Patents by Inventor Kai-Uwe C. Matuschewski

Kai-Uwe C. Matuschewski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Live genetically attenuated malaria vaccine
    Patent number: 8168166
    Abstract: Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a liver-stage-specific gene function.
    Type: Grant
    Filed: May 6, 2008
    Date of Patent: May 1, 2012
    Assignees: Seattle Biomedical Research Institute, Walter and Eliza Hall Institute of Medical Research
    Inventors: Stefan H. I. Kappe, Kai-Uwe C. Matuschewski, Ann-Kristin Mueller, Kelley van Buskirk, Mehdi Labaied, Ahmed Sayed Ibrahim Aly, Alan Frederick Cowman, Alexander Gerd Maier
  • LIVE GENETICALLY ATTENUATED MALARIA VACCINE
    Publication number: 20110033502
    Abstract: Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a liver-stage-specific gene function.
    Type: Application
    Filed: May 6, 2008
    Publication date: February 10, 2011
    Inventors: Stefan H.I. Kappe, Kai-Uwe C. Matuschewski, Ann-Kristin Mueller, Kelley van Buskirk, Mehdi Labaied, Ahmed Sayed Ibrahim Aly, Alan Frederick Cowman, Alexander Gerd Maier
  • Live genetically engineered protozoan vaccine
    Patent number: 7722860
    Abstract: The invention provides methods for inducing an immune response in a vertebrate host against a protozoan parasite, comprising administering to the host a live protozoan parasite that is genetically engineered to disrupt a stage-specific gene function that is required by the protozoan parasite to establish a secondary infection in the vertebrate host. Representative protozoan parasites belong to the phyla Apicomplexa and Kinetoplastida. The vertebrate host may be a mammal or a bird.
    Type: Grant
    Filed: June 22, 2005
    Date of Patent: May 25, 2010
    Assignee: Seattle Biomedical Research Institute
    Inventors: Stefan H. I. Kappe, Kai-Uwe C. Matuschewski, Ann-Kristin Mueller
  • Live genetically attenuated malaria vaccine
    Patent number: 7718165
    Abstract: Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a liver-stage-specific gene function.
    Type: Grant
    Filed: December 20, 2004
    Date of Patent: May 18, 2010
    Assignees: Seattle Biomedical Research Institute, Ruprecht-Karls-Universitat Heidelberg
    Inventors: Stefan H. I. Kappe, Kai-Uwe C. Matuschewski, Ann-Kristin Mueller
  • Live Genetically Attenuated Malaria Vaccine
    Publication number: 20080032388
    Abstract: Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a liver-stage-specific gene function.
    Type: Application
    Filed: December 20, 2004
    Publication date: February 7, 2008
    Applicants: Seattle Biomedical Research Institute, Ruprecht-Karls-Universitat Heidelberg
    Inventors: Stefan H.I. Kappe, Kai-Uwe C. Matuschewski, Ann-Kristin Mueller
  • Live genetically attenuated malaria vaccine
    Patent number: 7261884
    Abstract: Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a liver-stage-specific gene function.
    Type: Grant
    Filed: August 30, 2006
    Date of Patent: August 28, 2007
    Assignees: Seattle Biomedical Research Institute, Ruprecht-Karls-Universitat Heidelberg
    Inventors: Stefan H. I. Kappe, Kai-Uwe C. Matuschewski, Ann-Kristin Mueller
  • Live genetically attenuated malaria vaccine
    Patent number: 7122179
    Abstract: Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a gene whose expression is up-regulated in liver stage parasites and whose function is not required for entry into hose hepatocytes.
    Type: Grant
    Filed: March 11, 2005
    Date of Patent: October 17, 2006
    Assignees: Seattle Biomedical Research Institute, Ruprecht-Karls-Universität Heidelberg
    Inventors: Stefan H. I. Kappe, Kai-Uwe C. Matuschewski, Ann-Kristin Mueller