Patents by Inventor Karin Ann Stephenson

Karin Ann Stephenson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RESIDUALIZING LINKERS AND USES THEREOF
    Publication number: 20210060190
    Abstract: The present invention relates to conjugates including a residualizing linker, methods for their production, and uses thereof.
    Type: Application
    Filed: July 24, 2020
    Publication date: March 4, 2021
    Inventors: John Fitzmaurice Valliant, Eric Steven Burak, Neil Grant Cockbum, Alla Darwish, Joe Adamson Drewry, John Richard Forbes, Meiduo Hu, Ryan Wayne Simms, Karin Ann Stephenson, Tao Wu
  • Residualizing linkers and uses thereof
    Patent number: 10758636
    Abstract: The present invention relates to conjugates including a residualizing linker, methods for their production, and uses thereof.
    Type: Grant
    Filed: November 12, 2014
    Date of Patent: September 1, 2020
    Assignee: CENTRE FOR PROBE DEVELOPMENT AND COMMERCIALIZATION
    Inventors: John Fitzmaurice Valliant, Eric Steven Burak, Neil Grant Cockburn, Alla Darwish, Joel Adamson Drewry, John Richard Forbes, Meiduo Hu, Ryan Wayne Simms, Karin Ann Stephenson, Tao Wu
  • RESIDUALIZING LINKERS AND USES THEREOF
    Publication number: 20160279272
    Abstract: The present invention relates to conjugates including a residualizing linker, methods for their production, and uses thereof.
    Type: Application
    Filed: November 12, 2014
    Publication date: September 29, 2016
    Inventors: John Fitzmaurice VALLIANT, Eric Steven BURAK, Neil Grant COCKBURN, Alla DARWISH, Joel Adamson DREWRY, John Richard FORBES, Meiduo HU, Ryan Wayne SIMMS, Karin Ann STEPHENSON, Tao WU
  • Tc imaging agents and methods of use
    Patent number: 9125955
    Abstract: An embodiment of the invention comprises method of imaging a target site comprising administrating ligand of Formula I complexed to 99mTc wherein R1 and R2 are independently an alkyl or cycloalkyl; R3 is and alkyl; X is CO or SO2; Y is (CH2)n, C6H4, (OCH2CH2)n(NHCH2CH2)n and (OCH2CH2CH2)n, or a combination thereof; Z is linker group capable of conjugating to a vector; and n is an integer between 0 and 10.
    Type: Grant
    Filed: November 6, 2013
    Date of Patent: September 8, 2015
    Assignee: General Electric Company
    Inventors: Bruce Fletcher Johnson, Randall Lee Carter, Michael James Rishel, Mark Christopher Patrick Darey, Tao Wu, Yang Yang, John Fitzmaurice Valliant, Karin Ann Stephenson
  • Biotin stannane for HPLC-free radioiodination
    Patent number: 8927732
    Abstract: The present teachings provide methods that enable the preparation and purification of radioiodinated vectors without the need for HPLC purification, as well as novel precursors which include biotin-like substituents useful in such methods.
    Type: Grant
    Filed: March 30, 2012
    Date of Patent: January 6, 2015
    Assignee: General Electric Company
    Inventors: Randall Lee Carter, Bruce Fletcher Johnson, Anup Sood, Michael James Rishel, John Fitzmaurice Valliant, Karin Ann Stephenson, Tao Wu, Yang Yang
  • 99mTc IMAGING AGENTS AND METHODS OF USE
    Publication number: 20140065065
    Abstract: An embodiment of the invention comprises method of imaging a target site comprising administrating ligand of Formula I complexed to 99mTc wherein R1 and R2 are independently an alkyl or cycloalkyl; R3 is and alkyl; X is CO or SO2; Y is (CH2)n, C6H4, (OCH2CH2)n (NHCH2CH2)n and (OCH2CH2CH2)n, or a combination thereof; Z is linker group capable of conjugating to a vector; and n is an integer between 0 and 10.
    Type: Application
    Filed: November 6, 2013
    Publication date: March 6, 2014
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: Bruce Fletcher Johnson, Randall Lee Carter, Michael James Rishel, Mark Christopher Patrick Darey, Tao Wu, Yang Yang, John Fitzmaurice Valliant, Karin Ann Stephenson
  • BIOTIN STANNANE FOR HPLC-FREE RADIOIODINATION
    Publication number: 20130261311
    Abstract: The present teachings provide methods that enable the preparation and purification of radioiodinated vectors without the need for HPLC purification, as well as novel precursors which include biotin-like substituents useful in such methods.
    Type: Application
    Filed: March 30, 2012
    Publication date: October 3, 2013
    Applicants: Centre for Probe Development and Commercialization, General Electric Company
    Inventors: Randall Lee Carter, Bruce Fletcher Johnson, Anup Sood, Michael James Rishel, John Fitzmaurice Valliant, Karin Ann Stephenson, Tao Wu, Yang Yang
  • 99mTc IMAGING AGENTS AND METHODS OF USE
    Publication number: 20130195756
    Abstract: An embodiment of the invention comprises a ligand of Formula I wherein R1 and R2 are independently an alkyl or cycloalkyl; R3 is and alkyl; X is CO or SO2; Y is (CH2)n, C6H4, (OCH2CH2)n(NHCH2CH2)n and (OCH2CH2CH2)n, or a combination thereof; Z is linker group capable of conjugating to a vector; and n is an integer between 0 and 10. Also included are an imaging agent comprising a compound of Formula I complexed to 99mTc and their method of use to image a subject having a target site using single photon emission computed tomography (SPECT).
    Type: Application
    Filed: January 31, 2012
    Publication date: August 1, 2013
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: Bruce Fletcher Johnson, Randall Lee Carter, Michael James Rishel, Mark Christopher Patrick Darey, Tao Wu, Yang Yang, John Fitzmaurice Valliant, Karin Ann Stephenson