Patents by Inventor Kai Deng

Kai Deng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230131867
    Abstract: The present invention relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, intermediates thereto, and uses thereof. QS-7 is a potent immuno-adjuvant that is significantly less toxic than QS-21, a related saponin that is currently the favored adjuvant in anticancer and antiviral vaccines. Tedious isolation and purification protocols have hindered the clinical development of QS-7. A novel semi-synthetic method is provided wherein a hydrolyzed prosapogenin mixture is used to synthesize QS-7, QS-21, and related analogs, greatly facilitating access to QS-7 and QS-21 analogs for preclinical and clinical evaluation.
    Type: Application
    Filed: September 19, 2022
    Publication date: April 27, 2023
    Inventors: David GIN, Michelle ADAMS, Kai DENG, Philip LIVINGSTON, Govindaswami RAGUPATHI, Eric CHEA, Alberto FERNANDEZ-TEJADA, Lars Ulrik NORDSTROEM, William WALKOWICZ, Jeffrey GARDNER, Derek TAN
  • Publication number: 20220403849
    Abstract: A control method for a centrifugal compressor and an air conditioning system. The control method for the centrifugal compressor includes: S100, when an inlet opening of the centrifugal compressor is below a first preset value, shutting down a drive motor of the centrifugal compressor; or S200, when the inlet opening of the centrifugal compressor is not below the first preset value, performing the following operations in a preset order: decreasing the inlet opening of the centrifugal compressor, and increasing a rotate speed of the centrifugal compressor.
    Type: Application
    Filed: June 10, 2022
    Publication date: December 22, 2022
    Inventors: Kai Deng, Vishnu Sishtla, Jun Cao, Yuchang Shao
  • Publication number: 20220404077
    Abstract: A refrigeration system includes a compressor, a condenser, a throttling device, and an evaporator, which are connected in sequence to form a cooling circuit, the refrigeration system further includes an oil recovery system which includes: an operation chamber, which includes a first port communicating with an oil-containing position in the refrigeration system through a first pipeline, and a second port communicating with a bearing chamber or a bearing lubrication pipeline of the compressor through a second pipeline; and a main piston in the operation chamber, the main piston reciprocating in the operation chamber to perform an extraction stroke and a discharge stroke; in the extraction stroke, an oil-containing refrigerant in the oil-containing position in the refrigeration system is extracted to the operation chamber; and in the discharge stroke, the oil-containing refrigerant in the operation chamber is delivered to the bearing chamber or the bearing lubrication pipeline of the compressor.
    Type: Application
    Filed: June 7, 2022
    Publication date: December 22, 2022
    Inventors: Zhen Guo, Kai Deng, Vishnu Sishtla, Yingqin Wu, Lei Yu
  • Publication number: 20220373231
    Abstract: A deflector for a condenser, the condenser has an inlet communicated with exhaust pipes of a compressor, and the deflector is provided at the inlet, the deflector includes: a flow guiding structure having a first tube section and a second tube section of increasing diameter, the second tube section being positioned below the first tube section and extending into the condenser when mounted in place; and a support assembly for fixing the flow guiding structure at the inlet, at least a part of the refrigerant gas flow flows through the interior of the first tube section, and at least another part of the refrigerant gas flow flows through the outer side of the first tube section.
    Type: Application
    Filed: May 17, 2022
    Publication date: November 24, 2022
    Inventors: Dongsheng Yang, Kai Deng, Yuling Shi, Hongyi Li, Keli Dong
  • Publication number: 20220373026
    Abstract: A winding method for radial magnetic bearing stator, a radial magnetic bearing stator and a radial magnetic bearing. The winding method for radial magnetic bearing stator includes: S110, sleeving a first formed stator winding on a first stator tooth of a stator core along a radial outward direction; S120, sleeving a second formed stator winding on a second stator tooth of the stator core along a radial outward direction; S130, a first coil of the first formed stator winding is connected in series with a second coil of the second formed stator winding; the first stator tooth is adjacent to the second stator tooth, and a stator slot is formed therebetween; and the coil number of the first formed stator winding is larger than that of the second formed stator winding.
