production of L-lysine or L-threonine, and riboflavin using the modified microorganism, and relates to a formulation or granular formulation, feed, and feed additive, containing L-lysine or L-threonine, and riboflavin produced from a culture medium of the modified microorganism.
    Type: Application
    Filed: October 17, 2012
    Publication date: December 4, 2014
    Inventors: Sang Hee Park, Jun Ok Moon, Sang Jo Lim, Do Hyun Kwon, Kyung Han Lee, Jin Suck Sung, Hyun Joon Kim
  • Publication number: 20140099680
    Abstract: The present invention relates to Corynebacterium sp. that is transformed with an Escherichia sp.-derived fructokinase gene to express fructokinase showing a sufficient activity of converting fructose into fructose-6-phosphate, thereby preventing unnecessary energy consumption, and a method for producing L-amino acids using the strain. The transformed Corynebacterium sp. of the present invention is able to express fructokinase from the Escherichia-derived fructokinase gene to prevent unnecessary energy consumption during fructose metabolism, leading to more cost-effective production of L-amino acids. Therefore, it can be widely used for the effective production of L-amino acids.
    Type: Application
    Filed: April 2, 2012
    Publication date: April 10, 2014
    Applicant: CJ CHEILJEDANG CORPORATION
    Inventors: Hyun Won Bae, Hyung Joon Kim, Jun Ok Moon, Jae Woo Jang, Jong Chul Kim, Tae Han Kim, Jin Suck Sung, Kyung Han Lee, Dae Cheol Kim, Hyo Jin Kim, Hyun Ae Bae, Sang Jo Lim
  • Patent number: 8440433
    Abstract: The present invention relates to a microorganism of Corynebacterium ssp. having enhanced expression of gene for encoding molybdenum cofactor biosynthesis enzyme A and a method for producing L-lysine using the same, which has effects on providing the production method of L-lysine using the Corynebacterium strain having enhanced productivity of L-lysine by intensifying expression of the moaA gene for encoding molybdnum cofactor biosynthesis enzyme A.
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: May 14, 2013
    Assignee: CJ Cheiljedang Corp.
    Inventors: Jun-Ok Moon, Jae-Woo Jang, So-Yeon Rah, Sang-Jo Lim, Jong-Soo Choi, Young-Hoon Park, Hyung-Joon Kim
  • Publication number: 20130102037
    Abstract: Disclosed is an L-lysine-producing microorganism having gluconate kinase activity weakened in comparison to the endogenous activity thereof, and methods provided for preparing the microorganism and for producing L-lysine using the same.
    Type: Application
    Filed: July 15, 2011
    Publication date: April 25, 2013
    Applicant: CJ CHEILJEDANG CORPORATION
    Inventors: Sang Jo Lim, Jun Ok Moon, Hyung Joon Kim, Jae Woo Jang, Jae Yong Cho
  • Patent number: 8426577
    Abstract: Disclosed are a nucleic acid molecule of Corynebacterium glutamicum origin, having an improved promoter activity, which is operably linked to operon encoding aspartate kinase and aspartate semialdehyde dehydrogense, a vector containing the same, a transformant transformed with the vector, and a method for the production of L-lysine using the transformant.
    Type: Grant
    Filed: January 23, 2009
    Date of Patent: April 23, 2013
    Assignee: CJ Cheiljedang Corporation
    Inventors: Chul Ha Kim, Jong Soo Choi, Sang Jo Lim, Hyung Joon Kim, Jun Ok Moon, Gey Hang Jeon, Jin Suk Sung
  • Patent number: 8361758
    Abstract: Provided are a microorganism of Corynebacterium genus capable of producing L-lysine and resistant to kanamycin, and a method of producing L-lysine using the same.
    Type: Grant
    Filed: May 7, 2010
    Date of Patent: January 29, 2013
    Assignee: CJ Cheiljedang Corporation
    Inventors: Young Hoon Park, Sang Jo Lim, Jun Ok Moon, Jin Suck Sung
  • Patent number: 8329434
    Abstract: The present invention provides a nucleic acid molecule having enhanced promoter activity, which is operably linked to a gene encoding aspartate aminotransferase and derived from Corynebacterium glutamicum, a vector comprising the nucleic acid molecule, a transformant transformed with the vector, and a method for producing L-lysine using the transformant.
