Patents by Inventor Junichi Fukata

Junichi Fukata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for stimulating the secretion of ACTH by administration of IL-1B analogues
    Patent number: 5217714
    Abstract: A method for testing the inducibility of the hypothalamus to effect the secretion of andrenocorticotropic hormone comprising the steps of:(a) administering to a test subject a pharmaceutically effective amount of a derivative of human IL-1.beta. selected from the group consisting of human IL-1.beta. [7-153], human IL-1.beta. [1-148], human IL-1.beta. [Gly.sup.4 ], human IL-1.beta. [Leu.sup.93 ] and human IL-1.beta. [des Arg.sup.98]; and(b) measuring an increase in blood levels of at least one of adrenocorticotropic hormone, cortisol and corticotropin-releasing hormone,wherein the degree of increase in said blood levels of at least one of adrenocorticotropic hormone, cortisol and corticotropin-releasing hormone, corresponds to the degree of inducibility of the hypothalamus and is not substantially due to the induction of fever.
    Type: Grant
    Filed: September 19, 1989
    Date of Patent: June 8, 1993
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Hiroo Imura, Junichi Fukata, Yoshikatsu Hirai