Abstract: The present invention relates to Map4K1 inhibitors of formula (I) (I), wherein A, E, G, Q, R1, R2 and R4 have the same meaning as defined in the description, to pharmaceutical compositions and combinations comprising the compounds according to the invention, and to the prophylactic and therapeutic use of the inventive compounds, respectively to the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular for neoplastic disorders, respectively cancer or conditions with dysregulated immune responses or other disorders associated with aberrant MAP4K1 signaling, as a sole agent or in combination with other active ingredients.

Abstract: The present invention provides a system for data mapping and storing in digital three-dimensional oscilloscope, wherein the fixed coefficients, which are calculated according the parameters and settings of a digital oscilloscope, are stored into a fixed coefficient memory CO RAM, the fixed coefficients are outputted to N fractional operation units through N?1 D flip-flop delay units to multiply with the acquired data x(n) and then be accumulated, thus N fractional calculus results are obtained. In this way, N fractional calculus results can be obtained by performing L/N fractional calculus operations. N fractional calculus results are sent to a signal processing and display module, in which they are converted into a display data through a drawing thread, and the display data are sent to LCD for displaying, thus the fractional calculus operation and display of a input signal in a digital oscilloscope is realized.

Abstract: A taper-adjustable roller includes a support shaft, support sheets arranged circumferentially around the support shaft, and a first push member. Circumferential surfaces of the support sheets at sides of the support sheets facing away from the support shaft are assembled to form a roll surface. Each support sheet has a first end and a second end in an axial direction of the support shaft. The support sheets are swingable relative to the support shaft. The first push member is disposed on the support shaft, and is configured to push the first ends of the support sheets in a substantially radial direction, to move the first ends towards the support shaft and move the second ends away from the support shaft, or to move the first ends away from the support shaft and move the second ends towards the support shaft.

Abstract: A display device includes a first substrate, a light-emitting element, a light conversion layer, and a color filter layer. The light-emitting element is disposed on the first substrate. The light conversion layer is disposed on the light-emitting element. In addition, the color filter layer is overlapped the light-emitting element and the light conversion layer.

Abstract: Disclosed are systems, apparatuses, processes, and computer-readable media to capture images. A method of processing image data includes determining a first region of interest (ROI) in an image. The first ROI is associated with a first object. The method can include determining one or more image characteristics of the first ROI. The method can further include determining whether to perform an upsampling process on image data in the first ROI based on the one or more image characteristics of the first ROI.

Abstract: A method and system for metal artifacts correction are provided. The method may include obtaining an image to be processed including metal portion; determining initial projection data by performing data restoration on the metal portion of the image to be processed; determining target projection data by filtering the initial projection data; and determining a target image based on the target projection data.

Abstract: Disclosed a method for predicting permeability of a multi-mineral phase digital core based on deep learning. In the present disclosure, a three-dimensional digital core is constructed and a pore structure is randomly generated; after a plurality of multi-mineral digital core images is acquired by performing image segmentation on the three-dimensional digital core, permeability corresponding to each of the multi-mineral digital core images is acquired by simulation using multi-physics field simulation software and a multi-mineral digital core data set is constructed based on the plurality of multi-mineral digital core images and the permeability corresponding to each of the multi-mineral digital core images; an SE-ResNet18 convolutional neural network is constructed and trained with the multi-mineral digital core data set; and an image of a multi-mineral core to be predicted is input into the trained SE-ResNet18 convolutional neural network to determine the permeability of the multi-mineral core.

Abstract: A detection method of polyethylene glycol monomethyl ether residue in medicinal materials is provided, which belongs to a technical field of medicinal chemical component detection, and includes: detecting a residual amount of mPEG-2000 in 3000-3400 small-molecule mPEG-b-PDLLA by high-performance liquid chromatography with an evaporative light scattering detector. The present invention solves a problem that the copolymer polyethylene glycol monomethyl ether mPEG and the product polyethylene glycol monomethyl ether-polylactic acid block copolymer mPEG-b-PDLLA are difficult to be separated in the high-performance liquid chromatography and there is no UV absorption. The present invention also has high resolution, high sensitivity, sufficient reproducibility and sufficient selectivity.

Abstract: A rocker polishing apparatus for full-aperture deterministic polishing of a planar part includes a control system, a substrate, a lifting plate, a polishing module and a measuring module. The polishing module and the measuring module are arranged on the substrate. The lifting plate is arranged between the polishing module and the measuring module. The polishing module includes a rocker mechanism, a polishing pad surface dressing mechanism, a polishing pad surface profile measuring apparatus and a continuous polishing pad mechanism. The apparatus allows the material removal rate distribution of the planar part and the surface profile of the planar part be in the normalized mirror symmetry relationship by controlling the material removal rate distribution on the surface of the planar part, thereby implementing the deterministic polishing of the planar part and ensuring the efficient convergence of the surface profile of the planar part in the polishing process.

Abstract: Method and system for geometric correction based on image tracking, the method including: obtaining a plurality of projection images of a geometric model, each of the projection images including a projection marker corresponding to an original marker in the geometric model; obtaining an initial correspondence between the original markers in the geometric model and the projection markers in one of the projection images; determining a target correspondence between the original markers in the geometric model and the projection markers in the tracked projection image by tracking, based on a correlation of the projection images and the initial correspondence, the projection markers in the projection images; performing, based on the target correspondence, a geometric correction.