    Type: Grant
    Filed: March 1, 2011
    Date of Patent: December 11, 2012
    Assignee: CJ Cheiljedang Corporation
    Inventors: Do Hyun Kwon, Hyung Joon Kim, Jae Woo Jang, Jun Ok Moon, Sang Jo Lim
  • Patent number: 8058036
    Abstract: The present invention relates to a microorganism of Corynebacterium genus having enhanced L-lysine productivity and a method of producing L-lysine using the same. More particularly, the present invention relates to a recombinant microorganism of Corynebacterium genus having enhanced L-lysine productivity by inactivating endogenous NCgl2534 gene having the amino acid sequence containing repeated lysine residues and a method of producing L-lysine using the same.
    Type: Grant
    Filed: December 28, 2007
    Date of Patent: November 15, 2011
    Assignee: CJ Cheiljedang Corporation
    Inventors: Hyun-min Koo, Sun-young Lee, Young-lyeol Yang, Hyo-jin Kim, Jun-ok Moon, Jae-woo Jang, Sang-jo Lim, Jong-soo Choi, Young-hoon Park
  • Patent number: 8048650
    Abstract: The present invention relates to a microorganism of Corynebacterium genus having enhanced L-lysine productivity and a method of producing L-lysine using the same. More particularly, the present invention relates to a recombinant microorganism of Corynebacterium genus having enhanced L-lysine productivity by inactivating endogenous NCgI 1090 gene having the amino acid sequence containing repeated aspartate residues and a method of producing L-lysine using the same.
    Type: Grant
    Filed: December 28, 2007
    Date of Patent: November 1, 2011
    Assignee: CJ Cheiljedang Corporation
    Inventors: Hyun-min Koo, Young-lyeol Yang, Hyo-jin Kim, Jun-ok Moon, Sang-jo Lim, Jong-soo Choi, Young-hoon Park
  • Publication number: 20110217741
    Abstract: The present invention provides a nucleic acid molecule having enhanced promoter activity, which is operably linked to a gene encoding aspartate aminotransferase and derived from Corynebacterium glutamicum, a vector comprising the nucleic acid molecule, a transformant transformed with the vector, and a method for producing L-lysine using the transformant.
    Type: Application
    Filed: March 1, 2011
    Publication date: September 8, 2011
    Applicant: CJ Cheiljedang Corporation
    Inventors: Do Hyun Kwon, Hyung Joon Kim, Jae Woo Jang, Jun Ok Moon, Sang Jo Lim
  • Publication number: 20100317067
    Abstract: Disclosed are a nucleic acid molecule of Corynebacterium glutamicum origin, having an improved promoter activity, which is operably linked to operon encoding aspartate kinase and aspartate semialdehyde dehydrogense, a vector containing the same, a transformant transformed with the vector, and a method for the production of L-lysine using the transformant.
    Type: Application
    Filed: January 23, 2009
    Publication date: December 16, 2010
    Applicant: CJ CHEILJEDANG CORPORATION
    Inventors: Chul Ha Kim, Jong Soo Choi, Sang Jo Lim, Hyung Joon Kim, Jun Ok Moon, Gey Hang Jeon, Jin Suk Sung
  • Patent number: 7851198
    Abstract: Disclosed is a novel L-lysine-inducible promoter nucleic acid molecule. Also disclosed are a vector containing the nucleic acid molecule, a host cell transformed with the vector, and a method of inducing expression of a target gene using the L-lysine-inducible promoter nucleic acid molecule.
    Type: Grant
    Filed: December 30, 2005
    Date of Patent: December 14, 2010
    Assignee: CJ Cheiljedang Corporation
    Inventors: Young Hoon Park, Hyun Min Koo, Jun Ok Moon, Seong Jun Kim, Hyo Jin Kim, Jung Kee Lee
  • Publication number: 20100273222
    Abstract: The present invention relates to a microorganism of Corynebacterium ssp. having enhanced expression of gene for encoding molybdenum cofactor biosynthesis enzyme A and a method for producing L-lysine using the same, which has effects on providing the production method of L-lysine using the Corynebacterium strain having enhanced productivity of L-lysine by intensifying expression of the moaA gene for encoding molybdnum cofactor biosynthesis enzyme A.
    Type: Application
    Filed: December 20, 2007
    Publication date: October 28, 2010
    Applicant: CJ CHEILJEDANG CORP.
    Inventors: Jun-Ok Moon, Jae-Woo Jang, So-Yeon Rah, Sang-Jo Lim, Jong-Soo Choi, Young-Hoon Park, Hyung-Joon Kim