Patents by Inventor Jun Qin

Jun Qin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GAMMA SECRETASE MODULATORS
    Publication number: 20110015190
    Abstract: This invention provides novel compounds that are modulators of gamma secretase. The compounds have the formula (I) wherein R2 is a fused bicyclic ring of the formula (II). Also disclosed are methods of modulating gamma secretase activity and methods of treating Alzheimer's disease using the compounds of formula (I).
    Type: Application
    Filed: December 4, 2008
    Publication date: January 20, 2011
    Inventors: Xianhai Huang, Anandan Palani, Jun Qin, Robert Aslanian, Zhaoning Zhu, William Greenlee, Hubert Josien, Wei Zhou, Xiaohong Zhou, Chad E. Bennett, Dmitri Pissarnitski, Mihirbaran Mandal, Pawan Dhondi, Troy McCracken, Thomas Bara, Zhiqiang Zhao, Duane Burnett, John Clader
  • GAMMA SECRETASE MODULATORS
    Publication number: 20100298359
    Abstract: This invention provides novel compounds that are modulators of gamma secretase. The compounds have the formula (I) wherein R2 is a fused bicyclic ring of the formula (II). Also disclosed are methods of modulating gamma secretase activity and methods of treating Alzheimer's disease using the compounds of formula (I).
    Type: Application
    Filed: December 4, 2008
    Publication date: November 25, 2010
    Inventors: Xianhai Huang, Anandan Palani, Jun Qin, Robert Aslanian, Zhaoning Zhu, William Greenlee
  • GAMMA SECRETASE MODULATORS
    Publication number: 20100247514
    Abstract: In its many embodiments, the present invention provides a novel class of heterocyclic compounds as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the central nervous system using such compounds or pharmaceutical compositions.
    Type: Application
    Filed: May 5, 2008
    Publication date: September 30, 2010
    Inventors: Zhaoning Zhu, William J. Greenlee, Zhong-Yue Sun, Gioconda Gallo, Theodros Asberom, Xianhai Huang, Xiaohong Zhu, Mark D. McBriar, Dmitri A. Pissarnitski, Zhiqiang Zhao, Ruo Xu, Hongmei Li, Anandan Palani, Johannes H. Voigt, Robert D. Mazzola, JR., John Clader, Hubert Josien, Jun Qin
  • NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20100227873
    Abstract: The present invention provides compounds of Formula (I): and pharmaceutically acceptable salts, solvates, esters, and tautomers thereof, wherein: Q is selected from the group consisting of: and L is selected from the group consisting of: pharmaceutically compositions comprising one or more compounds of formula (I), and methods of using the compounds of formula (I).
    Type: Application
    Filed: April 30, 2010
    Publication date: September 9, 2010
    Inventors: Anandan Palani, Jing Su, Dong Xiao, Xianhai Huang, Ashwin U. Rao, Xiao Chen, Haiqun Tang, Jun Qin, Ying R. Huang, Robert G. Aslanian, Brian A. McKittrick, Syliva J. Degrado
  • Heterocycles as nicotinic acid receptor agonists for the treatment of dyslipidemia
    Patent number: 7763623
    Abstract: A compound having the general structure of Formula (I): or a pharmaceutically acceptable salt, solvate, ester, or tautomer thereof, are useful in treating diseases, disorders, or conditions such as metabolic syndrome and dyslipidemia.
    Type: Grant
    Filed: January 17, 2007
    Date of Patent: July 27, 2010
    Assignee: Schering Corporation
    Inventors: Anandan Palani, Jun Qin, Dong Xiao, Ying R. Huang, Xiao Chen, Zhidan Liu, Sylvia J. Degrado, Robert G. Aslanian, Xianhai Huang
  • Nitrogen-containing heterocyclic compounds and methods of use thereof
    Patent number: 7750015
    Abstract: The present invention provides compounds of Formula (I): and pharmaceutically acceptable salts, solvates, esters, and tautomers thereof, wherein: Q is selected from the group consisting of: L is selected from the group consisting of: pharmaceutically compositions comprising one or more compounds of formula (I), and methods of using the compounds of formula (I).
    Type: Grant
    Filed: November 15, 2006
    Date of Patent: July 6, 2010
    Assignee: Schering Corporation
    Inventors: Anandan Palani, Dong Xiao, Xianhai Huang, Ashwin U. Rao, Xiao Chen, Jun Qin, Ying R. Huang, Robert G. Aslanian, Sylvia J. Degrado
  • Nitrogen-containing heterocyclic compounds and methods of use thereof
    Patent number: 7737155
    Abstract: The present invention provides compounds of Formula (I): and pharmaceutically acceptable salts, solvates, esters, and tautomers thereof, wherein: Q is selected from the group consisting of: and L is selected from the group consisting of: pharmaceutically compositions comprising one or more compounds of formula (I), and methods of using the compounds of formula (I).
