Patents by Inventor Justin Ernst

Justin Ernst has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREX1 INHIBITORS AND USES THEREOF
    Publication number: 20230234943
    Abstract: Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds for inhibiting three prime repair exonuclease 1 (“TREX1”).
    Type: Application
    Filed: June 25, 2021
    Publication date: July 27, 2023
    Inventors: Thomas Walter DUBENSKY, JR., Ryan C. CLARK, Justin ERNST, Garrick K. PACKARD, Brett BUSCH, Joe Fred NAGAMIZO, Biswajit KALITA, Athisayamani Jeyaraj DURAISWAMY
  • Cytokine inhibitors
    Patent number: 7919617
    Abstract: The present invention provides low molecular weight compounds useful as cytokine inhibitors, and compositions thereof. In particular, compounds of the invention are useful as anti-inflammatory agents. There are further provided methods for the preparation of such agents and their use in preventing or treating conditions mediated by cytokines such as arthritis.
    Type: Grant
    Filed: December 14, 2009
    Date of Patent: April 5, 2011
    Assignee: iTherX Pharmaceuticals Inc.
    Inventors: Erik Boman, Susana Conde Ceide, Russell Dahl, Nancy G. J. Delaet, Justin Ernst, Antonio Garrido Montalban, Jeffrey Kahl, Christopher Larson, Stephen Miller, Hiroshi Nakanishi, Edward Roberts, Eddine Saiah, Robert Sullivan, Zhinjun Wang
  • Cytokine inhibitors
    Patent number: 7897599
    Abstract: The present invention provides low molecular weight compounds useful as cytokine inhibitors, and compositions thereof. In particular, compounds of the invention are useful as anti-inflammatory agents. There are further provided methods for the preparation of such agents and their use in preventing or treating conditions mediated by cytokines such as arthritis.
    Type: Grant
    Filed: December 14, 2009
    Date of Patent: March 1, 2011
    Assignee: iTherX Pharmaceuticals Inc.
    Inventors: Erik Boman, Susana Conde Ceide, Russell Dahl, Nancy G. J. Delaet, Justin Ernst, Antonio Garrido Montalban, Jeffrey Kahl, Christopher Larson, Stephen Miller, Hiroshi Nakanishi, Edward Roberts, Eddine Saiah, Robert Sullivan, Zhinjun Wang
  • ALPHA-KETOAMIDES AND DERIVATIVES THEREOF
    Publication number: 20100273797
    Abstract: The present invention provides low molecular weight compounds useful as cytokine inhibitors, and compositions thereof. In particular, compounds of the invention are useful as anti-inflammatory agents. There are further provided methods for the preparation of such agents and their use in preventing or treating conditions medicated by cytokines such as arthritis.
    Type: Application
    Filed: July 2, 2010
    Publication date: October 28, 2010
    Inventors: Erik Boman, Susana Conde Ceide, Russell Dahl, Nancy G. J. Delaet, Justin Ernst, Antonio Garrido Montalban, Jeffrey Kahl, Christopher Larson, Stephen Miller, Hiroshi Nakanishi, Edward Roberts, Eddine Saiah, Robert Sullivan, Zhijun Wang
  • Alpha-ketoamides and derivatives thereof
    Patent number: 7749999
    Abstract: The present invention provides low molecular weight compounds useful as cytokine inhibitors, and compositions thereof. In particular, compounds of the invention are useful as anti-inflammatory agents. There are further provided methods for the preparation of such agents and their use in preventing or treating conditions mediated by cytokines such as arthritis.
    Type: Grant
    Filed: September 10, 2004
    Date of Patent: July 6, 2010
    Assignee: Itherx Pharmaceuticals, Inc.
    Inventors: Erik Boman, Susana Conde Ceide, Russell Dahl, Nancy G. J. Delaet, Justin Ernst, Antonio Garrido Montalban, Hiroshi Nakanishi, Edward Roberts, Eddine Saiah, Robert Sullivan, Zhinjun Wang, Jeffrey Kahl, Christopher Larson
  • CYTOKINE INHIBITORS
    Publication number: 20100093734
    Abstract: The present invention provides low molecular weight compounds useful as cytokine inhibitors, and compositions thereof. In particular, compounds of the invention are useful as anti-inflammatory agents. There are further provided methods for the preparation of such agents and their use in preventing or treating conditions mediated by cytokines such as arthritis.
