Abstract: A base sequence detection apparatus is provided with a channel formed on a base sequence detection chip. Working electrodes are formed along the channel and include a probe immobilized thereon, counter electrodes are formed on the inner surface of the channel and, reference electrodes are formed on the inner surface of the channel. An introduction port introduces solution or air from the upstream side of the channel, a delivery port delivers the solution or air in the channel, and the sample is injected into the channel through a sample injection port.

Abstract: A connection structure for a resin pipe, in which leakage of fluid from between a metal pipe and the resin pipe fitted on the metal pipe is prevented for a long time. In the connection structure, at least two diameter-expanded sections (10, 11) are formed with a spacing on an end region of a metal pipe (1), the spacing between the two diameter-expanded sections (10, 11) functioning as a circumferential groove (12) in which a seal ring (SR) is received, and a resin tube (2) is fitted up to a position beyond a far side diameter-expanded section (11) of the two diameter-expanded sections (10, 11). A back ring (BR) is received in the circumferential groove (12) together with the seal ring (SR). The diameter-expanded sections (10, 11) of the metal tube (1) are formed by bulging or spool shape-forming process.

Abstract: A conductive detecting electrode (2), first blocking molecules (21) formed so as to cover a surface of the detecting electrode (2), the first blocking molecules decreasing adsorption of an intercalating agent to the surface of the detecting electrode (2), a target-complementary probe (23) immobilized to the detecting electrode (2) via a spacer member (22) comprising straight chain organic molecules, the target-complementary probe including a base sequence complementary to a target base sequence which is an object of detection, a conductive comparison electrode (3), and second blocking molecules (31) formed so as to cover a surface of the comparison electrode (3), the second blocking molecules decreasing adsorption of an intercalating agent to the surface of the comparison electrode (3), are provided.

Abstract: A base sequence detection apparatus is provided with a channel formed on a base sequence detection chip. Working electrodes are formed along the channel and include a probe immobilized thereon, counter electrodes are formed on the inner surface of the channel and, reference electrodes are formed on the inner surface of the channel. An introduction port introduces solution or air from the upstream side of the channel, a delivery port delivers the solution or air in the channel, and the sample is injected into the channel through a sample injection port.

Abstract: The present invention provides a method of detecting a nucleic acid amplification reaction, including the steps of adding a sample nucleic acid to a nucleic acid amplification buffer containing a reducing agent molecule, a redox molecule and a magnesium ion, to conduct an amplification reaction, measuring a reduction current produced by a reduction reaction of the reducing agent molecule with the redox molecule, under the conditions that when the amplification reaction of the sample nucleic acid has proceeded in the buffer, pyrophosphoric acid formed with the progress of amplification of the sample nucleic acid forms magnesium pyrophosphate with the magnesium ion, thereby decreasing a magnesium ion concentration of the buffer, and determining, from the magnitude of the reduction current measured above, whether the sample nucleic acid has been amplified or not.

Abstract: It is an object to provide electrical equipment eliminating the need to change the diameter of wires, and capable of improving assembly workability. Vehicle-mounted camera equipment 20 includes a circuit substrate 24 having a substrate connector 27, and a camera housing 25. An inside connector section 28 which is connected to the substrate connector 27 is provided integrally on an inner surface side of the camera housing 25, and an outside connector section 29 which is connected to an external connector 22 provided at the end of an external harness 21 is provided integrally on an outer surface side of the camera housing 25. Connector terminals 28a of the inside connector section 28 and connector terminals 29a of the outside connector section 29 are connected by connecting conductors 30, respectively, which are provided to be buried in the camera housing 25. The connector terminals 28a, 29a, and the connecting conductors 30 are made of a single conductive material.

Abstract: A diagnostic cassette for diagnosing an electrochemical measuring apparatus is disclosed. The electrochemical measuring apparatus is to perform electrochemical measurement on a sample in a sample cassette, which is attachable to and detachable from the electrochemical measuring apparatus, and includes a first working electrode interface, a first counter electrode interface, and a first reference electrode interface.

Abstract: The present invention provides a method of detecting a plurality of nucleic acid samples, includes a first step of preparing a nucleic acid sample detection device, a second step of preparing 1st to nth nucleic acid sample discrimination reagents, a third step of adding the 1st to nth nucleic acid sample discrimination reagents to 1st to nth nucleic acid samples respectively, a fourth step of injecting the 1st to nth nucleic acid samples into 1st to nth wells respectively, a fifth step of detecting the presence or absence of a reaction in positive control immobilization regions in the 1st to nth wells, and a sixth step of detecting the presence or absence of a reaction in detection nucleic acid probe immobilization regions in the 1st to nth wells.

Abstract: Deflectors (45b) of a nut (45) pick up balls (65) from a rolling passage (23b, 45f) in a tangential direction of the rolling passage and also in a direction of a lead angle thereof, and therefore the balls (65) can be picked up into a circulating passage (45c) without changing a direction of rolling of the balls, and therefore the smooth rolling can be secured, and operating sounds, vibrations, etc., can be kept to a low level.

Abstract: Under a state of a normal temperature, a pitch B2 of a feed nut 55, 65 is formed to be slightly larger than a pitch A2 of a feed shaft screw 53, 63. Accordingly, since the screw thread of the feed nut 55, 65 is pressed to the screw thread of the feed screw shaft 53, 63 with a small interference, there is no backlash between the feed screw shaft 53, 63 and the feed nut 55, 65 so that a smooth feeding operation can be carried out. Under a state of a low temperature, the feed nut 55, 65 contracts more than the feed screw shaft 53, 63. As a result, a pitch B1 of the feed nut 55, 65 has the substantially same dimension as that of a pitch A1 of the feed screw shaft 53, 63.

