Patents by Inventor Justin K. Weaver

Justin K. Weaver has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stereoselective bioconversion of aliphatic dinitriles into cyano carboxylic acids
    Patent number: 8304252
    Abstract: The present invention is directed to a regio-and stereoselective bioconversion of selected aliphatic dinitriles into corresponding cyanocarboxylic acids. More particularly, the present invention provides methods for the conversion of 2-isobutyl-succinonitrile into (S)-3 cyano-5-methylhexanoic acid, which is a useful intermediate in the synthesis of (S)-3(aminomethyl)-5-methylhexanoic acid (pregabalin). Pregabalin can be used for treating certain cerebral diseases, for example, in the treatment and prevention of seizure disorders, pain, and psychotic disorders.
    Type: Grant
    Filed: April 20, 2010
    Date of Patent: November 6, 2012
    Assignee: Pfizer Inc.
    Inventors: Michael P. Burns, Justin K. Weaver, John Wing Wong
  • Stereoselective Bioconversion of Aliphatic Dinitriles into Cyano Carboxylic Acids
    Publication number: 20100204503
    Abstract: The present invention is directed to a regio- and stereoselective bioconversion of selected aliphatic dinitriles into corresponding cyanocarboxylic acids. More particularly, the present invention provides methods for the conversion of 2-isobutyl-succinonitrile into (S)-3 cyano-5-methylhexanoic acid, which is a useful intermediate in the synthesis of (S)-3(aminomethyl)-5-methylhexanoic acid (pregabalin). Pregabalin can be used for treating certain cerebral diseases, for example, in the treatment and prevention of seizure disorders, pain, and psychotic disorders.
    Type: Application
    Filed: April 20, 2010
    Publication date: August 12, 2010
    Inventors: Michael P. Burns, Justin K. Weaver, John Wing Wong
  • Stereoselective bioconversion of aliphatic dinitriles into cyano carboxylic acids
    Patent number: 7727749
    Abstract: The present invention is directed to a regio- and stereoselective bioconversion of selected aliphatic dinitriles into corresponding cyanocarboxylic acids. More particularly, the present invention provides methods for the conversion of 2-isobutyl-succinonitrile into (S)-3 cyano-5-methylhexanoic acid, which is a useful intermediate in the synthesis of (S)-3(aminomethyl)-5-methylhexanoic acid (pregabalin). Pregabalin can be used for treating certain cerebral diseases, for example, in the treatment and prevention of seizure disorders, pain, and psychotic disorders.
    Type: Grant
    Filed: April 1, 2005
    Date of Patent: June 1, 2010
    Assignee: Pfizer, Inc.
    Inventors: Michael P. Burns, Justin K. Weaver, John Wing Wong
  • Apparatus for treating cellulosic materials
    Patent number: 6176176
    Abstract: A process and screw in barrel apparatus (10) for expanding cellulosic materials is described. The expanded cellulosic material is useful as an animal feed and a nutrient source for fermentation processes.
    Type: Grant
    Filed: April 30, 1998
    Date of Patent: January 23, 2001
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Bruce E. Dale, Justin K. Weaver
  • Process for treating cellulosic materials
    Patent number: 6106888
    Abstract: A process and screw in barrel apparatus (10) for expanding cellulosic materials is described. The expanded cellulosic material is useful as an animal feed and a nutrient source for fermentation processes.
    Type: Grant
    Filed: January 19, 1999
    Date of Patent: August 22, 2000
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Bruce E. Dale, Justin K. Weaver