Patents by Inventor Kalyana Sundram P. Manickam

Kalyana Sundram P. Manickam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS COMPRISING EXTRACTS OR MATERIALS DERIVED FROM PALM OIL VEGETATION LIQUOR FOR INHIBITION OF VISION LOSS DUE TO ANGIOGENESIS AND METHOD OF PREPARATION THERE
    Publication number: 20150030710
    Abstract: The present invention relates generally to a composition comprising palm fruit juice for use in a method of preventing and inhibiting vision loss due to angiogenesis related diseases. The composition of the present invention aids to decrease in CNV size using confocal microscopy, in addition to reduction in macrophage infiltration using immune staining; decrease in VEGF-A-induced angiogenesis using established cornea pocket assay, inhibition of IKB-D phosphorylation in laser treated choroidal tissues and reduction in macrophage recruitment to CNV lesions.
    Type: Application
    Filed: August 5, 2014
    Publication date: January 29, 2015
    Inventors: Ali Hafezi MOGHADAM, Ravigadevi SAMBANTHAMURTHI, Yew Ai TAN, Kalyana Sundram P. MANICKAM, Kenneth C. HAYES, Zandi SOUSKA
  • COMPOSITION FOR USE IN THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES
    Publication number: 20140342023
    Abstract: The invention provides a composition the prevention and treatment of cardiovascular disease, wherein said composition compounds obtained from palm oil mill effluents, in particular from vegetative liquor from the milling of palm oil fruit.
    Type: Application
    Filed: July 2, 2014
    Publication date: November 20, 2014
    Inventors: Hjh Che Anishas HJ. Che Idris, Nagendran Balasundram, Ravigadevi Sambanthamurthi, Yew Ai Tan, Kalyana Sundram P. Manickam, Mohd Basri Wahid
  • COMPOSITION AND METHOD FOR IMPROVING VASCULAR HEALTH
    Publication number: 20140314875
    Abstract: The present invention relates to a composition for the use in improving vascular health, including treating and preventing vascular diseases and diseases related thereto, using a botanical extract of oil palm vegetation liquor from the palm oil milling process.
    Type: Application
    Filed: July 2, 2014
    Publication date: October 23, 2014
    Inventors: Mahinda Abeywardena, Ravigadevi Sambanthamurthi, Yew Ai Tan, Kalyana Sundram P. Manickam, Mohd Basri Wahid
  • Botanical extract from the aqueous stream of the palm oil milling process for the prevention and inhibition of oxidative stress and haemolysis in human red blood cells
    Patent number: 8790722
    Abstract: The invention provides a composition for the prevention and inhibition of oxidative stress and hemolysis in human red blood cell wherein said composition compounds obtained from the aqueous stream of palm oil milling (palm oil vegetation liquor), in particular from vegetative liquor from the milling of palm oil fruit.
    Type: Grant
    Filed: September 11, 2008
    Date of Patent: July 29, 2014
    Assignee: Malaysian Palm Oil Board
    Inventors: Nagendran Balasundram, Ravigadevi Sambanthamurthi, Yew Ai Tan, Kalyana Sundram P. Manickam, Mohd Basri bin Wahid, Samir Samman, Nihal S. Agar
  • Composition for use in the prevention and treatment of cardiovascular diseases
    Patent number: 8778419
    Abstract: The invention provides a composition the prevention and treatment of cardiovascular disease, wherein said composition compounds obtained from palm oil mill effluents, in particular from vegetative liquor from the milling of palm oil fruit.
    Type: Grant
    Filed: May 18, 2010
    Date of Patent: July 15, 2014
    Assignee: Malasian Palm Oil Board
    Inventors: Hjh Che Anishas HJ. Che Idris, Nagendran Balasundram, Ravigadevi Sambanthamurthi, Yew Ai Tan, Kalyana Sundram P. Manickam, Mohd Basri Wahid
  • Composition and method for improving vascular health
    Patent number: 8771764
    Abstract: The present invention relates to a composition for the use in improving vascular health, including treating and preventing vascular diseases and diseases related thereto, using a botanical extract of oil palm vegetation liquor from the palm oil milling process.
    Type: Grant
    Filed: June 8, 2010
    Date of Patent: July 8, 2014
    Assignees: Malaysian Palm Oil Board, Commonwealth Scientific and Industrial Research Organisation (CSIRO)
    Inventors: Mahinda Abeywardena, Ravigadevi Sambanthamurthi, Yew Ai Tan, Kalyana Sundram P. Manickam, Mohd Basri Wahid
  • COMPOSITIONS COMPRISING SHIKIMIC ACID OBTAINED FROM OIL PALM BASED MATERIALS AND METHOD OF PRODUCING THEREOF
    Publication number: 20130211136
    Abstract: The present invention provides compositions and method for production of shikimic acid based on extracts obtained from oil palm-based materials, and more particularly oil palm based waste materials and by-products. The method includes purifying shikimic acid from extracts comprising oil palm phenolics (OPP).
