Abstract: Systems and methods for linking real world activity with a location-based parallel reality experience are provided. In particular, a game server hosting a parallel reality experience receives position data from a client device of a user and determines whether the client device is at a real world landmark associated with a geographic area. Responsive to determining that the client device is at the real world landmark, the game server cause the client device to present content incentivizing the user to travel to a real world location in the geographic area. The game server determines whether the client device is within proximity of the real world location based on sensor data. Responsive to determining that the client device is within proximity of the real world location, the game server causes the client device to display the virtual element at a virtual world location corresponding to the real world location.

Abstract: A method of producing an image to aid detection of a change in progress of a disease in a patient is described. In the method, a first image of a distribution of a radioisotope in the patient is obtained. A second image of the distribution of the radioisotope in the patient is also obtained. At least one of the first and second images are then normalized (1:140). One of the images is warped to match the other image using a multiple-segment matching method (1:160). The first image is subtracted from the second image to form a subtraction image (1:220). Finally, the resulting subtraction image is displayed.

Abstract: A method, system, and computer program product for detecting at least one nodule in a medical image of a subject, including identifying, in the medical image, an anatomical region corresponding to at least a portion of an organ of interest; filtering the medical image to obtain a difference image; detecting, in the difference image, a first plurality of nodule candidates within the anatomical region; calculating respective nodule feature values of the first plurality of nodule candidates based on pixel values of at least one of the medical image and the difference image; removing false positive nodule candidates from the first plurality of nodule candidates based on the respective nodule feature values to obtain a second plurality of nodule candidates; and determining the at least one nodule by classifying each of the second plurality of nodule candidates as a nodule or a non-nodule based on at least one of the pixel values and the respective nodule feature values.

Abstract: A method, system, and computer program product for detecting at least one nodule in a medical image of a subject, including identifying, in the medical image, an anatomical region corresponding to at least a portion of an organ of interest; filtering the medical image to obtain a difference image; detecting, in the difference image, a first plurality of nodule candidates within the anatomical region; calculating respective nodule feature values of the first plurality of nodule candidates based on pixel values of at least one of the medical image and the difference image; removing false positive nodule candidates from the first plurality of nodule candidates based on the respective nodule feature values to obtain a second plurality of nodule candidates; and determining the at least one nodule by classifying each of the second plurality of nodule candidates as a nodule or a non-nodule based on at least one of the pixel values and the respective nodule feature values.