Abstract: Methods and systems for quantification of an abundance of one or more payloads (e.g. proteins) in a mixture (e.g. a complex mixture (e.g. in vivo)) using barcodes (e.g. peptide barcodes), binders (e.g. polypeptide binders), and binding agents (e.g. phage) are provided herein.

Abstract: Methods and systems for quantification of an abundance of one or more payloads (e.g. proteins) in a mixture (e.g. a complex mixture (e.g. in vivo)) using barcodes (e.g. peptide barcodes), binders (e.g. polypeptide binders), and binding agents (e.g. phage) are provided herein.

Abstract: Antibodies that specifically bind PD-1 or antigen binding fragments thereof, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of an inflammatory or immune disorder.

Abstract: Antibodies that specifically bind PD-1 or antigen binding fragments thereof, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of an inflammatory or immune disorder.

Abstract: Methods and systems for quantification of an abundance of one or more payloads (e.g. proteins) in a mixture (e.g. a complex mixture (e.g. in vivo)) using barcodes (e.g. peptide barcodes), binders (e.g. polypeptide binders), and binding agents (e.g. phage) are provided herein.

Abstract: Methods and systems for quantification of an abundance of one or more payloads (e.g. proteins) in a mixture (e.g. a complex mixture (e.g. in vivo)) using barcodes (e.g. peptide barcodes), binders (e.g. polypeptide binders), and binding agents (e.g. phage) are provided herein.

Abstract: Antibodies that specifically bind PD-1 or antigen binding fragments thereof, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of an inflammatory or immune disorder.

Abstract: Antibodies that specifically bind PD-1 or antigen binding fragments thereof, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of an inflammatory or immune disorder.

Abstract: The present invention relates to ST2L antagonists, polynucleotides encoding the antagonists or fragments thereof, and methods of making and using the foregoing.

Abstract: A near infrared spectrophotometric sensor assembly for non-invasive monitoring of blood oxygenation levels in a subject's body is provided. The assembly includes at least one light source, at least one light detector operable to detect light emitted by the light source, an electromagnetic interference shielding disposed around at least a portion of the light detector, wherein the electromagnetic interference shielding includes an electrically conductive substrate that is optically transparent, and one or both of a light blocking sheet disposed relative to at least one of the light detectors and an encapsulating material.

Abstract: According to an aspect of the present invention, a near infrared spectroscopy (NIRS) sensor assembly, system, and method for measuring a characteristic of a biological tissue is provided. The NIRS sensor assembly includes a light source, at least one light detector, and a subject contact layer. The light source is operable to emit light at one or more predetermined wavelengths. The light detector has an active area for detecting light emitted by the light source and passed through the biological tissue. The detector is operable to produce signals representative of the detected light. The subject contact layer is disposed to cover one or both of the light detector and the light source. The subject contact layer has at least one optically transmissive portion.

Abstract: The present invention relates to ST2L antagonists, polynucleotides encoding the antagonists or fragments thereof, and methods of making and using the foregoing.

Abstract: Antibodies that specifically bind PD-1 or antigen binding fragments thereof, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of an inflammatory or immune disorder.

Abstract: The present invention relates antibodies or antigen-binding fragments thereof specifically binding HLA-DR, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.

Abstract: The present invention relates to ST2L antagonists, polynucleotides encoding the antagonists or fragments thereof, and methods of making and using the foregoing.

Abstract: A NIRS sensor assembly includes a light source, a light detector, a first insulating layer, an EMI shielding layer, and a second insulating layer. The first insulating layer covers an exposed portion of the light detector. An optically transparent portion of the first insulating layer is aligned with an active area of the light detector. The EMI shielding layer covers the first insulating layer. An optically transparent portion of the EMI shielding layer is aligned with the active area of the light detector. The second insulating layer covers the EMI shielding layer and the first insulating layer. An optically transparent portion of the second insulating layer is aligned with the active area of the at least one light detector.

Abstract: The present invention relates to ST2L antagonists, polynucleotides encoding the antagonists or fragments thereof, and methods of making and using the foregoing.

Abstract: The present invention relates to ST2L antagonists, polynucleotides encoding the antagonists or fragments thereof, and methods of making and using the foregoing.

Abstract: According to an aspect of the present invention, a near infrared spectroscopy (NIRS) sensor assembly, system, and method for measuring a characteristic of a biological tissue is provided. The NIRS sensor assembly includes a light source, at least one light detector, and a subject contact layer. The light source is operable to emit light at one or more predetermined wavelengths. The light detector has an active area for detecting light emitted by the light source and passed through the biological tissue. The detector is operable to produce signals representative of the detected light. The subject contact layer is disposed to cover one or both of the light detector and the light source. The subject contact layer has at least one optically transmissive portion.

Abstract: An apparatus for electrically and mechanically coupling a connection portion of a sensor assembly with a connection portion of an interface cable is provided. The apparatus includes a frame having an EMI shielding material. The frame defines a first port operable to engage the connection portion of the sensor assembly and a second port operable to engage the connection portion of the interface cable. The frame includes attachment features operable to mechanically secure the connection portion of the sensor assembly and the connection portion of the interface cable relative to the frame. The frame is configured to provide a Faraday Cage around substantially all of the connection portion of the sensor assembly and the connection portion of the interface cable when the connection portions are in coupled configuration.