Patents by Inventor Junko Maeda
Junko Maeda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240131044Abstract: There is provided with a method for treating cancer, comprising administering a pharmaceutical composition to a patient with cancer in combination with an anti-cancer agent, the pharmaceutical composition. A compound is represented by General Formula (I) or a pharmaceutically acceptable salt thereof: where R1 is an acyl residue from a fatty acid.Type: ApplicationFiled: October 10, 2023Publication date: April 25, 2024Applicants: M.T.3, Inc., Colorado State University Research FoundationInventors: Takamitsu Kato, Junko Maeda, Tomohiro Haga, Takaomi Fukuhara
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Publication number: 20240102193Abstract: A cyanide-free gold electroplating solution for forming gold deposits contains bismuth and compact-packed via-filling deposit with a U-shaped stacked structure in cross section inside drilled holes. A gold electroplating solution includes 15 g/L of gold (I) sodium sulfite (as gold element), 15 g/L of sodium sulfate, 50 g/L of sodium sulfite, 10 mg/L of thallium formate (as thallium element), 50 mg/L of bismuth nitrate (as bismuth element) and 1 g/L of sodium phosphate.Type: ApplicationFiled: September 25, 2023Publication date: March 28, 2024Inventors: Koichiro INOUE, Junko TSUYUKI, Shinji MAEDA, Yusa IMANISHI
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Patent number: 11912679Abstract: [Problem] A compound which is useful as a STING inhibitor is provided. [Means for Solution] The present inventors have found aryl alkynamide derivatives having an inhibitory action on STING. The aryl alkynamide derivatives of the present invention have an inhibitory action on STING and can be used as an agent for treating an autoimmune disease, a neurodegenerative disease, a type I interferonopathy and/or other STING-mediated disease.Type: GrantFiled: September 26, 2023Date of Patent: February 27, 2024Assignees: Astellas Pharma, Inc., Mitobridge, Inc.Inventors: Junko Maeda, Ikumi Kuriwaki, Kai Kitamura, Yumi Yamashita, Kenichi Kakefuda, Akio Kamikawa, Kenji Negoro, Wataru Hamaguchi, Ryushi Seo, Jeffrey Ciavarri
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Publication number: 20240018113Abstract: [Problem] A compound which is useful as a STING inhibitor is provided. [Means for Solution] The present inventors have found aryl alkynamide derivatives having an inhibitory action on STING. The aryl alkynamide derivatives of the present invention have an inhibitory action on STING and can be used as an agent for treating an autoimmune disease, a neurodegenerative disease, a type I interferonopathy and/or other STING-mediated disease.Type: ApplicationFiled: September 26, 2023Publication date: January 18, 2024Applicants: Astellas Pharma, Inc., Mitobridge, Inc.Inventors: Junko Maeda, Ikumi Kuriwaki, Kai Kitamura, Yumi Yamashita, Kenichi Kakefuda, Akio Kamikawa, Kenji Negoro, Wataru Hamaguchi, Ryushi Seo, Jeffrey Ciavarri
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Publication number: 20230107277Abstract: The present invention addresses the problem of providing a pharmaceutical composition, in particular a compound suitable for prevention and/or treatment of an inflammatory disease and/or a neurodegenerative disease. The inventors of the present invention conducted extensive studies to find a compound that has suppressive action on NLRP3 inflammasome activation, and found that a substituted pyridazine compound has suppressive action on NLRP3 inflammasome activation, leading to completion of the present invention. The substituted pyridazine compound according to the present invention is expected to serve as a drug for prevention and/or treatment of an inflammatory disease and/or a neurodegenerative disease.Type: ApplicationFiled: March 26, 2021Publication date: April 6, 2023Inventors: Yusuke Inagaki, Takashi Kamikubo, Takahiro Nigawara, Junko Maeda, Susumu Yamaki, Ikumi Kuriwaki, Maiko Iida, Junichi Shishikura, Yuka Koizumi, Kenji Negoro, Takanori Koike, Kengo Saba
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Patent number: 10149472Abstract: Methods for stimulating the growth of non-leguminous plants are disclosed. In the methods, a non-leguminous plant, a part thereof, or a seedling or seed thereof is contacted with a composition comprising a chitooligosaccharide (CO) having the formula: R1 is —H, —CH3, —COCH3, —SO3H, —SO3Na, arabinose, methylated arabinose, fucose, or methylated fucose; R2 is —H, —CH3, —COCH3, —SO3H, —SO3Na, arabinose, methylated arabinose, fucose, or methylated fucose; each R3 is independently —H or —COCH3; and n is 0, 1, 2, 3, 4, 5 or 6. As non-limiting examples, the method can be used to stimulate production and yield in a cereal grain crop plant, such as rice, wheat or corn (maize).Type: GrantFiled: June 17, 2016Date of Patent: December 11, 2018Assignee: Wisconsin Alumni Research FoundationInventors: Jean-Michel Ané, Audrey Kalil, Junko Maeda
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Publication number: 20160366883Abstract: Methods for stimulating the growth of non-leguminous plants are disclosed. In the methods, a non-leguminous plant, a part thereof, or a seedling or seed thereof is contacted with a composition comprising a chitooligosaccharide (CO) having the formula: R1 is —H, —CH3, —COCH3, —SO3H, —SO3Na, arabinose, methylated arabinose, fucose, or methylated fucose; R2 is —H, —CH3, —COCH3, —SO3H, —SO3Na, arabinose, methylated arabinose, fucose, or methylated fucose; each R3 is independently —H or —COCH3; and n is 0, 1, 2, 3, 4, 5 or 6. As non-limiting examples, the method can be used to stimulate production and yield in a cereal grain crop plant, such as rice, wheat or corn (maize).Type: ApplicationFiled: June 17, 2016Publication date: December 22, 2016Inventors: Jean-Michel Ané, Audrey Kalil, Junko Maeda
