Patent number: 7354949
Abstract: The present invention provides a therapeutic agent for bladder irritative symptoms associated with benign prostatic hyperplasia comprising, as an active ingredient, a tricyclic compound represented by formula (I): [wherein R1 represents a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkoxy or halogen; X1-X2-X3 represents CR5?CR6—CR7?CR8, N(O)m?CR6—CR7?CR8, CR5?CR6—N(O)m?CR8, CR5?CR6—CR7?N(O)m, CR5?CR6—O, CR5?CR6—S, O—CR7?CR8, S—CR7?CR8 or O—CR7?N; Y represents 13 CH2S—, —CH2SO—, —CH2SO2—, —CH2O—, —CH?CH—, —(CH2)p—, —SCH2—, —SOCH2—, —SO2CH2— or —OCH2—; and R2 represents a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkenyl, substituted or unsubstituted lower alkoxy, amino, mono(substituted or unsubstituted lower alkyl)-substituted amino, di(substituted or unsubstituted lower alkyl)-substituted amino, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted aralky
Type:
Grant
Filed:
March 29, 2002
Date of Patent:
April 8, 2008
Assignee:
Kyowa Hakko Kogyo Co., Ltd.
Inventors:
Tsuyoshi Yamagata, Kaoru Atsuki, Tetsuji Ohno, Shiro Shirakura, Akira Karasawa