    Type: Application
    Filed: December 14, 2009
    Publication date: April 15, 2010
    Applicants: iTherx Pharmaceuticals, Inc.
    Inventors: Erik Boman, Susana Conde Ceide, Russell Dahl, Nancy G.J. Delaet, Justin Ernst, Antonio Garrido Montalban, Jeffrey Kahl, Christopher Larson, Stephen Miller, Hiroshi Nakanishi, Edward Roberts, Eddine Saiah, Robert Sullivan, Zhijun Wang
  • CYTOKINE INHIBITORS
    Publication number: 20100093735
    Abstract: The present invention provides low molecular weight compounds useful as cytokine inhibitors, and compositions thereof. In particular, compounds of the invention are useful as anti-inflammatory agents. There are further provided methods for the preparation of such agents and their use in preventing or treating conditions mediated by cytokines such as arthritis.
    Type: Application
    Filed: December 14, 2009
    Publication date: April 15, 2010
    Applicants: iTherx Pharmaceuticals, Inc.
    Inventors: Erik Boman, Susana Conde Ceide, Russell Dahl, Nancy G.J. Delaet, Justin Ernst, Antonio Garrido Montalban, Jeffrey Kahl, Christopher Larson, Stephen Miller, Hiroshi Nakanishi, Edward Roberts, Eddine Saiah, Robert Sullivan, Zhinjun Wang
  • Proteomimetic compounds and methods
    Patent number: 7312246
    Abstract: The present invention relates to compounds and pharmaceutical compositions which are proteonaimetic and to methods for inhibiting the interaction of an alpha-helical protein with another protein or binding site. Methods for treating diseases or conditions which are modulated through interactions between alpha helical proteins and their binding sites are other aspects of the invention. In particular, the invention relates to treatment of viral infections using terphenyl derivatives.
    Type: Grant
    Filed: January 25, 2005
    Date of Patent: December 25, 2007
    Assignee: Yale University
    Inventors: Andrew D. Hamilton, Justin Ernst, Brendan Orner
  • Proteomimetic compounds and methods
    Publication number: 20050215563
    Abstract: The present invention relates to compounds and pharmaceutical compositions which are proteomimetic and to methods for inhibiting the interaction of an alpha-helical protein with another protein or binding site. Methods for treating diseases or conditions which are modulated through interactions between alpha helical proteins and their binding sites are other aspects of the invention.
    Type: Application
    Filed: January 25, 2005
    Publication date: September 29, 2005
    Inventors: Andrew Hamilton, Justin Ernst, Brendan Orner
  • Cytokine inhibitors
    Publication number: 20050107399
    Abstract: The present invention provides low molecular weight compounds useful as cytokine inhibitors, and compositions thereof. In particular, compounds of the invention are useful as anti-inflammatory agents. There are further provided methods for the preparation of such agents and their use in preventing or treating conditions mediated by cytokines such as arthritis.
    Type: Application
    Filed: September 10, 2004
    Publication date: May 19, 2005
    Inventors: Erik Boman, Susana Ceide, Russell Dahl, Nancy Delaet, Justin Ernst, Antonio Montalban, Jeffrey Kahl, Christopher Larson, Stephen Miller, Hiroshi Nakanishi, Edward Roberts, Eddine Saiah, Robert Sullivan, Zhijun Wang
  • Proteomimetic compounds and methods
    Patent number: 6858600
    Abstract: The present invention relates to compounds and pharmaceutical compositions which are proteomimetic and to methods for inhibiting the interaction of an alpha-helical protein with another protein or binding site. Methods for treating diseases or conditions which are modulated through interactions between alpha helical proteins and their binding sites are other aspects of the invention.
    Type: Grant
    Filed: May 8, 2002
    Date of Patent: February 22, 2005
    Assignee: Yale University
    Inventors: Andrew D. Hamilton, Justin Ernst, Brendan P. Orner
  • Proteomimetic compounds and methods
    Publication number: 20030008882
    Abstract: The present invention relates to compounds and pharmaceutical compositions which are proteomimetic and to methods for inhibiting the interaction of an alpha-helical protein with another protein or binding site. Methods for treating diseases or conditions which are modulated through interactions between alpha helical proteins and their binding sites are other aspects of the invention.
    Type: Application
    Filed: May 8, 2002
    Publication date: January 9, 2003
    Inventors: Andrew D. Hamilton, Justin Ernst, Brendan P. Orner