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Patent number: 8912180Abstract: Provided is a novel compound which is an agent for treating rejection reactions in various organ transplantations, allergy diseases, autoimmune diseases, and hematologic tumor, and based on a PI3K? selective inhibitory action and/or an IL-2 production inhibitory action and/or a B cell proliferation inhibitory action (including an activation inhibitory action). The provided compound has a PI3K? selective inhibitory action, an IL-2 production inhibitory action, and/or a B cell proliferation inhibitory action, including an activation inhibitory action.Type: GrantFiled: February 8, 2013Date of Patent: December 16, 2014Assignee: Astellas Pharma Inc.Inventors: Fumie Takahashi, Sunao Imada, Toru Asano, Yoshihiro Kozuki, Junko Maeda, Koji Kato, Hidehiko Fukahori, Masahiko Shiwaku
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Patent number: 7816558Abstract: Provided is a triarylcarboxylic acid derivative, or an isomer, a prodrug, a hydrate, a solvate, a polymorph, or a pharmaceutically acceptable salt thereof, represented by the following general formula (I): wherein A is an optionally substituted aryl or heteroaryl, and B is an optionally substituted monocyclic heteroaryl; and a pharmaceutical composition comprising the same and a pharmaceutically acceptable carrier. The triarylcarboxylic acid derivative (I) exhibits potent xanthine oxidase inhibiting action and is therefore useful as a therapeutic agent for preventing or treating hyperuricemia, gout, inflammatory bowel disease, diabetic nephropathy and diabetic retinopathy.Type: GrantFiled: October 6, 2006Date of Patent: October 19, 2010Assignee: Astellas Pharma Inc.Inventors: Junji Sato, Kazuyuki Hattori, Hirokazu Kubota, Ryosuke Munakata, Toru Asano, Junko Maeda, Masakatsu Kawakami, Akio Kamikawa
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Publication number: 20090018104Abstract: Provided is a triarylcarboxylic acid derivative, or an isomer, a prodrug, a hydrate, a solvate, a polymorph, or a pharmaceutically acceptable salt thereof, represented by the following general formula (I): wherein A is an optionally substituted aryl or heteroaryl, and B is an optionally substituted monocyclic heteroaryl; and a pharmaceutical composition comprising the same and a pharmaceutically acceptable carrier. The triarylcarboxylic acid derivative (I) exhibits potent xanthine oxidase inhibiting action and is therefore useful as a therapeutic agent for preventing or treating hyperuricemia, gout, inflammatory bowel disease, diabetic nephropathy and diabetic retinopathy.Type: ApplicationFiled: October 6, 2006Publication date: January 15, 2009Applicant: Astellas Pharma Inc.Inventors: Junji Sato, Kazuyuki Hattori, Hirokazu Kubota, Ryosuke Munakata, Toru Asano, Junko Maeda, Masakatsu Kawakami, Akio Kamikawa
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Patent number: 6384682Abstract: A differential amplifier circuit comprising a pair of input MOS transistors, wherein inputs are supplied to the gates thereof, load circuits are connected to the drains thereof, and a current source is connected to the sources thereof, the current value of the current source is altered in line with variations in the characteristics of the input MOS transistors, thereby suppressing variations in the output level generated at the drain terminals of the input MOS transistors. In other words, unlike a conventional differential amplifier circuit, the current value of the current source is not kept to a uniform value, but rather is altered in accordance with the transistor characteristics generated by the manufacturing process.Type: GrantFiled: June 25, 2001Date of Patent: May 7, 2002Assignee: Fujitsu LimitedInventors: Junko Maeda, Naoaki Naka
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Publication number: 20010038311Abstract: A differential amplifier circuit comprising a pair of input MOS transistors, wherein inputs are supplied to the gates thereof, load circuits are connected to the drains thereof, and a current source is connected to the sources thereof, the current value of the current source is altered in line with variations in the characteristics of the input MOS transistors, thereby suppressing variations in the output level generated at the drain terminals of the input MOS transistors. In other words, unlike a conventional differential amplifier circuit, the current value of the current source is not kept to a uniform value, but rather is altered in accordance with the transistor characteristics generated by the manufacturing process.Type: ApplicationFiled: June 25, 2001Publication date: November 8, 2001Applicant: Fujitsu LimitedInventors: Junko Maeda, Naoaki Naka
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Patent number: 6275107Abstract: A differential amplifier circuit comprising a pair of input MOS transistors, wherein inputs are supplied to the gates thereof, load circuits are connected to the drains thereof, and a current source is connected to the sources thereof, the current value of the current source is altered in line with variations in the characteristics of the input MOS transistors, thereby suppressing variations in the output level generated at the drain terminals of the input MOS transistors. In other words, unlike a conventional differential amplifier circuit, the current value of the current source is not kept to a uniform value, but rather is altered in accordance with the transistor characteristics generated by the manufacturing process.Type: GrantFiled: September 17, 1999Date of Patent: August 14, 2001Assignee: Fujitisu LimitedInventors: Junko Maeda, Naoaki Naka