Abstract: A grafted nonwoven substrate is disclosed having average fiber sizes of 0.7 to 15 microns, and a void volume of 50 to 95%, and a polymer comprising anionic monomer units grafted to the surface of the nonwoven substrate. The article may be used as a filter element to purify or separate target materials, such as monoclonal antibodies (MAb), from a fluid mixture.

Abstract: A framed pleated air filter, including a non-self-supporting, compressible, pleated air filter media with a plurality of oppositely-facing pleats and with a plurality of upstream pleat tips and downstream pleat tips, the pleated air filter media further including a plurality of bridging filaments that are bonded to at least some of the upstream pleat tips. The framed pleated air filter does not include any support member on the downstream face of the pleated air filter media.

Abstract: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.

Abstract: Semi-interpenetrating polymeric networks are described. More specifically, the semi-interpenetrating polymeric networks include at least two polymers that are closely associated. The first polymer is an ionic polymer that is not crosslinked. The second polymer is a cross-linked polymer that can be either another ionic polymer or a non-ionic polymer. Methods of making the semi-interpenetrating polymeric networks, articles containing the semi-interpenetrating polymeric networks, and methods of using the semi-interpenetrating polymeric networks are also described. The semi-interpenetrating polymeric networks can function as ion exchange resins.

Abstract: A manually-operated gravity-flow water treatment cartridge for use in a portable water treatment device having a filtered water reservoir includes a housing comprising a framework defining a plurality of compartments that contain solid particulate water treatment media loosely arranged therein.

Abstract: A framed pleated air filter, including a non-self-supporting, compressible, pleated air filter media with a plurality of oppositely-facing pleats and with a plurality of upstream pleat tips and downstream pleat tips, the pleated air filter media further including a plurality of bridging filaments that are bonded to at least some of the upstream pleat tips. The framed pleated air filter does not include any support member on the downstream face of the pleated air filter media.

Abstract: A nestable framed pleated air filter, including a non-self-supporting, compressible, pleated air filter media with a plurality of oppositely-facing pleats and with a plurality of upstream pleat tips and downstream pleat tips and downstream pleat valleys, the pleated air filter media further including a plurality of bridging filaments that are bonded to at least some of the upstream pleat tips. The filter includes a frame with sidewalls that are angled so that the framed pleated air filter is nestable.

Abstract: A single pass simulated moving bed apparatus and methods are described for continuously separating a target molecule from a liquid mixture, using a simulated moving bed system. The simulated moving bed system includes a plurality of filter cartridge modules in serial fluid communication. Each filter cartridge module includes a volume of stationary phase particulates adjacent a porous substrate layer. The volume of stationary phase particulates has a bed height of less than 1 centimeter.

Abstract: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.

Abstract: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.

Abstract: A microbial detection article and methods of using the same, the article comprising: a base member comprising a self-supporting water impervious substrate with first and second generally opposed major surfaces; a filter assembly defining a filter assembly aperture therein, and having a composite filter body mounted across the filter assembly aperture; wherein the composite filter body comprises: a microporous membrane, and a water-absorbent layer in fluid communication with the microporous membrane; and a cover sheet.

Abstract: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.

Abstract: Porous polymeric resins, reaction mixtures and methods that can be used to prepare the porous polymeric resins, and uses of the porous polymeric resin are described. More specifically, the polymeric resins typically have a hierarchical porous structure plus reactive groups that can be used to interact with or react with a variety of different target compounds. The reactive groups can be selected from an acidic group or a salt thereof, an amino group or salt thereof, a hydroxyl group, an azlactone group, a glycidyl group, or a combination thereof.

Abstract: Porous polymeric resins, reaction mixtures and methods that can be used to prepare the porous polymeric resins, and uses of the porous polymeric resin are described. More specifically, the polymeric resins typically have a hierarchical porous structure plus reactive groups that can be used to interact with or react with a variety of different target compounds. The reactive groups can be selected from an acidic group or a salt thereof, an amino group or salt thereof, a hydroxyl group, an azlactone group, a glycidyl group, or a combination thereof.

Abstract: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.

Abstract: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.

Abstract: Polyethyleneimine and polyalkylene biguanide ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.

Abstract: A microbial detection article and methods of using the same, the article comprising: a base member comprising a self-supporting water impervious substrate with first and second generally opposed major surfaces; a filter assembly defining a filter assembly aperture therein, and having a composite filter body mounted across the filter assembly aperture; wherein the composite filter body comprises: a microporous membrane, and a water-absorbent layer in fluid communication with the microporous membrane; and a cover sheet.

Abstract: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.

Abstract: A manually-operated gravity-flow water treatment cartridge for use in a portable water treatment device having a filtered water reservoir includes a housing comprising a framework defining a plurality of compartments that contain solid particulate water treatment media loosely arranged therein.