Abstract: The present invention relates to substituted dioxane derivatives, pharmaceutical compositions containing them and their use in therapy, particularly in the treatment and/or prevention of neuronal and non-neuronal conditions having an association with mGluR4 function and/or in the treatment of obesity by means of mGluR4 modulation.

Abstract: A device for adjusting a motor vehicle valve train includes at least one camshaft with at least four cam elements arranged in an axially displaceable manner. In each case two of the cam elements that are adjacently situated are formed as a cam element group to be switched together.

Abstract: In a motor vehicle valve train adjustment device comprising at least one camshaft with at least two axially displaceable cam elements wherein at least one cam element has a cam track with a valve lift and a cam track with zero valve lift for a deactivation of at least one cylinder, and at least one other cam element of the at least two axially displaceable cam elements has a cam track with a first valve lift and a cam track with a second valve lift by which a cylinder which remains fueled during a partial cylinder deactivation is adapted to the at least one cylinder deactivation by special valve lift characteristics.

Abstract: A device for adjusting a motor vehicle valve train includes at least one camshaft with at least four cam elements arranged in an axially displaceable manner. In each case two of the cam elements that are adjacently situated are formed as a cam element group to be switched together.

Abstract: In a motor vehicle valve train adjustment device comprising at least one camshaft with at least two axially displaceable cam elements wherein at least one cam element has a cam track with a valve lift and a cam track with zero valve lift for a deactivation of at least one cylinder, and at least one other cam element of the at least two axially displaceable cam elements has a cam track with a first valve lift and a cam track with a second valve lift by which a cylinder which remains fueled during a partial cylinder deactivation is adapted to the at least one cylinder deactivation by special valve lift characteristics.

Abstract: In a hydraulic camshaft adjuster for a camshaft of an internal combustion engine and a method of assembling the camshaft adjuster including an inner body, which is connected to the camshaft in a rotationally fixed manner and has outwardly extending blades and an outer body which has inwardly projecting blades which form, together with the outwardly extending blades, at least one hydraulic medium chamber between two housing side covers connected to the outer body and operatively connected to a crankshaft of an engine so as to be driven thereby, a locking bolt is provided for locking the inner body in relation to the outer body with a predetermined play.

Abstract: In a sealing element, in particular for forming a seal between an impeller or rotary piston of a pivoting motor and a component surrounding the impeller, wherein the sealing element includes a base body with a first spring element integrally formed on a basic body for generating a first sealing pressure force, the basic body has an inner space to which a pressure medium is admitted in order to generate a second sealing pressure force intensifying the first sealing pressure force.

Abstract: In a camshaft adjuster for an internal combustion engine comprising a control valve having a control piston slidably supported in a valve housing, an operating unit for adjusting the angular position of the camshaft relative to a crankshaft of the engine and a drive unit with an electric motor and a transmission structure for actuating the control piston, the transmission is non-self-locking so that backward movement of the valve piston can be achieved by a backward force on the valve piston.

Abstract: In a locking device for a camshaft adjuster comprising a drive housing with a rotor with spaced rotor vanes disposed in the drive housing between circumferentially spaced axial walls projecting radially inwardly so as to form operating chambers at opposite sides of the rotor vanes to which hydraulic fluid can be selectively admitted for controlling the relative angular position between the rotor to which a camshaft is connected and the drive housing which is driven by the crankshaft of the engine, wherein locking bolts are provided for interlocking the drive housing and the vane rotor and disposed in one of the housing and the rotor elements while a recess is formed in the other for receiving the locking bolt in order to interlock the drive housing and the vane rotor, the locking bolt is arranged in the hydraulic fluid supply path to the operating chambers upstream of the operating chamber in such a way that hydraulic fluid admission to the operating chambers is controlled by the locking bolt and is admitted

Abstract: In a hydraulic camshaft adjuster for a camshaft of an internal combustion engine and a method of assembling the camshaft adjuster, with an inner body, which is connected to the camshaft in a rotationally fixed manner and has outwardly extending blades and an outer body which is mounted rotatably with respect to the camshaft and has inwardly projecting blades which form, together with the outwardly extending blades, at least one hydraulic medium chamber between two covers connected to the outer body which is operatively connected to a crankshaft of an engine so as to be driven thereby, and a locking device for locking the inner body in relation to the outer body by at least one bolt which is mounted in the inner body so as to extend into a locking cavity in one of the two covers, the camshaft adjuster has a base stop, and the locking cavity has an assembly stop providing for reliable assembly of the camshaft adjuster with minimal locking play and without the need for an adjusting procedure.

Abstract: In a hydraulic camshaft adjuster for an internal combustion engine including a hydraulic operating unit for adjusting the angular position of the camshaft relative to a camshaft drive by way of a hydraulic control valve with a valve housing in which a control piston is disposed for controlling the supply of hydraulic fluid to, and its removal from, the hydraulic operating unit and to which hydraulic fluid is supplied from the camshaft by way of a pressure channel which is formed into the valve housing so as to extend along the outer surface thereof and a sleeve tightly surrounds at least the part of the valve housing which includes the channel for tightly covering the channel.

