Patents by Inventor Karine Charton

Karine Charton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Red Cell Extracellular Vesicles (RCEVs) Containing Cargoes and Methods of Use and Production Thereof
    Publication number: 20230226218
    Abstract: The application relates to the use of loaded red blood cells (e.g. “RBCs”, “red cells” or “erythrocytes”) or red blood cell precursors to produce red cell extracellular vesicles (RCEVs) containing cargos, including cargos comprising biologically active ingredients. Notable red cell precursors include hematopoietic stem cells (HSCs), induced pluripotent stem cells (iPSCs), and reticulocytes. The cargo may comprise nucleic acids, proteins, small molecules, or components of a gene editing system, including CRISPR/Cas9. The RCEVs may be used to treat of diseases and disorders including autoimmune disorders, cancers, cardiovascular diseases, gastrointestinal diseases, genetic disorders, or inflammatory diseases. The RCEVs may also be used to carry antigens and or immune modulator, for use in eliciting immune or immune tolerance responses.
    Type: Application
    Filed: May 11, 2021
    Publication date: July 20, 2023
    Inventors: Karine CHARTON, Agnès CIBIEL, Anaïs BELLEDANT, Leidy Diana PIEDRAHITA ESPINOSA, Baptiste Alain MARTINON
  • CALPAIN-3 INHIBITORS FOR TREATING MUSCULAR DYSTROPHIES AND CARDIOMYOPATHIES
    Publication number: 20130171172
    Abstract: A composition comprising a calpain-3 inhibitor for treating muscular dystrophies and cardiomyopathies, in particular tibial muscular dystrophy (TMD).
    Type: Application
    Filed: June 30, 2011
    Publication date: July 4, 2013
    Applicants: Genethon, Universite D'Evry Val D'Essonne
    Inventors: Isabelle Richard, Karine Charton