Patents by Inventor Juraj Koppel

Juraj Koppel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BENZOTHIAZOLYL THIENOPYRIDINE DERIVATIVES AND USES THEREOF
    Publication number: 20100298370
    Abstract: Novel benzothiazolyl thienopyridine compounds are provided and pharmaceutical compositions comprising benzothiazolyl thienopyridine compounds. The benzothiazolyl thienopyridine compounds are capable of inhibiting the interactions between vascular endothelial growth factor (VEGF) and heparan sulfate glycosaminoglycans (HS-GAGs), and are useful for prevention or treatment of diseases and disorders such as inflammation, autoimmune diseases and cancer.
    Type: Application
    Filed: August 14, 2007
    Publication date: November 25, 2010
    Inventors: Paul Gregor, Regina Zhuk, Nicolas Harris, Juraj Koppel
  • Pharmaceutical compositions comprising thieno[2,3-c]pyridine derivatives and use thereof
    Patent number: 7365080
    Abstract: The present invention provides thieno[2,3-C]pyridine derivatives, pharmaceutical compositions comprising the thieno[2,3-C]pyridine derivatives, and methods of use thereof. The compounds capable of inhibiting glycosaminoglycan (GAG) interactions with effector cell adhesion molecules (ECAM) are useful for treating diseases and disorders mediated by GAG-ECAMs interactions, particularly inflammatory and autoimmune diseases, viral diseases, cancer, and amyloid disorders.
    Type: Grant
    Filed: February 5, 2004
    Date of Patent: April 29, 2008
    Assignee: Rimonyx Pharmaceuticals Ltd.
    Inventors: Paul Gregor, Nicholas Harris, Juraj Koppel, Regina Zhuk
  • Pharmaceutical compositions comprising anti-inflammatory quinazolinecarboxamide derivatives
    Publication number: 20070191400
    Abstract: The present invention provides pharmaceutical compositions comprising quinazolinecarboxamide derivative, and certain novel quinazolinecarboxamide derivatives capable of inhibiting heparan sulfate-glycosaminoglycan (HS-GAGs) interactions with L-selectin, and useful in the prevention or treatment of various diseases, disorders and conditions mediated by HS-GAGs, particularly inflammatory and autoimmune diseases, viral diseases, cancer, and amyloid disorders.
    Type: Application
    Filed: March 24, 2005
    Publication date: August 16, 2007
    Applicant: Rimonyx Pharmaceuticals Ltd.
    Inventors: Paul Gregor, Nicholas Harris, Juraj Koppel, Regina Zhuk
  • Methods of screening for anti-inflammatory drugs and use thereof
    Publication number: 20060275214
    Abstract: The present invention relates to methods for screening small organic compounds capable of inhibiting the interactions of glycosaminoglycans with effector cell adhesion molecules. Specifically, the present invention provides a method for screening of small organic compounds, the compounds inhibit the interaction of heparin with L-selectin or P-selectin. The compounds identified by the methods of the invention are useful for treating inflammatory disorders, autoimmune diseases and cancer.
    Type: Application
    Filed: December 30, 2003
    Publication date: December 7, 2006
    Applicant: Rimonyx Pharmaceuticals LTD.
    Inventors: Paul Gregor, Nicholas Harris, Juraj Koppel
  • Pharmaceutical compositions comprising thieno[2,3-c]pyridine derivatives and use thereof
    Publication number: 20060135529
    Abstract: The present invention provides thieno[2,3-C]pyridine derivatives, pharmaceutical compositions comprising the thieno[2,3-C]pyridine derivatives, and methods of use thereof. The compounds capable of inhibiting glycosaminoglycan (GAG) interactions with effector cell adhesion molecules (ECAM) are useful for treating diseases and disorders mediated by GAG-ECAMs interactions, particularly inflammatory and autoimmune diseases, viral diseases, cancer, and amyloid disorders.
    Type: Application
    Filed: February 5, 2004
    Publication date: June 22, 2006
    Applicant: Rimonyx Pharmaceuticals Ltd
    Inventors: Paul Gregor, Nicholas Harris, Juraj Koppel, Regina Zhuk