Abstract: A system and method is provided for detecting carpal tunnel syndrome in a patient, utilizing a vibratory waveform having a discrete frequency and a variable amplitude. The system includes control circuitry (22) for generating an electrical signal having the discrete frequency and a computer (14), including a memory, for controlling the circuitry (22) to vary the amplitude of the electrical signal and to generate associated amplitude data for storage in the memory. The system also includes a speaker (20) for converting the electrical signal into the vibratory waveform. A finger (34) of the patient rests directly on the cone (32) of the speaker (20), so that the vibratory waveform is applied directly to the finger (34).