Abstract: A virtual machine management method and apparatus, a device, and a readable storage medium. The virtual machine management method is applied to a private cloud, and comprises: acquiring a SELinux label, the SELinux label comprising five elements: User, Role, Type, Sensitivity, and Category (S101); setting elements other than Category in the SELinux label as default values (S102); assigning different values to Category according to a preset Category variable combination so as to obtain multiple non-duplicate label groups (S103); and configuring each label group to a virtual machine in the private cloud, so that virtual machines configured with the same label group communicate with each other, and virtual machines configured with different label groups are isolated from each other (S104).

Abstract: Although silicon-oxide based particles have stable capacity and high cycling efficiency as anode active material, they are known to suffer significant capacity loss during the first battery cycles. The addition of lithium silicate may help to mitigate the initial capacity loss, but it has been difficult to produce such anodes. During battery manufacture cell components are exposed to water, and lithium silicate is water soluble. As lithium silicate dissolves, the pH of the water increases, which can etch silicon, degrading the anode active material. Such degradation can be mitigated by doping lithium silicate with multivalent elements or by converting some silicon to metal silicide before water processing. Doping of lithium silicate makes it less soluble in water. And metal silicide is not as easily etched as silicon.

Abstract: A fan assembly including a base, a fan, a light-emitting unit, and a lighting effect component is provided. The fan is rotatably disposed above the base, and includes a central part and multiple blades extending outwards from the central part, and each of the blades has a top surface away from the base. The light-emitting unit is disposed on the base and located between the base and the central part of the fan. The lighting effect component is disposed on the base and surrounds the light-emitting unit. A projection of the lighting effect component projected onto the base is greater than a projection of the fan projected onto the base. A height of the lighting effect component protruding from the base is less than a distance between the top surface of one of the blades and the base. The lighting effect component includes an inclined inner surface.

Abstract: Provided is an electronic smoking device accommodating a generic cigarette for generating less harmful aerosol and improving smoking flavor and quality. The electronic device comprises a cylindrical cigarette receiver, an extractor for retrieving smoking substances from cigarettes, a heating unit for baking the smoking substances instead of burning the substance, an air tight aerosol accumulation cavity to collect the vapor for a user to smoke, an electronic control circuit board and a power supply.

Abstract: A method for preparing products by electrochemical reductive amination and simultaneous oxidation of aldehyde-based biomass using non-precious metal catalysts is provided, which relates to a field of electrocatalysis. The preparing method includes: performing an electrochemical reaction in an electrolytic system with room temperature and atmospheric pressure (at a range of 25° C. to 30° C., 101 kPa) by taking an aldehyde compound and an amine compound as raw materials for reductive amination and oxidation of aldehyde-based biomass, and thereby obtaining the products. The electrolytic system includes a reaction substrate, an electrolyte, a solvent, an anode and a cathode. The anode is a phosphorylated hydrotalcite catalyst and the cathode is a Ti-based catalyst. The method uses no external oxidants and precious metal catalysts, which is clean, environmental and efficient.

Abstract: A cut tobacco heating device includes a tobacco mouthpiece; a tobacco rod including a heating cup disposed therein for holding cut tobacco; at least one sliding part disposed on the tobacco mouthpiece or the tobacco rod; and at least one connecting part, the tobacco mouthpiece and the tobacco rod being in rotatable connection through the at least one connecting part. By providing a connecting part and a sliding part between the tobacco rod and the tobacco mouthpiece, when in use, the sliding part and the connecting part are used to slide and rotate the tobacco mouthpiece to open the cut tobacco heating device. The cut tobacco can directly be put into the heating cup, then the tobacco mouthpiece is returned to its original position, and the cut tobacco in the cut tobacco heating device is heated to produce the smokes for being inhaled, which is convenient for operation.

Abstract: Battery cells according to embodiments of the present technology may include a cathode. The battery cells may include an anode including silicon particles. The silicon particles may be coated with a material physically and/or chemically bonding about the silicon particles to produce coated particles. The coated silicon particles may be formed into an electrode active material. The battery cells may include a separator disposed between the cathode and the anode. The battery cells may include an electrolyte.

Abstract: A fan assembly including a base, a fan, a light-emitting unit, and a lighting effect component is provided. The fan is rotatably disposed above the base, and includes a central part and multiple blades extending outwards from the central part, and each of the blades has a top surface away from the base. The light-emitting unit is disposed on the base and located between the base and the central part of the fan. The lighting effect component is disposed on the base and surrounds the light-emitting unit. A projection of the lighting effect component projected onto the base is greater than a projection of the fan projected onto the base. A height of the lighting effect component protruding from the base is less than a distance between the top surface of one of the blades and the base. The lighting effect component includes an inclined inner surface.

Abstract: Embodiments of the present disclosure relate to an apparatus and method for facilitating access to data in a distributed storage system by using a processing unit configured to collect information related to running status of the distributed storage system; obtain metadata related to data stored in the distributed storage system; in response to a request from a client, provide to the client the information related to running status and metadata related to data to be accessed; and extend storage nodes in the distributed storage system so that the client can directly access the storage nodes by using the information related to running status and the metadata related to data to be accessed. Other embodiments are also disclosed.