    Type: Application
    Filed: June 16, 2011
    Publication date: August 15, 2013
    Applicant: MALAYSIAN PALM OIL BOARD
    Inventors: Sambandan Tg, ChoKyun Rha, Ravigadevi Sambanthamurthi, Anthony J. Sinskey, Yew Ai Tan, Kalyana Sundram P. Manickam, Mohd Basri Wahid
  • COMPOSITION COMPRISING CAFFEOYLSHIKIMIC ACIDS, PROTOCATECHUIC ACID, HYDROXYTYROSOL, HYDROXYBENZOIC ACID AND THEIR DERIVATIVES AND METHOD OF PREPARATION THEREOF
    Publication number: 20120238773
    Abstract: A composition comprising caffeoylshikimic acids, protocatechuic acid, hydroxytyrosol, hydroxybenzoic acid, said caffeoylshikimic acids and their derivatives extracted from any part of oil palm including but not confined to the vegetation liquor of palm oil milling and palm oil mill effluent, and a method for use in the preparation of a composition containing caffeoylshikimic acids, protocatechuic acid, hydroxytyrosol, hydroxybenzoic acid, said caffeoylshikimic acids and their derivatives.
    Type: Application
    Filed: May 26, 2010
    Publication date: September 20, 2012
    Inventors: T.G. Sambandan, ChoKyun Rha, Anthony J. Sinskey, Ravigadevi Sambanthamurthi, Yew Ai Tan, Kalyana Sundram P. Manickam, Mohd Basri Wahid
  • Composition and Method for Improving Vascular Health
    Publication number: 20120141612
    Abstract: The present invention relates to a composition for the use in improving vascular health, including treating and preventing vascular diseases and diseases related thereto, using a botanical extract of oil palm vegetation liquor from the palm oil milling process.
    Type: Application
    Filed: June 8, 2010
    Publication date: June 7, 2012
    Applicants: Commonwealth Scientific and Industrial Research Organisation (CSIRO), Malaysian Palm Oil Board
    Inventors: Mahinda Abeywardena, Ravigadevi Sambanthamurthi, Yew Ai Tan, Kalyana Sundram P. Manickam, Mohd Basri Wahid
  • Composition for Use in the Prevention and Treatment of Cardiovascular Diseases
    Publication number: 20120121732
    Abstract: The invention provides a composition the prevention and treatment of cardiovascular disease, wherein said composition compounds obtained from palm oil mill effluents, in particular from vegetative liquor from the milling of palm oil fruit.
    Type: Application
    Filed: May 18, 2010
    Publication date: May 17, 2012
    Inventors: Hjh Che Anishas Hj. Che Idris, Nagendran Balasundram, Ravigadevi Sambanthamurthi, Yew Ai Tan, Kalyana Sundram P. Manickam, Mohd Basri Wahid
  • COMPOSITION COMPRISING OIL PALM PHENOLICS FOR USE IN PROVIDING NEUROPROTECTIVE EFFECTS AND COGNITIVE-ENHANCEMENT
    Publication number: 20120040029
    Abstract: The present invention relates to a composition comprising oil palm phenolics for use in providing neuroprotective effects and improving cognitive and motor functions abilities.
    Type: Application
    Filed: January 29, 2010
    Publication date: February 16, 2012
    Inventors: Ravigadevi S. Sambanthamurthi, Soon-Sen Leow, Yew Ai Tan, Kalyana Sundram P. Manickam, Mohd Basri Wahid
  • BOTANICAL EXTRACT FROM THE AQUEOUS STREAM OF THE PALM OIL MILLING PROCESS FOR THE PREVENTION AND INHIBITION OF OXIDATIVE STRESS AND HAEMOLYSIS IN HUMAN RED BLOOD CELLS
    Publication number: 20110052728
    Abstract: The invention provides a composition for the prevention and inhibition of oxidative stress and haemolysis in human red blood cell wherein said composition compounds obtained from the aqueous stream of palm oil milling (palm oil vegetation liquor), in particular from vegetative liquor from the milling of palm oil fruit.
    Type: Application
    Filed: September 11, 2008
    Publication date: March 3, 2011
    Inventors: Nagendran Balasundram, Ravigadevi Sambanthamurthi, Yew Ai Tan, Kalyana Sundram P. Manickam, Mohid Basri Bin Wahid, Sammir Samman, Nihal S. Agar
  • COMPOUNDS EXTRACTED FROM PALM OIL MILL EFFLUENT FOR THE TREATMENT OF CANCER, COMPOSITIONS THEREOF AND METHODS THEREWITH
    Publication number: 20100197780
    Abstract: The present invention describes a composition and methods for prevention and treatment of cancer comprising compounds extracted from Palm oil mill effluent. Also, the invention describes effective therapeutic dosages of the compounds and their combinations. The present invention can be prepared independently or as a combination product.
    Type: Application
    Filed: April 23, 2008
    Publication date: August 5, 2010
    Inventors: Kalyana Sundram P. Manickam, Ravigadevi Sambathamurthi, Yew Ai Tan, Mohd Basri Wahid, Soon Sen Leow