Abstract: A fastener (1) for joining together two members (5, 6) includes a ring main body (3), a plurality of projecting portions (4) which are provided on the ring main body in a circumferential direction at intervals, and a plurality of recessed portions (10) which are provided on the projecting portions, whereby when the two members move relative to each other, a stable frictional resisting force can be imparted.

Abstract: The present invention provides an all-solid-state reflection-controllable electrochromic device and a reflection-controllable member using that device, and the present invention relates to the all-solid-state reflection-controllable electrochromic device, which is a reflection-controllable device in which a multilayer thin film is formed on a transparent base material, wherein, at least a transparent conductive film layer, an ion storage layer, a solid electrolyte layer, a catalyst layer and a reflection-controllable layer using a magnesium-nickel based alloy thin film are formed on the base material; and, a reflection-controllable member incorporating this reflection-controllable electrochromic device, and it is possible to provide a reflection-controllable electrochromic device, having a novel multilayer structure with high transmissivity when transparent and capable of switching in a short period of time over a large surface area, and a reflection-controllable member incorporating this device.

Abstract: An organic electroluminescent element 1 according to the present invention includes: a substrate 2; a first electrode 3 formed on the substrate; an organic light-emitting layer 5 formed on the first electrode 3 so as to be brought into contact with the first electrode 3; and a second electrode 6 formed on the organic light-emitting layer 5, characterized in that an ion-doped surface onto which hydrogen ions or hydroxide ions are doped as dopant is provided in the vicinity of a contact interface B between the first electrode 3 and the organic light-emitting layer 5. By such characteristics, an organic electroluminescent element can be obtained, in which a low-voltage drive is made possible, and a long lifetime is realized.

Abstract: The invention provides a nucleic acid probe-immobilized substrate comprising a substrate and a nucleic acid probe containing a nucleotide sequence complementary to a target sequence and immobilized via a spacer onto the substrate, wherein upon hybridization, with the nucleic acid probe, of a target nucleic acid partially containing the target sequence, the spacer satisfies the relationship: X?Y wherein X is the length of the spacer and Y is the length of the target nucleic acid ranging from the end of the hybridized site at the side of the substrate to the end of the target nucleic acid at the side of the substrate.

Abstract: A nucleic acid detection cassette includes a cassette body, a nucleic acid detection region disposed in the cassette body, a first channel disposed in the cassette body, a second channel disposed in the cassette body. The nucleic acid detection region, in which a nucleic acid probe is immobilized, has a reagent inflow port, to which the first channel is connected, and a reagent outflow port, to which the second channel is connected. The nucleic acid detection cassette further includes a reagent injection portion which injects a reagent into the first channel, and a nucleic acid pretreatment region which is disposed in the first channel and which performs pretreatment for the detection of a nucleic acid. The first channel, the second channel, the nucleic acid detection region, the nucleic acid pretreatment region, and the reagent injection portion are sealed.

Abstract: In a nucleic acid detecting cassette in which a heating treatment chamber and a liquid delivery channel are constituted of a stationary member and flexible members, the heating treatment chamber is held by convex heating sections from both sides, whereby the heat treatment chamber and the liquid delivery channel are spatially separated from each other. Thus, it is possible to automatically execute a consistent process including nucleic acid amplification and other required treatments of the object sample as well as detection of a target nucleic acid.

Abstract: A nucleic acid detection device is provided with a closed channel formed of a first channel portion, through which a washing reagent storage section for storing a washing reagent for washing a detection section for nucleic acid detection communicates with the detection section, and a second channel portion through which a pretreatment section for nucleic acid treatment communicates with the detection section. The closed channel is connected with a gas inlet/outlet path for communication with the outside. The gas inlet/outlet path is blocked by a sealing mechanism before nucleic acid detection. In storing a pretreatment reagent and the washing reagent frozen, the gas inlet/outlet path is kept open and connected to the channel. Thus, there is provided a nucleic acid detection device having a structure for preventing leakage of nucleic acid samples to the outside and which can be stored for a long period of time with the reagents therein.

Abstract: Since a nut 45 is provided with paths for connecting rolling paths 23b, 45f and circulating paths 45c, that is, return paths 45d at end caps 45b, 45b attached to both ends of a main body 45a, a receiving portion for receiving power transmitted from an electric motor 35, that is, a driven gear portions 45e is provided at a center of an outer peripheral face on outer sides in a radius direction of the rolling paths and therefore, when power is transmitted from the electric motor 35 to the driven gear portion 45e, smooth operation can be carried out by restraining the nut 45 from being twisted.

Abstract: A nucleic acid cassette includes a main body in which first and second channels are formed. A sample containing a target nucleic acid is input in a sample chamber of the second channel via an injection port. In the cassette, a detecting part includes a detection chamber communicated to the first and second channels and a nucleic detection unit. The first channel has a first reagent reservoir storing a first reagent and a second reagent reservoir storing a second reagent. The first and second reagents reservoirs are separated by a gaseous body in the channel. The sample and the first and second reagents are supplied to the detecting part due to an action of a pump part communicated to the first and second channels.

Abstract: A wafer dividing method for dividing a wafer along a first set of plural streets extending parallel to each other, and a second set of plural streets extending parallel to each other and extending perpendicularly to the first set of the streets, the wafer having a plurality of rectangular regions defined on the face thereof by these streets. The wafer dividing method includes a groove forming step of forming grooves along the streets on the face of the wafer, and a grinding step of grinding the back of the wafer after the groove forming step. The grooves formed by the groove forming step include grooves having a first depth D1, and grooves having a second depth D2 which is greater than the first depth D1 (D2>D1).