Patents by Inventor Kara L. Bren

Kara L. Bren has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for producing hydrogen using nanoparticle-catalyst mixtures
    Patent number: 10047443
    Abstract: Methods for producing hydrogen using nanoparticles, a catalyst, and a source of electrons, such as bacteria and their nutrient source in a biological system, are carried out in an aqueous medium. The nanoparticles may be doped with a plurality of isovalent and/or non-isovalent dopants.
    Type: Grant
    Filed: January 27, 2015
    Date of Patent: August 14, 2018
    Assignee: University of Rochester
    Inventors: Todd Krauss, Kara L. Bren
  • METHODS FOR PRODUCING HYDROGEN USING NANOPARTICLE-CATALYST MIXTURES
    Publication number: 20160024664
    Abstract: Methods for producing hydrogen using nanoparticles, a catalyst, and a source of electrons, such as bacteria and their nutrient source in a biological system, are carried out in an aqueous medium. The nanoparticles may be doped with a plurality of isovalent and/or non-isovalent dopants.
    Type: Application
    Filed: January 27, 2015
    Publication date: January 28, 2016
    Applicant: University of Rochester
    Inventors: Todd Krauss, Kara L. Bren
  • Method and system for purifying and quantitating proteins using heme fusion tags
    Patent number: 8815533
    Abstract: A method is provided for purifying a protein comprising the steps of providing a heme tag with an open coordination site and tagging the recombinant protein of interest with the heme tag. A resin framework is used, wherein a base that binds to heme is immobilized to the resin, and the open coordination site of the heme tag is capable of reversibly binding to the base immobilized to the resin. The tagged protein is reversibly bound to the resin, then eluted from the resin and quantified. The method enables the tagged protein to be tracked during protein expression or purification, and can be used to identify secretion of a protein to the periplasm or to tag proteins in the cytoplasm.
    Type: Grant
    Filed: January 28, 2011
    Date of Patent: August 26, 2014
    Assignee: University of Rochester
    Inventors: Kara L. Bren, Wesley B. Asher
  • METHOD AND SYSTEM FOR PURIFYING AND QUANTITATING PROTEINS USING HEME FUSION TAGS
    Publication number: 20130203101
    Abstract: A method is provided for purifying a protein comprising the steps of providing a heme tag with an open coordination site and tagging the recombinant protein of interest with the heme tag. A resin framework is used, wherein a base that binds to heme is immobilized to the resin, and the open coordination site of the heme tag is capable of reversibly binding to the base immobilized to the resin. The tagged protein is reversibly bound to the resin, then eluted from the resin and quantified. The method enables the tagged protein to be tracked during protein expression or purification, and can be used to identify secretion of a protein to the periplasm or to tag proteins in the cytoplasm.
    Type: Application
    Filed: January 28, 2011
    Publication date: August 8, 2013
    Applicant: UNIVERSITY OF ROCHESTER
    Inventors: Kara L. Bren, Wesley B. Asher