    Type: Grant
    Filed: June 29, 2007
    Date of Patent: June 15, 2010
    Assignee: Schering Corporation
    Inventors: Anandan Palani, Dong Xiao, Xianhai Huang, Ashwin U. Rao, Xiao Chen, Jun Qin, Ying R. Huang, Robert G. Aslanian
  • Heterocycles as nicotinic acid receptor agonists for the treatment of dyslipidemia
    Patent number: 7723342
    Abstract: A compound having the general structure of Formula (I): or a pharmaceutically acceptable salt, solvate, ester, or tautomer thereof, wherein: Q is selected from the group consisting of: and L is selected from the group consisting of: or a pharmaceutically acceptable salt, solvate, ester, or tautomer thereof, are useful in treating diseases, disorders, or conditions such as metabolic syndrome and dyslipidemia.
    Type: Grant
    Filed: May 11, 2006
    Date of Patent: May 25, 2010
    Assignee: Schering Corporation
    Inventors: Anandan Palani, Jing Su, Dong Xiao, Xianhai Huang, Ashwin U. Rao, Xiao Chen, Haiqun Tang, Jun Qin, Ying Huang, Robert G. Aslanian, Brian A. McKittrick
  • NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20080019978
    Abstract: The present invention provides compounds of Formula (I): and pharmaceutically acceptable salts, solvates, esters, and tautomers thereof, wherein: Q is selected from the group consisting of: and L is selected from the group consisting of: pharmaceutically compositions comprising one or more compounds of formula (I), and methods of using the compounds of formula (I).
    Type: Application
    Filed: June 29, 2007
    Publication date: January 24, 2008
    Inventors: Anandan Palani, Jing Su, Dong Xiao, Xianhai Huang, Ashwin Rao, Xiao Chen, Haiqun Tang, Jun Qin, Ying Huang, Robert Aslanian, Brian McKittrick, Sylvia Degrado
  • Heterocycles as nicotinic acid receptor agonists for the treatment of dyslipidemia
    Publication number: 20070173495
    Abstract: A compound having the general structure of Formula (I): or a pharmaceutically acceptable salt, solvate, ester, or tautomer thereof, are useful in treating diseases, disorders, or conditions such as metabolic syndrome and dyslipidemia.
    Type: Application
    Filed: January 17, 2007
    Publication date: July 26, 2007
    Inventors: Anandan Palani, Jun Qin, Dong Xiao, Ying R. Huang, Xiao Chen, Zhidan Liu, Sylvia J. Degrado, Robert G. Aslanian, Xianhai Huang
  • Nitrogen-containing heterocyclic compounds and methods of use thereof
    Publication number: 20070066630
    Abstract: The present invention provides compounds of Formula (I): and pharmaceutically acceptable salts, solvates, esters, and tautomers thereof, wherein: Q is selected from the group consisting of: L is selected from the group consisting of: ?pharmaceutically compositions comprising one or more compounds of formula (I), and methods of using the compounds of formula (I).
    Type: Application
    Filed: November 15, 2006
    Publication date: March 22, 2007
    Inventors: Anandan Palani, Jing Su, Dong Xiao, Xianhai Huang, Ashwin Rao, Xiao Chen, Haiqun Tang, Jun Qin, Ying Huang, Robert Aslanian, Brian McKittrick, Sylvia Degrado
  • Heterocycles as nicotinic acid receptor agonists for the treatment of dyslipidemia
    Publication number: 20060264489
    Abstract: A compound having the general structure of Formula (I): or a pharmaceutically acceptable salt, solvate, ester, or tautomer thereof, wherein: Q is selected from the group consisting of: and L is selected from the group consisting of: or a pharmaceutically acceptable salt, solvate, ester, or tautomer thereof, are useful in treating diseases, disorders, or conditions such as metabolic syndrome and dyslipidemia.
    Type: Application
    Filed: May 11, 2006
    Publication date: November 23, 2006
    Inventors: Anandan Palani, Jing Su, Dong Xiao, Xianhai Huang, Ashwin Rao, Xiao Chen, Haiqun Tang, Jun Qin, Ying Huang, Robert Aslanian, Brian McKittrick