Abstract: A camshaft adjuster for an internal combustion engine having hydraulic medium guides. The adjuster can include a setting unit that can be controlled by a control unit using these guides in the adjuster, wherein the setting unit is for adjusting an angle of a camshaft. This setting unit has an inner body coupled to the camshaft so as to rotate with it, and an outer body that is mounted to rotate relative to the camshaft via a drive connection which runs from a crankshaft to the camshaft. The camshaft has at least one insert part permanently inserted camshaft wherein these two components together form at least one hydraulic medium guide at least in partial regions over its axial length. This design is to create a camshaft adjuster which is in interaction with a camshaft having an insert part so that there is a simple and reliable supply of hydraulic medium to the camshaft adjuster and in particular to its control device.

Abstract: In a camshaft adjustment control device for an internal combustion engine arranged in the drive train for a camshaft, with an inner body connected to the camshaft and an outer body rotatable relative to the inner body, and a control space between the inner and the outer bodies to which hydraulic fluid can be supplied for adjusting the relative angular positions of the inner body connected to the camshaft and the outer body driven by the crankshaft, the inner body is mounted to the camshaft by a bolt having a central bore in which a control spool valve is disposed controlling the flow of fluid to and from the control space and a check valve is arranged in the supply lines of the hydraulic fluid to the control spool valve which check valve opens when a certain pressure is applied thereto.

Abstract: In a camshaft adjuster for an internal combustion engine comprising a control valve having a control piston slidably supported in a valve housing, an operating unit for adjusting the angular position of the camshaft relative to a crankshaft of the engine and a drive unit with an electric motor and a transmission structure for actuating the control piston, the transmission is non-self-locking so that backward movement of the valve piston can be achieved by a backward force on the valve piston.

Abstract: In a locking device for a camshaft adjuster comprising a drive housing with a rotor with spaced rotor vanes disposed in the drive housing between circumferentially spaced axial walls projecting radially inwardly so as to form operating chambers at opposite sides of the rotor vanes to which hydraulic fluid can be selectively admitted for controlling the relative angular position between the rotor to which a camshaft is connected and the drive housing which is driven by the crankshaft of the engine, wherein locking bolts are provided for interlocking the drive housing and the vane rotor and disposed in one of the housing and the rotor elements while a recess is formed in the other for receiving the locking bolt in order to interlock the drive housing and the vane rotor, the locking bolt is arranged in the hydraulic fluid supply path to the operating chambers upstream of the operating chamber in such a way that hydraulic fluid admission to the operating chambers is controlled by the locking bolt and is admitted

Abstract: In a sealing element, in particular for forming a seal between an impeller or rotary piston of a pivoting motor and a component surrounding the impeller, wherein the sealing element includes a base body with a first spring element integrally formed on a basic body for generating a first sealing pressure force, the basic body has an inner space to which a pressure medium is admitted in order to generate a second sealing pressure force intensifying the first sealing pressure force.

Abstract: In a device for changing the angle of rotation of a camshaft arranged in a cylinder head of an internal combustion engine relative to a drive wheel of the internal combustion engine, wherein a hydraulic adjusting arrangement is arranged between the drive wheel and the camshaft and is connected to a fluid circuit of the internal combustion engine, and wherein the fluid supply to the adjusting arrangement is controlled by an on/off valve, the on/off valve is mounted near the camshaft and is supplied with fluid via the camshaft.

Abstract: A camshaft adjuster for an internal combustion engine having hydraulic medium guides. The adjuster can include a setting unit that can be controlled by a control unit using these guides in the adjuster, wherein the setting unit is for adjusting an angle of a camshaft. This setting unit has an inner body coupled to the camshaft so as to rotate with it, and an outer body that is mounted to rotate relative to the camshaft via a drive connection which runs from a crankshaft to the camshaft. The camshaft has at least one insert part permanently inserted camshaft wherein these two components together form at least one hydraulic medium guide at least in partial regions over its axial length. This design is to create a camshaft adjuster which is in interaction with a camshaft having an insert part so that there is a simple and reliable supply of hydraulic medium to the camshaft adjuster and in particular to its control device.

Abstract: In a camshaft adjustment control device for an internal combustion engine arranged in the drive train for a camshaft, with an inner body connected to the camshaft and an outer body rotatable relative to the inner body, and a control space between the inner and the outer bodies to which hydraulic fluid can be supplied for adjusting the relative angular positions of the inner body connected to the camshaft and the outer body driven by the crankshaft, the inner body is mounted to the camshaft by a bolt having a central bore in which a control spool valve is disposed controlling the flow of fluid to and from the control space and a check valve is arranged in the supply lines of the hydraulic fluid to the control spool valve which check valve opens when a certain pressure is applied thereto.

Abstract: In a hydraulic camshaft adjuster for an internal combustion engine including a hydraulic operating unit for adjusting the angular position of the camshaft relative to a camshaft drive by way of a hydraulic control valve with a valve housing in which a control piston is disposed for controlling the supply of hydraulic fluid to, and its removal from, the hydraulic operating unit and to which hydraulic fluid is supplied from the camshaft by way of a pressure channel which is formed into the valve housing so as to extend along the outer surface thereof and a sleeve tightly surrounds at least the part of the valve housing which includes the channel for tightly covering the channel.