    Type: Application
    Filed: May 18, 2022
    Publication date: November 24, 2022
    Inventors: Jiedong Li, Chong Cao, Jun Cao, Kai Deng
  • Patent number: 11447515
    Abstract: The present invention relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, intermediates thereto, and uses thereof. QS-7 is a potent immuno-adjuvant that is significantly less toxic than QS-21, a related saponin that is currently the favored adjuvant in anticancer and antiviral vaccines. Tedious isolation and purification protocols have hindered the clinical development of QS-7. A novel semi-synthetic method is provided wherein a hydrolyzed prosapogenin mixture is used to synthesize QS-7, QS-21, and related analogs, greatly facilitating access to QS-7 and QS-21 analogs for preclinical and clinical evaluation.
    Type: Grant
    Filed: June 16, 2017
    Date of Patent: September 20, 2022
    Assignee: SLOAN KETTERING INSTITUTE FOR CANCER RESEARCH
    Inventors: David Gin, Michelle Adams, Kai Deng, Philip Livingston, Govindaswami Ragupathi, Eric Chea, Alberto Fernandez-Tejada, Lars Ulrik Nordstroem, William Walkowicz, Jeffrey Gardner, Derek Tan
  • Patent number: 11415148
    Abstract: A system is provided and includes a compressor. The compressor further includes a diffuser frame, a gas or oil actuator and a drive system. The diffuser frame defines a first channel through which compressed fluids are flowable, a second channel intersecting the first channel and a third channel extending from the second channel. The gas or oil actuator includes a piston and a head integrally coupled to the piston. The head and the piston are disposable in the second and third channels, respectively. The piston is movable in forward or reverse directions through the third channel such that the head is movable through the second channel and into or out of the first channel, respectively. The drive system is at least partially disposable in the third channel and configured to drive forward and rearward movements of the piston.
    Type: Grant
    Filed: April 9, 2019
    Date of Patent: August 16, 2022
    Assignee: CARRIER CORPORATION
    Inventors: Kai Deng, Vishnu M. Sishtla
  • Publication number: 20220196299
    Abstract: A centrifugal compressor and a refrigerating device. The centrifugal compressor includes: a shell, which has a fluid inlet and a fluid outlet; a motor assembly including a stator and a rotor, the rotor including a vertically arranged rotor shaft; a centrifugal compression mechanism, an impeller of which is connected with the rotor shaft so as to be driven by the motor assembly, wherein the centrifugal compression mechanism is arranged downstream of the fluid inlet to receive fluid, compress and pressurize the fluid, and output the pressurized fluid in a direction away from the motor assembly; and a guide member, which receives the pressurized fluid from the centrifugal compression mechanism, and which defines a flow passage alone or together with a part of the shell, wherein the flow passage is configured such that the pressurized fluid from the centrifugal compression mechanism passes through and cools the motor assembly.
    Type: Application
    Filed: September 10, 2020
    Publication date: June 23, 2022
    Inventors: Tingcan Mi, Kai Deng, Lei Yu, Guangyu Shen, Fei Xie, Yuhui Kuang
  • Publication number: 20220034560
    Abstract: Refrigeration systems and control methods therefor are described. The refrigeration systems include a main circuit to connect, through a pipeline, a multi-stage compressor, a condenser, an economizer, a main throttling element, and an evaporator. An air supply branch is configured to connect to the air outlet of the economizer and the intermediate stage air inlet of the multi-stage compressor. A liquid injection branch is configured to connect to the intermediate stage air inlet of the multi-stage compressor from a section having a high-pressure liquid-phase refrigerant in the main circuit. Through the design of the liquid injection branch, the liquid-phase refrigerant can be introduced when vibration or noise of the unit exceeds a limit. The liquid-phase refrigerant, in the form of droplets, can effectively absorb the sound wave energy in the compressor pipeline to reduce an overall discharge pulsation of the compressor and reduce the noise and vibration of the condenser.
    Type: Application
    Filed: December 18, 2020
    Publication date: February 3, 2022
    Inventors: Kai Deng, Vishnu Sishtla
  • Publication number: 20220011026
    Abstract: A vapor compression system and method for operating the vapor compression system are provided. The vapor compression system includes a first compressor, a second compressor, a condenser, and at least one check valve disposed between the first compressor and the condenser. The method provides for the transmitting of a shutdown command to at least one of the first compressor and the second compressor, at least one of the first compressor and the second compressor including a rotating shaft and a magnetic bearing, the magnetic bearing having an active mode and an inactive mode, the magnetic bearing levitating the rotating shaft in the active mode. The method further provides for the monitoring of at least one of a rotational speed of the rotating shaft and a differential pressure over the check valve for a preset time, wherein the magnetic bearing remains in the active mode at least during the preset time.
