Patents by Inventor June Kaplow

June Kaplow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NUCLEAR FACTOR kappaB INDUCING FACTOR
    Publication number: 20110263831
    Abstract: The present invention is directed to nuclear factor ?B (NF?B)-inducing factor polypeptides (NFIF polypeptides) which are capable of inducing NF?B. The present invention includes within its scope NFIF polypeptides, including NFIF-14b and NFIF-7a, DNA, including cDNA, encoding these polypeptides, and expression vectors capable of expressing NFIF polypeptides. Also included are methods and compositions for increasing NF?B induction in a patient, methods and compositions for lowering NF?B induction in a patient, methods for inhibiting inflammation, and methods for manufacture of a medicament intended for the treatment and/or prevention of an NF?B-regulated inflammatory response. In addition, methods for determining whether a test compound inhibits or enhances the activity of NFIF polypeptides are provided.
    Type: Application
    Filed: June 10, 2011
    Publication date: October 27, 2011
    Applicant: AVENTIS PHARMACEUTICALS INC.
    Inventors: June KAPLOW, Thomas HAWS, Marie ROSIER, Patrice DENEFLE
  • NUCLEAR FACTOR kappaB INDUCING FACTOR
    Publication number: 20110245471
    Abstract: The present invention is directed to nuclear factor ?B (NF?B)-inducing factor polypeptides (NFIF polypeptides) which are capable of inducing NF?B. The present invention includes within its scope NFIF polypeptides, including NFIF-14b and NFIF-7a, DNA, including cDNA, encoding these polypeptides, and expression vectors capable of expressing NFIF polypeptides. Also included are methods and compositions for increasing NF?B induction in a patient, methods and compositions for lowering NF?B induction in a patient, methods for inhibiting inflammation, and methods for manufacutre of a medicament intended for the treatment and/or prevention of an NF?B-regulated inflammatory response. In addition, methods for determining whether a test compound inhibits or enhances the activity of NFIF polypeptides are provided.
    Type: Application
    Filed: June 10, 2011
    Publication date: October 6, 2011
    Applicant: AVENTIS PHARMACEUTICALS INC.
    Inventors: June KAPLOW, Thomas HAWS, Marie ROSIER, Patrice DENEFLE
  • Nuclear factor ?B inducing factor
    Patent number: 7972844
    Abstract: The present invention is directed to nuclear factor ?B (NF?B)-inducing factor polypeptides (NFIF polypeptides) which are capable of inducing NF?B. The present invention includes within its scope NFIF polypeptides, including NFIF-14b and NFIF-7a, DNA, including cDNA, encoding these polypeptides, and expression vectors capable of expressing NFIF polypeptides. Also included are methods and compositions for increasing NF?B induction in a patient, methods and compositions for lowering NF?B induction in a patient, methods for inhibiting inflammation, and methods for manufacture of a medicament intended for the treatment and/or prevention of an NF?B-regulated inflammatory response. In addition, methods for determining whether a test compound inhibits or enhances the activity of NFIF polypeptides are provided.
    Type: Grant
    Filed: February 15, 2006
    Date of Patent: July 5, 2011
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: June Kaplow, Thomas Haws, Marie Rosier, Patrice Denefle
  • Nuclear factor kappaB inducing factor
    Publication number: 20060223771
    Abstract: The present invention is directed to nuclear factor ?B (NF?B)-inducing factor polypeptides (NFIF polypeptides) which are capable of inducing NF?B. The present invention includes within its scope NFIF polypeptides, including NFIF-14b and NFIF-7a, DNA, including cDNA, encoding these polypeptides, and expression vectors capable of expressing NFIF polypeptides. Also included are methods and compositions for increasing NF?B induction in a patient, methods and compositions for lowering NF?B induction in a patient, methods for inhibiting inflammation, and methods for manufacutre of a medicament intended for the treatment and/or prevention of an NF?B-regulated inflammatory response. In addition, methods for determining whether a test compound inhibits or enhances the activity of NFIF polypeptides are provided.
    Type: Application
    Filed: February 15, 2006
    Publication date: October 5, 2006
    Applicant: Aventis Pharmaceuticals Products Inc.
    Inventors: June Kaplow, Thomas Haws, Marie Rosier, Patrice Denefle
  • Nuclear factor ?B inducing factor
    Patent number: 7041497
    Abstract: The present invention is directed to nuclear factor ?B (NF?B)-inducing factor polypeptides (NFIF polypeptides) which are capable of inducing NF?B. The present invention includes within its scope NFIF polypeptides, including NFIF-14b and NFIF-7a, DNA, including cDNA, encoding these polypeptides, and expression vectors capable of expressing NFIF polypeptides. Also included are methods and compositions for increasing NF?B induction in a patient, methods and compositions for lowering NF?B induction in a patient, methods for inhibiting inflammation, and methods for manufacture of a medicament intended for the treatment and/or prevention of an NF?B-regulated inflammatory response. In addition, methods for determining whether a test compound inhibits or enhances the activity of NFIF polypeptides are provided.
    Type: Grant
    Filed: March 30, 2001
    Date of Patent: May 9, 2006
    Assignee: Aventis Pharmaceuticals Products Inc.
    Inventors: June Kaplow, Thomas Haws, Marie Rosier, Patrice Denefle
  • Nuclear factor kappaB inducing factor
    Publication number: 20030170862
    Abstract: The present invention is directed to nuclear factor &kgr;B (NF&kgr;B)-inducing factor polypeptides (NFIF polypeptides) which are capable of inducing NF&kgr;B. The present invention includes within its scope NFIF polypeptides, including NFIF-14b and NFIF-7a, DNA, including cDNA, encoding these polypeptides, and expression vectors capable of expressing NFIF polypeptides. Also included are methods and compositions for increasing NF&kgr;B induction in a patient, methods and compositions for lowering NF&kgr;B induction in a patient, methods for inhibiting inflammation, and methods for manufacutre of a medicament intended for the treatment and/or prevention of an NF&kgr;B-regulated inflammatory response. In addition, methods for determining whether a test compound inhibits or enhances the activity of NFIF polypeptides are provided.
    Type: Application
    Filed: March 30, 2001
    Publication date: September 11, 2003
    Inventors: June Kaplow, Thomas Haws, Marie Rosier, Patrice Denefle