Patents by Inventor Karen J. Watson-Straughan

Karen J. Watson-Straughan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Triamine derivative melanocortin receptor ligands and methods of using same
    Patent number: 6768024
    Abstract: The invention provides triamine derivative melanocortin receptor ligands of the formula: wherein R1 to R8 and n have the meanings provided herein. The invention further provides methods of using the ligands to alter or regulate the activity of a melanocortin receptor.
    Type: Grant
    Filed: August 4, 2000
    Date of Patent: July 27, 2004
    Assignee: Lion Bioscience AG
    Inventors: Karen J. Watson-Straughan, Timothy C. Gahman, Ming Qi, Christa Hamashin, James E. Macdonald, Michael J. Green, Kevin R. Holme, Michael C. Griffith
  • Melanocortin receptor-3 ligands to treat sexual dysfunction
    Patent number: 6534503
    Abstract: Methods for treating sexual dysfunction, such as erectile dysfunction or sexual arousal disorder, with a compound having the generic formula X1—X2-(D)Phe-Arg-(D)Trp-X3. A particularly useful compound is HP-228, which has the formula Ac-Nle-Gln-His-(D)Phe-Arg-(D)Trp-Gly-NH2. The invention also provides methods for selecting melanocortin receptor-3 ligands by determining whether a compound modulates the activity of MC-3 as an agonist or antagonist. These methods can be used to screen compound libraries for ligands to treat MC-3-associated conditions. Such conditions include sexual dysfunction, including erectile dysfunction and sexual arousal disorder.
    Type: Grant
    Filed: July 13, 2000
    Date of Patent: March 18, 2003
    Assignee: Lion Bioscience AG
    Inventors: Kevin C. Dines, Timothy C. Gahman, Beverly E. Girten, Douglas L. Hitchin, Kevin R. Holme, Hengyuan Lang, Sandra R. Slivka, Karen J. Watson-Straughan, Ronald R. Tuttle, Yazhong Pei