    Type: Application
    Filed: July 1, 2021
    Publication date: January 13, 2022
    Inventors: Vishnu M. Sishtla, Jun Cao, Kai Deng
  • Patent number: 11187249
    Abstract: The present invention provides a silencer, including: a silencer housing having an annular plate-like structure, with an annular mounting chamber formed therein; a silencing pad disposed in the mounting chamber; and a positioning portion disposed on the silencer housing and used for fastening the silencer housing. The silencer according to the embodiment of the present invention has an integrated structure, and can desirably avoid the problem of mounting unflatness in a separated structure. Moreover, the silencing pad therein is disposed to surround the entire silencer, which can provide a sound absorption and noise reduction effect more efficiently.
    Type: Grant
    Filed: January 23, 2017
    Date of Patent: November 30, 2021
    Assignee: CARRIER CORPORATION
    Inventors: Vishnu M. Sishtla, Kai Deng, Zhanbo Du
  • Patent number: 11098934
    Abstract: The present utility model relates to a deflector for a condenser. The condenser has an inlet in communication with a compressor, and a deflector for guiding a refrigerant gas flow from the compressor is arranged in the condenser and at a position close to the inlet. The deflector is provided with a deflecting structure projecting toward the inlet, and the deflecting structure is configured as impermeable to the refrigerant gas flow. The present utility model further provides a condenser having the deflector for a condenser and a refrigeration system equipped with the condenser. The deflector for a condenser according to the present utility model not only can alleviate the impact of high-temperature high-pressure gas from the compressor but also can reduce noise and vibration.
    Type: Grant
    Filed: January 16, 2019
    Date of Patent: August 24, 2021
    Assignee: CARRIER CORPORATION
    Inventors: Michael A. Stark, Scott A. Nieforth, Kai Deng, Haiping Ding, Yuling Shi, HongYi Li
  • Publication number: 20210239372
    Abstract: A deflector for a condenser. The condenser has an inlet in communication with a compressor, and a deflector for guiding a refrigerant gas flow from the compressor is arranged in the condenser and at a position close to the inlet. The deflector is provided with a deflecting structure projecting toward the inlet, and the deflecting structure is configured as impermeable to the refrigerant gas flow.
    Type: Application
    Filed: April 21, 2021
    Publication date: August 5, 2021
    Inventors: Michael A. Stark, Scott A. Nieforth, Kai Deng, Haiping Ding, Yuling Shi, HongYi Li
  • Publication number: 20210190093
    Abstract: The present invention provides a silencer, including: a silencer housing having an annular plate-like structure, with an annular mounting chamber formed therein; a silencing pad disposed in the mounting chamber; and a positioning portion disposed on the silencer housing and used for fastening the silencer housing. The silencer according to the embodiment of the present invention has an integrated structure, and can desirably avoid the problem of mounting unflatness in a separated structure. Moreover, the silencing pad therein is disposed to surround the entire silencer, which can provide a sound absorption and noise reduction effect more efficiently.
    Type: Application
    Filed: January 23, 2017
    Publication date: June 24, 2021
    Inventors: Vishnu M. Sishtla, Kai Deng, Zhanbo Du
  • Publication number: 20210164494
    Abstract: A system is provided and includes a compressor. The compressor further includes a diffuser frame, a gas or oil actuator and a drive system. The diffuser frame defines a first channel through which compressed fluids are flowable, a second channel intersecting the first channel and a third channel extending from the second channel. The gas or oil actuator includes a piston and a head integrally coupled to the piston. The head and the piston are disposable in the second and third channels, respectively. The piston is movable in forward or reverse directions through the third channel such that the head is movable through the second channel and into or out of the first channel, respectively. The drive system is at least partially disposable in the third channel and configured to drive forward and rearward movements of the piston.
