Patents by Inventor Karen J. Giroux

Karen J. Giroux has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Delivery vehicles for stem cells and uses thereof
    Patent number: 11027047
    Abstract: Provided herein according to some embodiments is a biocompatible scaffold comprising stem cells (e.g., a pliable scaffold) suitable for intracavity administration after surgical removal of a tumor, wherein the scaffold allows the stem cells to migrate away from the scaffold and towards a cancerous or damaged tissue, wherein the stem cells are loaded with a therapeutic agent and/or a reporter molecule. Methods of forming the scaffold, and methods of use thereof, are also provided.
    Type: Grant
    Filed: March 30, 2016
    Date of Patent: June 8, 2021
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Shawn D. Hingtgen, Julio Rodriguez Bago, Matthew G. Ewend, Karen J. Giroux, Raluca Dumitru
  • Active agents and their oligomers and polymers
    Patent number: 10092578
    Abstract: Conjugates comprising at least two active agents linked by a diglycolic acid or polyglycol diacid linker are disclosed. The invention also concerns oligomers and polymers of these conjugates and their use in therapeutic and industrial applications for localized, immediate or fast release delivery of an active agent, such as an anti-microbial, anti-infective, or antiseptic agent.
    Type: Grant
    Filed: July 9, 2015
    Date of Patent: October 9, 2018
    Assignee: Polymerix Corporation
    Inventors: Suseela Kanamathareddy, Karen J. Giroux
  • DELIVERY VEHICLES FOR STEM CELLS AND USES THEREOF
    Publication number: 20180064854
    Abstract: Provided herein according to some embodiments is a biocompatible scaffold comprising stem cells (e.g., a pliable scaffold) suitable for intracavity administration after surgical removal of a tumor, wherein the scaffold allows the stem cells to migrate away from the scaffold and towards a cancerous or damaged tissue, wherein the stem cells are loaded with a therapeutic agent and/or a reporter molecule. Methods of forming the scaffold, and methods of use thereof, are also provided.
    Type: Application
    Filed: March 30, 2016
    Publication date: March 8, 2018
    Inventors: Shawn D. Hingtgen, Julio Rodriguez Bago, Matthew G. Ewend, Karen J. Giroux, Raluca Dumitru
  • ACTIVE AGENTS AND THEIR OLIGOMERS AND POLYMERS
    Publication number: 20160058776
    Abstract: Conjugates comprising at least two active agents linked by a diglycolic acid or polyglycol diacid linker are disclosed. The invention also concerns oligomers and polymers of these conjugates and their use in therapeutic and industrial applications for localized, immediate or fast release delivery of an active agent, such as an anti-microbial, anti-infective, or antiseptic agent.
    Type: Application
    Filed: July 9, 2015
    Publication date: March 3, 2016
    Inventors: Suseela Kanamathareddy, Karen J. Giroux
  • Active agents and their oligomers and polymers
    Patent number: 9108070
    Abstract: Conjugates comprising at least two active agents linked by a diglycolic acid or polyglycol diacid linker are disclosed. The invention also concerns oligomers and polymers of these conjugates and their use in therapeutic and industrial applications for localized, immediate or fast release delivery of an active agent, such as an anti-microbial, anti-infective, or antiseptic agent.
    Type: Grant
    Filed: May 9, 2012
    Date of Patent: August 18, 2015
    Assignee: POLYMERIX CORPORATION
    Inventors: Suseela Kanamathareddy, Karen J. Giroux
  • ACTIVE AGENTS AND THEIR OLIGOMERS AND POLYMERS
    Publication number: 20130071458
    Abstract: Conjugates comprising at least two active agents linked by a diglycolic acid or polyglycol diacid linker are disclosed. The invention also concerns oligomers and polymers of these conjugates and their use in therapeutic and industrial applications for localized, immediate or fast release delivery of an active agent, such as an anti-microbial, anti-infective, or antiseptic agent.
    Type: Application
    Filed: May 9, 2012
    Publication date: March 21, 2013
    Inventors: Suseela Kanamathareddy, Karen J. Giroux
  • Medical devices employing novel polymers
    Patent number: 7985415
    Abstract: Medical devices with at least one surface comprising a polymer or polymers on the surface are provided. The polymer or polymers are capable of breaking down (e.g., including, but not limited to, hydrolyzing) in the physiologic milieu to form an active agent or agents under physiologic conditions, and can contain other active agents dispersed within or appended to the polymer matrix. Methods of delivering an active agent to an interior surface of a vein or artery are also provided.
    Type: Grant
    Filed: November 18, 2003
    Date of Patent: July 26, 2011
    Assignee: Rutgers, The State University of New Jersey
    Inventor: Karen J. Giroux
  • ACTIVE AGENTS AND THEIR OLIGOMERS AND POLYMERS
    Publication number: 20100310498
    Abstract: Conjugates comprising at least two active agents linked by a diglycolic acid or polyglycol diacid linker are disclosed. The invention also concerns oligomers and polymers of these conjugates and their use in therapeutic and industrial applications for localized, immediate or fast release delivery of an active agent, such as an anti-microbial, anti-infective, or antiseptic agent.
    Type: Application
    Filed: June 11, 2010
    Publication date: December 9, 2010
    Inventors: Suseela Kanamathareddy, Karen J. Giroux