Patents by Inventor K. Pokharkar

K. Pokharkar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8344168
    Abstract: The present invention relates to a process for the preparation of steroidal 17?-carboxylic thioates. More particularly the present invention relates to a convenient and efficient synthesis of steroidal 17?-carboxylic thioates, such as fluticasone propionate I, using soluble mixed fluorides to introduce fluorine by displacing an appropriate leaving group X in compounds II resulting in selective and controlled fluorination. The present invention also relates to intermediates II and their preparation.
    Type: Grant
    Filed: December 8, 2008
    Date of Patent: January 1, 2013
    Assignee: Generics (UK) Limited
    Inventors: Vinayak G. Gore, Mahesh Gadakar, K. Pokharkar, V. Wakchure
  • Publication number: 20090177001
    Abstract: The present invention relates to a process for the preparation of steroidal 17?-carboxylic thioates. More particularly the present invention relates to a convenient and efficient synthesis of steroidal 17?-carboxylic thioates, such as fluticasone propionate I, using soluble mixed fluorides to introduce fluorine by displacing an appropriate leaving group X in compounds II resulting in selective and controlled fluorination. The present invention also relates to intermediates II and their preparation.
    Type: Application
    Filed: December 8, 2008
    Publication date: July 9, 2009
    Inventors: Vinayak G. Gore, Mahesh Gadakar, K. Pokharkar, V. Wakchure