    Type: Application
    Filed: April 9, 2019
    Publication date: June 3, 2021
    Inventors: Kai Deng, Vishnu M. Sishtla
  • Patent number: 10970890
    Abstract: A maze-solving method includes converting extracted channel surface-shaped data into channel boundary lines; extending extension lines from two end points at a start point and at a terminal point, to two sides outside a maze, and constructing, outside the maze, a virtual connection line I and a virtual connection line II connecting base points on the extension lines of the start point and the terminal point; respectively enclosing a polygon I and a polygon II by means of the virtual connection line I and the channel boundary lines and by means of the virtual connection line II and the channel boundary lines, in which paths connecting the start point and the terminal point, between the polygon I and the polygon II are alternative solution paths for the maze; and selecting an alternative solution path with the shortest length as the optimal solution path for the maze.
    Type: Grant
    Filed: March 6, 2018
    Date of Patent: April 6, 2021
    Assignee: GUANGXI HUIGUIXIAN INFORMATION TECHNOLOGY CO., LTD.
    Inventors: Jinzhan Wei, Minghui Chen, Yuanlin Huang, Sheng Wang, Yiming Li, Xin Wei, Kai Deng, Jin Tao, Weirong Qin
  • Publication number: 20200368260
    Abstract: The present invention discloses the use of a benzopyran compound in the preparation of a product for regulating lipid metabolism, and a composition of the same, where the benzopyran compound includes petunidin-3-O-?-D glucoside and/or malvidin-3-O-?-D glucoside. It provides a new research direction for the preparation of the product for regulating lipid metabolism.
    Type: Application
    Filed: December 30, 2019
    Publication date: November 26, 2020
    Applicant: Northwest Institute of Plateau Biology, Chinese Academy of Sciences
    Inventors: Chenxu Ding, Kai Deng, Jing Meng, Na Hu
  • Patent number: 10823198
    Abstract: A diffuser for a centrifugal compressor and a centrifugal compressor having the same. The diffuser (100) comprises a drive component (110), a transmission assembly (120), an adjustment assembly (130), a spool valve assembly (140) and a rear wall (150); wherein the transmission assembly is used for transmitting power produced by the drive component to the adjustment assembly, the adjustment assembly is capable of circumferentially reciprocating with respect to the rear wall and driving the spool valve assembly to reciprocate axially; and wherein a rolling element (160) is provided between the adjustment assembly and the rear wall. Intervention of a mechanism for adjusting a flow passage width is better achieved by such an arrangement in combination with an existing configuration of the diffuser; and a low-friction fit between the adjustment assembly and the rear wall is achieved by the rolling element.
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: November 3, 2020
    Assignee: CARRIER CORPORATION
    Inventors: Vishnu M. Sishtla, Kai Deng, Zhanbo Du, Xili Liu, Scott A. Nieforth, Biao Shu, Danni Yuan
  • Patent number: 10822634
    Abstract: A method for rapid, high throughput screening of the activities of enzymes, especially ligninases and its enzyme cocktails, using nanostructure initiator mass spectrometry (NIMS) surfaces, substrates and methodology.
    Type: Grant
    Filed: April 27, 2017
    Date of Patent: November 3, 2020
    Assignees: The Regents of the University of California, National Technology & Engineering Solutions of Sandia, LLC
    Inventors: Trent R. Northen, Kai Deng
  • Publication number: 20190347835
    Abstract: Provided is a maze solving method based on a line-surface spatial relation, comprises the following steps: A. extracting channel surface-shaped data; B. converting the channel surface-shaped data into channel boundary lines; C. respectively extending extension lines from the two endpoints of the start point along the two outer sides of the maze, respectively extending extension lines from the two endpoints of the terminal point along the two outer sides of the maze, a base point is provided on the extension line, at the outside of the maze, constructing a virtual connecting line I which connects the base point of the start point and the base point of the terminal point, constructing a virtual connecting line II which connects the base point of the start point and the base point of the terminal point; D.
    Type: Application
    Filed: March 6, 2018
    Publication date: November 14, 2019
    Applicant: GUANGXI HUIGUIXIAN INFORMATION TECHNOLOGY CO., LTD.
    Inventors: Jinzhan WEI, Minghui CHEN, Yuanlin HUANG, Sheng WANG, Yiming LI, Xin WEI, Kai DENG, Jin TAO, Weirong QIN